Menopause

Computer-Aided Osteoporosis Diagnosis Using Transfer Learning with Enhanced Features from Stacked Deep Learning Modules

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee osteoporosis through manual radiology evaluation and traditional machine learning using hand-crafted features, these methods often struggle with performance and...

The Helicobacter pylori AI-Clinician: Harnessing Artificial Intelligence to Personalize H. pylori Treatment Recommendations

Helicobacter pylori (H. pylori) is the most common carcinogenic pathogen worldwide. Infecting roughly 1 in 2 individuals globally, it is the leading cause of peptic ulcer disease, chronic gastritis, and gastric cancer. To investigate whether personalized treatments would be optimal for patients suffering from infection, we developed the H. pylori AI-clinician recommendation system. This system w...

Osteoporosis Prediction from Hand X-ray Images Using Segmentation-for-Classification and Self-Supervised Learning

Osteoporosis is a widespread and chronic metabolic bone disease that often remains undiagnosed and untreated due to limited access to bone mineral d...

BinSparX: Sparsified Binary Neural Networks for Reduced Hardware Non-Idealities in Xbar Arrays

Compute-in-memory (CiM)-based binary neural network (CiM-BNN) accelerators marry the benefits of CiM and ultra-low precision quantization, making th...

Scalable Image Tokenization with Index Backpropagation Quantization

Existing vector quantization (VQ) methods struggle with scalability, largely attributed to the instability of the codebook that undergoes partial up...

Concept Replacer: Replacing Sensitive Concepts in Diffusion Models via Precision Localization

As large-scale diffusion models continue to advance, they excel at producing high-quality images but often generate unwanted content, such as sexual...

Evaluation of machine learning algorithms and computational structural validation of CYP2D6 in predicting the therapeutic response to tamoxifen in breast cancer.

OBJECTIVE: CYP2D6 plays a critical role in metabolizing tamoxifen into its active metabolite, endoxifen, which is crucial for its therapeutic effect i...

FlexiBit: Fully Flexible Precision Bit-parallel Accelerator Architecture for Arbitrary Mixed Precision AI

Recent research has shown that large language models (LLMs) can utilize low-precision floating point (FP) quantization to deliver high efficiency wh...

SpecPCM: A Low-power PCM-based In-Memory Computing Accelerator for Full-stack Mass Spectrometry Analysis

Mass spectrometry (MS) is essential for proteomics and metabolomics but faces impending challenges in efficiently processing the vast volumes of dat...

Redundancy Is All You Need

The seminal work of Bencz\'ur and Karger demonstrated cut sparsifiers of near-linear size, with several applications throughout theoretical computer...

Modeling the Popularity of Events on Web by Sparsity and Mutual-Excitation Guided Graph Neural Network

The content of a webpage described or posted an event in the cyberspace inevitably reflects viewpoints, values and trends of the physical society. M...

Efficient and Reliable Vector Similarity Search Using Asymmetric Encoding with NAND-Flash for Many-Class Few-Shot Learning

While memory-augmented neural networks (MANNs) offer an effective solution for few-shot learning (FSL) by integrating deep neural networks with exte...

Fracture risk prediction in postmenopausal women with traditional and machine learning models in a nationwide, prospective cohort study in Switzerland with validation in the UK Biobank.

Fracture prediction is essential in managing patients with osteoporosis and is an integral component of many fracture prevention guidelines. We aimed ...

Vertebral compression fractures at abdominal CT: underdiagnosis, undertreatment, and evaluation of an AI algorithm.

Vertebral compression fractures (VCFs) are common and indicate a high future risk of additional osteoporotic fractures. However, many VCFs are unrepor...

Can we screen opportunistically for low bone mineral density using CT scans of the shoulder and artificial intelligence?

OBJECTIVE: To evaluate whether the CT attenuation of bones seen on shoulder CT scans could be used to predict low bone mineral density (BMD) (osteopen...

Are gene-by-environment interactions leveraged in multi-modality neural networks for breast cancer prediction?

Polygenic risk scores (PRSs) can significantly enhance breast cancer risk prediction when combined with clinical risk factor data. While many studie...

Unravelling tumour cell diversity and prognostic signatures in cutaneous melanoma through machine learning analysis.

Melanoma, a highly malignant tumour, presents significant challenges due to its cellular heterogeneity, yet research on this aspect in cutaneous melan...

On Discrete Prompt Optimization for Diffusion Models

This paper introduces the first gradient-based framework for prompt optimization in text-to-image diffusion models. We formulate prompt engineering ...

Revolutionizing Mental Health Support: An Innovative Affective Mobile Framework for Dynamic, Proactive, and Context-Adaptive Conversational Agents

As we build towards developing interactive systems that can recognize human emotional states and respond to individual needs more intuitively and em...

Development and Validation of Fully Automatic Deep Learning-Based Algorithms for Immunohistochemistry Reporting of Invasive Breast Ductal Carcinoma

Immunohistochemistry (IHC) analysis is a well-accepted and widely used method for molecular subtyping, a procedure for prognosis and targeted therap...