Endocrinology

Menopause

Latest AI and machine learning research in menopause for healthcare professionals.

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When neural implant meets multimodal LLM: A dual-loop system for neuromodulation and naturalistic neuralbehavioral research

We propose a novel dual-loop system that synergistically combines responsive neurostimulation (RNS) implants with artificial intelligence-driven wearable devices for treating post-traumatic stress disorder (PTSD) and enabling naturalistic brain research. In PTSD Therapy Mode, an implanted closed-loop neural device monitors amygdala activity and provides on-demand stimulation upon detecting patho...

Assessing the effects of immune checkpoint inhibitors on bone utilizing machine learning-assisted opportunistic quantitative computed tomography.

Immune checkpoint inhibitors (ICIs) are widely used in cancer treatment, yet their impact on bone health remains unclear. This study aimed to perform a retrospective cohort study utilizing routine CT scans from patients with melanoma to perform opportunistic QCT analysis to investigate the effects of ICI treatment on skeletal health, including volumetric BMD (vBMD) measurements and osteoarthritis ...

Mar 15 2025 39849845
FLASHμ: Fast Localizing And Sizing of Holographic Microparticles

Reconstructing the 3D location and size of microparticles from diffraction images - holograms - is a computationally expensive inverse problem that ...

Smoothing ADMM for Non-convex and Non-smooth Hierarchical Federated Learning

This paper presents a hierarchical federated learning (FL) framework that extends the alternating direction method of multipliers (ADMM) with smooth...

A Deep Learning Model for Three-Dimensional Determination of Whole Thoracic Vertebral Bone Mineral Density from Noncontrast Chest CT: The Multi-Ethnic Study of Atherosclerosis.

Background Recent studies have investigated how deep learning (DL) algorithms applied to CT using two-dimensional (2D) segmentation (sagittal or axial...

Mar 1 2025 40067103
Night-Voyager: Consistent and Efficient Nocturnal Vision-Aided State Estimation in Object Maps

Accurate and robust state estimation at nighttime is essential for autonomous robotic navigation to achieve nocturnal or round-the-clock tasks. An i...

Asymptotics of Non-Convex Generalized Linear Models in High-Dimensions: A proof of the replica formula

The analytic characterization of the high-dimensional behavior of optimization for Generalized Linear Models (GLMs) with Gaussian data has been a ce...

Multimodal Cognitive Reframing Therapy via Multi-hop Psychotherapeutic Reasoning

Previous research has revealed the potential of large language models (LLMs) to support cognitive reframing therapy; however, their focus was primar...

An Optimized YOLOv5 Based Approach For Real-time Vehicle Detection At Road Intersections Using Fisheye Cameras

Real time vehicle detection is a challenging task for urban traffic surveillance. Increase in urbanization leads to increase in accidents and traffi...

Are the Majority of Public Computational Notebooks Pathologically Non-Executable?

Computational notebooks are the de facto platforms for exploratory data science, offering an interactive programming environment where users can cre...

A Mixed-Methods Evaluation of LLM-Based Chatbots for Menopause

The integration of Large Language Models (LLMs) into healthcare settings has gained significant attention, particularly for question-answering tasks...

Subjective and Objective Quality Assessment of Non-Uniformly Distorted Omnidirectional Images

Omnidirectional image quality assessment (OIQA) has been one of the hot topics in IQA with the continuous development of VR techniques, and achieved...

Personality Modeling for Persuasion of Misinformation using AI Agent

The proliferation of misinformation on social media platforms has highlighted the need to understand how individual personality traits influence sus...

Flash Window Attention: speedup the attention computation for Swin Transformer

To address the high resolution of image pixels, the Swin Transformer introduces window attention. This mechanism divides an image into non-overlappi...

Guiding Treatment Strategies: The Role of Adjuvant Anti-Her2 Neu Therapy and Skin/Nipple Involvement in Local Recurrence-Free Survival in Breast Cancer Patients

This study explores how causal inference models, specifically the Linear Non-Gaussian Acyclic Model (LiNGAM), can extract causal relationships betwe...

ODFormer: a Virtual Organoid for Predicting Personalized Therapeutic Responses in Pancreatic Cancer

Pancreatic cancer (PC) patient-derived organoids (PDOs) faithfully recapitulate therapeutic responses but face clinical translation barriers, includin...

Mechanistically Informed Machine Learning Links Non-Canonical TCA Cycle Activity to Warburg Metabolism and Hallmarks of Malignancy

Cancer cells undergo extensive metabolic rewiring to support growth, survival, and phenotypic plasticity. A non-canonical variant of the tricarboxylic...

E2-Regulated Transcriptome Complexity Revealed by Long-Read Direct RNA Sequencing: From Isoform Discovery to Truncated Proteins

Estrogen receptor alpha (ERα)-positive (ER+) breast cancers are driven by 17β-estradiol (E2) binding to ERα, which transcriptionally regulates downstr...

NucEL: Single-Nucleotide ELECTRA-Style Genomic Pre-training for Efficient and Interpretable Representations

Pre-training large language models on genomic sequences has become a powerful approach for learning biologically meaningful representations. While mas...

Design of peptides with non-canonical amino acids using flow matching

The canonical vocabulary of twenty amino acids limits the chemical space available to proteins and peptides. Expanding this vocabulary to hundreds of ...

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