Menopause

HLAncPred: a method for predicting promiscuous non-classical HLA binding sites.

Human leukocyte antigens (HLA) regulate various innate and adaptive immune responses and play a crucial immunomodulatory role. Recent studies revealed that non-classical HLA-(HLA-E & HLA-G) based immunotherapies have many advantages over traditional HLA-based immunotherapy, particularly against cancer and COVID-19 infection. In the last two decades, several methods have been developed to predict t...

Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan.

Graves disease (GD) and type 2 diabetes mellitus (T2DM) both impair liver function; we therefore explored the possibility of a relationship among diabetic control, thyroid function, and liver function. This retrospective, cross-sectional study compared serum liver function biomarkers of primary GD patients in a single center between 2016 and 2020, derived from clinical databases, and clarified the...

Development of Needle Guide Unit Considering Buckling Bone-Perforation Control Strategy Based on Computed Tomography-Guided Needle Insertion Robot.

A computed tomography (CT)-guided robotic assistance system is useful for needle insertion into metastatic carcinoma of vertebrae, which has limited p...

ARMStick - An Intuitive Therapist Interface for Upper-Limb Rehabilitation Robots.

Currently, therapists struggle with interaction of rehabilitation robots due to non-intuitive interfaces. Therefore their acceptance of these robots a...

Optical bone densitometry robust to variation of soft tissue using machine learning techniques: validation by Monte Carlo simulation.

SIGNIFICANCE: To achieve early detection of osteoporosis, a simple bone densitometry method using optics was proposed. However, individual differences...

Ultrasonographic morphological characteristics determined using a deep learning-based computer-aided diagnostic system of breast cancer.

To investigate the correlations between ultrasonographic morphological characteristics quantitatively assessed using a deep learning-based computer-ai...

Chronic Beneficial Effect of Makeup Therapy on Cognitive Function of Dementia and Facial Appearance Analyzed by Artificial Intelligence Software.

BACKGROUND: Makeup greatly impacts normal social lives but can also be a non-pharmacological form of therapy for dementia.

Comparison of concordance between chuna manual therapy diagnosis methods (palpation, X-ray, artificial intelligence program) in lumbar spine: An exploratory, cross-sectional, prospective observational study protocol.

INTRODUCTION: Chuna manual therapy (CMT) is a type of manual medicine practiced by Korean medical doctors in South Korea. Spinal diagnosis in CMT uses...

Construction of a 5-feature gene model by support vector machine for classifying osteoporosis samples.

Osteoporosis is a progressive bone disease in the elderly and lacks an effective classification method of patients. This study constructed a gene sign...

Augmenting Osteoporosis Imaging with Machine Learning.

PURPOSE OF REVIEW: In this paper, we discuss how recent advancements in image processing and machine learning (ML) are shaping a new and exciting era ...

Impact feature recognition method for non-stationary signals based on variational modal decomposition noise reduction and support vector machine optimized by whale optimization algorithm.

It is difficult to effectively distinguish the key information of non-stationary dynamic signals in many engineering applications, such as fault detec...

Special issue: Informatics & data-driven medicine.

The current state of the development of Medicine today is changing dramatically. Previously, data of the patient's health were collected only during a...

Using Deep Learning for Individual-Level Predictions of Adherence with Growth Hormone Therapy.

The problem of consistent therapy adherence is a current challenge for health informatics, and its solution can increase the success rate of treatment...

Opportunistic Screening at Abdominal CT: Use of Automated Body Composition Biomarkers for Added Cardiometabolic Value.

Abdominal CT is a frequently performed imaging examination for a wide variety of clinical indications. In addition to the immediate reason for scannin...

[Determination of four bisphenol environmental hormone residues in infant serum by liquid chromatography-tandem mass spectrometry].

Bisphenols are important industrial raw materials that are widely used to produce plastic bottles (feeding bottles), infant cups, and food and beverag...

Dermoscopic Features of Giant Molluscum Contagiosum in a Patient with Acquired Immunodeficiency Syndrome.

Giant molluscum contagiosum (MC) is a peculiar variant of the disease with the presence of multiple or single lesions larger than 5 mm. In contrast to...

Fennel fortified diet: New perspective with regard to fertility and sex hormones.

The objective of this study was to evaluate the effect of Foeniculum vulgare (FV) on fertility of mice and on serum sex hormone values of rats and rab...

Convolutional neural network-based annotation of bacterial type IV secretion system effectors with enhanced accuracy and reduced false discovery.

The type IV bacterial secretion system (SS) is reported to be one of the most ubiquitous SSs in nature and can induce serious conditions by secreting ...

[A comparative study on treatment of lumbar degenerative disease with osteoporosis by manual and robot-assisted cortical bone trajectory screws fixation].

OBJECTIVE: To compare the safety and accuracy of manual and robot-assisted cortical bone trajectory (CBT) screws fixation in the treatment of lumbar d...

Deformable US/CT Image Registration with a Convolutional Neural Network for Cardiac Arrhythmia Therapy.

Image registration represents one of the fundamental techniques in medical imaging and image-guided interventions. In this paper, we present a Convolu...