Nephrology

External Validation of a CT-Based Radiogenomics Model for the Detection of EGFR Mutation in NSCLC and the Impact of Prevalence in Model Building by Using Synthetic Minority Over Sampling (SMOTE): Lessons Learned.

RATIONALE AND OBJECTIVES: Radiogenomics holds promise in identifying molecular alterations in nonsma...

Exosomes derived from human umbilical cord mesenchymal stem cells attenuate senescence of peritoneal mesothelial cells by inhibiting oxidative stress.

OBJECTIVE: Aging is a natural process that affects cellular function. In peritoneal dialysis (PD), c...

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib.

Fruquintinib (FRUZAQLA) is a highly selective tyrosine kinase inhibitor of all three vascular endoth...

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin-Independent Regulation of Fpn mRNA.

The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) ...

Push Forward Clinical Management of Hematological Toxicity due to Lenalidomide Overexposure: Model-Informed Precision Dosing for Chinese Population With Renal Insufficiency.

Dose-dependent hematological toxicity of lenalidomide has been reported previously, and thus, there ...

Semi-quantitative analysis of Right Ventricular Myocardial First-pass Perfusion Using Cardiac Magnetic Resonance Imaging in Systemic Sclerosis and Pulmonary Arterial Hypertension.

BACKGROUND: Right ventricular (RV) myocardial perfusion has been touted as a primary mechanism to un...

Inadequate imipenem dosing in patients with decreased kidney function: A clinical pharmacokinetic study.

OBJECTIVES: A number of population pharmacokinetic (popPK) models of imipenem in critically ill pati...

Enhancing clinical decision-making in closed pelvic fractures with machine learning models.

Closed pelvic fractures can lead to severe complications, including hemodynamic instability (HI) and...

55 MHz constant field dielectric warming of kidneys and ovaries cryopreserved by vitrification.

Organs cryopreserved by vitrification benefit from fast warming to avoid growth and recrystallizatio...

Comparison of Machine Learning Algorithms and Bayesian Estimation in Predicting Tacrolimus Concentration in Tunisian Kidney Transplant Patients During the Early Post-Transplant Period.

BACKGROUND AND OBJECTIVE: Model-informed precision dosing (MIPD), based on a Bayesian approach and m...

AI-driven glomerular morphology quantification: a novel pipeline for assessing basement membrane thickness and podocyte foot process effacement in kidney diseases.

BACKGROUND AND OBJECTIVE: Measuring the thickness of the glomerular basement membrane (GBM) and asse...

Artificial Intelligence: The New Transplant Selection Committee Member.

Enhancing Organ Allocation Efficiency: A Pilot Study Evaluating Artificial Intelligence-Assisted Assessment of Donor Kidney Pathology.

PURPOSE: The purpose of this study is to evaluate the effectiveness of an artificial intelligence (A...

Active Organic Salts Enabling Non-Intrusive Electrolyte Presodiation Strategy.

Na-ion batteries show great promise, but their practical utilization is hindered by irreversible Na-...

Machine learning-derived multivariate renal function trajectories in acute kidney injury in critically ill patients: a multicentre retrospective study.

BACKGROUND: Acute kidney injury (AKI) exhibits considerable heterogeneity. The objective of the curr...

Prediction of perimetric progression in ocular hypertension and open angle glaucoma based on corneal biomechanics.

PurposeTo identify parameters that are significant risk predictors of visual field (VF) progression ...

Latent space autoencoder generative adversarial model for retinal image synthesis and vessel segmentation.

Diabetes is a widespread condition that can lead to serious vision problems over time. Timely identi...

Machine learning models for acute kidney injury prediction and management: a scoping review of externally validated studies.

Despite advancements in medical care, acute kidney injury (AKI) remains a major contributor to adver...

GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma.

Glioblastoma (GBM) is a fatal brain cancer known for its rapid and aggressive growth, with some stud...

Agreement Between AI and Nephrologists in Addressing Common Patient Questions About Diabetic Nephropathy: Cross-Sectional Study.

This research letter presents a cross-sectional analysis comparing the agreement between artificial ...

Recruiting Teacher IF Modality for Nephropathy Diagnosis: A Customized Distillation Method With Attention-Based Diffusion Network.

The joint use of multiple modalities for medical image processing has been widely studied in recent ...