Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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RAGCBPNet: An Efficient Feature Fusion Framework for Wearable Cuffless Blood Pressure Monitoring and Long-term Validation in Real-world Settings

Wearable and cuffless blood pressure (BP) monitoring hold great promise for preventive hypertension management, yet few studies have been validated under real-world and long-term conditions. In this study, we propose RACGBPNet, an efficient yet effective feature fusion framework for cuffless BP estimation and hypertension detection. The model leverages a two-stage fusion strategy: first, handcraft...

Enhancing Anterior Quadratus Lumborum Block Accuracy with Artificial Intelligence: A Segmentation Approach Evaluated by Dice Score Metrics

Anterior quadratus lumborum (QL) block is a regional anesthesia technique shown to provide both somatic and visceral pain relief by targeting lower thoracic nerves and the thoracic sympathetic trunk. Despite its clinical benefits, success depends on accurate sonoanatomic identification, which can be challenging due to individual anatomical variations. In this study, we developed an artificial inte...

Ambient Only vs. Longitudinal Data-Enhanced AI Documentation: A Pilot Study Quantifying the Value of Historical Clinical Context in Primary Care

Ambient artificial intelligence (AI) clinical documentation tools have gained rapid adoption in healthcare to address physician burnout from documenta...

Development and validation of Retrieval Augmented Generation (RAG) and GraphRAG for complex clinical cases

Chronic Kidney Disease (CKD) is a progressive condition requiring evidence-based management, but adherence to complex guidelines remains challenging. ...

Characterize Disease Progression Subphenotypes in Real World Populations with Overweight and Obesity using a Graph-based Neural Network Framework

Obesity is a chronic, heterogeneous condition, with risks, trajectories, and treatment responses that vary widely among individuals. However, research...

Visionary AI: Decoding Systemic Vascular Health and Hypertensive Disorders in Pregnancy Through Retinal Imaging and Artificial Intelligence

Pregnancy orchestrates a rare physiological transformation across vascular, immune, and metabolic systems. When this dynamic balance is disrupted – as...

Synthesizing Contrast-Enhanced T1 MR Image Using Multiparametric Sequences and Attention to Brain Tumor

The administration of gadolinium-based contrast agents (GBCAs) for acquiring contrast-enhanced T1-weighted magnetic resonance imaging (T1C MRI) is ass...

Precision Immunosuppression and Long-Term Kidney Transplant Outcomes: A Dual Survival Modeling Framework

Optimizing immunosuppressive therapy remains central to improving long-term outcomes after kidney transplantation. Both induction and maintenance ther...

Performance of reasoning large language models on nephrology multiple-choice questions

Performance of large language models in medicine is improving, yet it remains unclear how the advantage of reasoning models depends on task characteri...

Machine Learning Prediction of Blood Pressure Control in Patients With Hypertension and Heart Failure Using Longitudinal Clinical Data

To develop and validate machine learning models for predicting Blood Pressure (BP) control status using demographic characteristics and longitudinal B...

Opportunistically Detecting Signs of Hypertension on a Consumer Smartwatch

Hypertension is a silent killer, with over half of affected adults unaware of their condition1,2. This lack of awareness is a major concern, as early ...

Conversational Artificial Intelligence-Based Integration of Clinical and Genomic Data Identifies MAPK Alterations in Colorectal Cancer

Colorectal cancer (CRC) exhibits marked heterogeneity across age, ancestry, and treatment context, underscored by the rising incidence of early-onset ...

Rx-LLM: a benchmarking suite to evaluate safe large language model performance for medication-related tasks

For large language models (LLMs) to reach their potential as information technology tools that make medication use safer, clinically relevant benchmar...

Understanding Uncertainty in Large Language Model Predictions of Early Death in Critically Ill Patients: A Conformal Prediction Approach

Early prediction of in-hospital death remains a significant challenge due to the limited availability of structured data during initial admission. Uns...

A proteogenomic atlas of idiopathic pulmonary arterial hypertension reveals sex-dimorphic mechanisms and potential novel therapeutic targets

Current circulating biomarkers for idiopathic pulmonary arterial hypertension (IPAH) lack specificity for preclinical detection and fail to capture th...

Clinical characteristics, prognosis, and predictive modeling in class IV ± V lupus nephritis.

OBJECTIVE: The objective of this study is to compare the clinical features and survival outcomes of class IV ± V lupus nephritis (LN) patients, identi...

Jan 1 2025 40443677
Donor-specific digital twin for living donor liver transplant recovery.

The remarkable capacity of the liver to regenerate its lost mass after resection makes living donor liver transplantation a successful treatment optio...

Jan 1 2025 40486178
Emerging biomaterials and bio-nano interfaces in pulmonary hypertension therapy: transformative strategies for personalized treatment.

Pulmonary hypertension (PH) is still an aggressive and progressive illness with vascular remodeling and right heart failure despite the therapeutic ad...

Jan 1 2025 40416311
Machine learning with decision curve analysis evaluates nutritional metabolic biomarkers for cardiovascular-kidney-metabolic risk: an NHANES analysis.

BACKGROUND: The American Heart Association recently introduced the concept of Cardiovascular-Kidney-Metabolic Syndrome (CKM), emphasizing the interpla...

Jan 1 2025 40406158
Predicting in-hospital mortality in patients with alcoholic cirrhosis complicated by severe acute kidney injury: development and validation of an explainable machine learning model.

BACKGROUND: At present, there are no specialized models for predicting mortality risk in patients with alcoholic cirrhosis complicated by severe acute...

Jan 1 2025 40406405
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