Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Insights into the interplay between stroke and depression through lipid metabolism-related diagnostic genes.

Stroke, a result of acute cerebrovascular disease that causes cerebral dysfunction, often coexists with depression or even major depressive disorder (MDD). Despite the recognized significance of lipid metabolism disorders in both stroke and depression, their interwoven role in the pathogenesis of these conditions remains largely uncharted. This study sourced transcriptomic data linked to stroke an...

Jan 18 2026 41547864

Identifying the state of cerebrovascular autoregulation using the pressure reactivity index versus the mean flow index: Why metric matters.

Cerebral autoregulation maintains stable cerebral blood flow despite fluctuations in cerebral perfusion pressure (CPP), through mechanisms that alter vascular diameter and resistance. Two commonly used indices, pressure reactivity index and mean flow index, reflect different aspects of this regulation, namely changes in cerebral blood volume and blood flow velocity. However, their interchangeabili...

Jan 18 2026 41549342
Using Expert-Cited Features to Detect Leg Dystonia in Cerebral Palsy.

OBJECTIVES: Leg dystonia in cerebral palsy (CP) is debilitating but remains underdiagnosed. Routine clinical evaluation has only 12% accuracy for leg ...

Jan 18 2026 41549584
Analytical Approaches for the Determination of Lidocaine and Its Metabolites: A Comprehensive Insight.

Lidocaine (LID), an amide-type local anesthetic and antiarrhythmic agent, remains one of the most extensively used drugs in medical, dental, and surgi...

Jan 18 2026 41549994
Transfer learning from 2D natural images to 4D fMRI brain images via geometric mapping.

Functional magnetic resonance imaging (fMRI) allows real-time observation of brain activity through blood oxygen level-dependent (BOLD) signals and is...

Jan 17 2026 41576824
Identifying and predicting gait stability metrics in people with stroke in uneven-surface walking using machine learning.

People with stroke (PwS) face increased fall risk on uneven surfaces; however, gait stability under such conditions remains unexplored. This study use...

Jan 17 2026 41547919
Biomarker discovery in Lennox-Gastaut syndrome: Advances and challenges in electrophysiological, genetic, neuroimaging, and neuroinflammatory approaches.

In Lennox-Gastaut Syndrome (LGS), a severe developmental and epileptic encephalopathy, the absence of validated biomarkers limits our ability to detec...

Jan 17 2026 41548392
U2AD: Uncertainty-based unsupervised anomaly detection framework for detecting T2 hyperintensity in MRI spinal cord.

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy (DCM). However, current cl...

Jan 17 2026 41558246
Rebuilding the pelvis: advances in robotic-assisted management of complex pelvic fractures.

Complex pelvic fractures are infamously challenging to fix surgically because of their fine anatomy and proximity to vital neurovascular structures. T...

Jan 16 2026 41543252
EEG-to-gait decoding via phase-aware representation learning.

Accurate decoding of lower-limb motion from EEG signals is essential for advancing brain-computer interface (BCI) applications in movement intent reco...

Jan 16 2026 41570674
Comparative analysis of machine learning algorithms for predicting stereotactic coordinates of the centromedian nucleus.

OBJECTIVE: Deep brain stimulation (DBS) of the centromedian nucleus (CM) of the thalamus is a promising treatment for drug-resistant epilepsy, Tourett...

Jan 16 2026 41569646
Multisequence MRI Enables High-Fidelity FDG-PET Synthesis for Epilepsy Using GANs.

BACKGROUND: FDG-PET aids presurgical epilepsy evaluation but is limited by access and radiation exposure. PURPOSE: To evaluate synthetic FDG-PET gener...

Jan 16 2026 41542825
Japan Brain Bank Net (JBBN).

Autopsies have long been performed to determine the cause of death in the medical field. In fact, autopsies have significantly contributed to our unde...

Jan 16 2026 41542899
Multi-omics Mendelian randomization and machine learning identify candidate therapeutic targets for Alzheimer's and Parkinson's diseases.

Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are major public health challenges lacking effecti...

Jan 16 2026 41543776
Opportunities and Challenges in Precision Neurotherapeutics.

Precision neurotherapeutics represents a transformative paradigm shift from standardized "one-size-fits-all" treatments of neurological, neurodegenera...

Jan 16 2026 41543941
A Mixed Dual-Branch Network for Detecting Cervical Spondylotic Myelopathy and Parkinsonian Syndromes via Gait Analysis.

Cervical spondylotic myelopathy (CSM) and parkinsonian syndromes (PS) present similar motor symptoms, often causing misdiagnosis due to current clinic...

Jan 16 2026 41543967
Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis.

OBJECTIVE: To develop a deep learning algorithm for semiquantification of spinal inflammation in patients with axial spondyloarthritis (SpA). METHODS:...

Jan 16 2026 41545311
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