Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement.

BACKGROUND: The impact of pulmonary hypertension (PH) on outcomes after surgical tricuspid valve replacement (TVR) and repair (TVr) is unclear. We sought to characterize PH in patients undergoing TVR/TVr, based on invasive hemodynamics and evaluate the effect of PH on mortality.

Dec 16 2020 34027352

Next-Generation Bioelectric Medicine: Harnessing the Therapeutic Potential of Neural Implants.

Bioelectric medicine leverages natural signaling pathways in the nervous system to counteract organ dysfunction. This novel approach has potential to address conditions with unmet needs, including heart failure, hypertension, inflammation, arthritis, asthma, Alzheimer's disease, and diabetes. Neural therapies, which target the brain, spinal cord, or peripheral nerves, are already being applied to ...

Dec 16 2020 34476364
A novel method to rapidly calculate the urea clearance index and urea reduction rate based on parameters obtained during hemodialysis.

BACKGROUND: The efficacy of hemodialysis (HD) is closely associated with patient survival time and quality of life. The classical method (CLM) to calc...

Dec 14 2020 34013179
Development of a quantitative systems pharmacology model of chronic kidney disease: metabolic bone disorder.

Chronic kidney disease mineral bone disorder (CKD-MBD) is a virtually universal complication of kidney diseases, starting early in the course of disea...

Dec 14 2020 33308018
The Emerging Hazard of AI-Related Health Care Discrimination.

Artificial intelligence holds great promise for improved health-care outcomes. But it also poses substantial new hazards, including algorithmic discri...

Dec 14 2020 33315263
In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining.

To understand the physiology and pathology of disease, capturing the heterogeneity of cell types within their tissue environment is fundamental. In su...

Dec 13 2020 33252180
Early initiation of PD therapy in elderly patients is associated with increased risk of death.

BACKGROUND: The effect of early initiation of dialysis on outcomes of patients with end-stage renal disease (ESRD) remains controversial. We conducted...

Dec 12 2020 34084460
Impact of Supplementation with Omega-3 in the Prevention of Contrast-Induced Nephropathy Following Elective Percutaneous Coronary Intervention in Patients with Chronic Kidney Disease: A Randomized Placebo-Controlled Trial.

BACKGROUND: Anti-oxidants were investigated in several studies as a preventive strategy for prevention of contrast-induced nephropathy (CIN). Omega-3 ...

Dec 11 2020 33815717
Value of Doppler ultrasound in early detection of diabetic kidney disease: A systematic review and meta-analysis.

The diagnosis of diabetic kidney disease can be delayed by limitations of primary biomarkers, which are microalbuminuria and estimated glomerular filt...

Dec 8 2020 34567226
Image-Based Machine Learning Algorithms for Disease Characterization in the Human Type 1 Diabetes Pancreas.

Emerging data suggest that type 1 diabetes affects not only the β-cell-containing islets of Langerhans, but also the surrounding exocrine compartment....

Dec 8 2020 33307036
Retroperitoneal robot-assisted laparoscopic partial nephrectomy for posterior located renal tumours: Technique and early term outcomes.

BACKGROUND: Traditionally, the trans-peritoneal approach is preferred for robot-assisted partial nephrectomy (RPN). However, retroperitoneal RPN (RP-R...

Dec 8 2020 33237611
XGBoost Model for Chronic Kidney Disease Diagnosis.

Chronic Kidney Disease (CKD) is a menace that is affecting 10 percent of the world population and 15 percent of the South African population. The earl...

Dec 8 2020 30998478
Estimating the health-related quality of life of kidney stone patients: initial results from the Wisconsin Stone Quality of Life Machine-Learning Algorithm (WISQOL-MLA).

OBJECTIVE: To build the Wisconsin Stone Quality of Life Machine-Learning Algorithm (WISQOL-MLA) to predict urolithiasis patients' health-related quali...

Dec 7 2020 33205549
The Use of Synthetic Electronic Health Record Data and Deep Learning to Improve Timing of High-Risk Heart Failure Surgical Intervention by Predicting Proximity to Catastrophic Decompensation.

Although many clinical metrics are associated with proximity to decompensation in heart failure (HF), none are individually accurate enough to risk-s...

Dec 7 2020 34713050
Urine concentrating defect as presenting sign of progressive renal failure in Bardet-Biedl syndrome patients.

BACKGROUND: Urine concentrating defect is a common dysfunction in ciliopathies, even though its underlying mechanism and its prognostic meaning are la...

Dec 6 2020 34084454
Multi-institutional Retrospective Validation and Comparison of the Simplified PADUA REnal Nephrometry System for the Prediction of Surgical Success of Robot-assisted Partial Nephrectomy.

BACKGROUND: The use of a nephron-sparing surgery for the treatment of localized renal masses is being pushed to more challenging cases. However, this ...

Dec 4 2020 33272907
A scientometric study of the top 100 most-cited publications based on Web-of-Science regarding robotic versus laparoscopic surgery.

Minimally invasive surgery includes traditional laparoscopic and robot-assisted surgery. Although many studies related to robotic surgery and laparosc...

Dec 4 2020 33288372
Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum.

The endoplasmic reticulum (ER) is a complex subcellular organelle composed of diverse structures such as tubules, sheets and tubular matrices. Flavivi...

Dec 1 2020 33262363
Development and Validation of a Machine Learning Model to Explore Tyrosine Kinase Inhibitor Response in Patients With Stage IV EGFR Variant-Positive Non-Small Cell Lung Cancer.

IMPORTANCE: An end-to-end efficacy evaluation approach for identifying progression risk after epidermal growth factor receptor (EGFR)-tyrosine kinase ...

Dec 1 2020 33331920
Retinal Capillary Nonperfusion on OCT-Angiography and Its Relationship to Kidney Function in Patients with Diabetes.

BACKGROUND: Diabetic retinopathy and kidney disease share underlying mechanisms of microvascular damage and are often comorbid in people with diabetes...

Nov 30 2020 33763237
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