Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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A comparative study of ChatGPT and DeepSeek in spinal cord injury patient education: Can artificial intelligence "speak" spinal cord injury?

CONTEXT: Large language models (LLMs), such as ChatGPT and DeepSeek, are increasingly used by patients for medical information about their health condition. While several studies have explored ChatGPT's performance in spinal cord injury (SCI)-related queries, no direct comparison between GPT-4o and DeepSeek-V3 has been conducted in this context. METHODS: The five most-searched SCI-related topics c...

Sep 12 2025 40938207

Enhancing interpretability of AI with radiomics-based deep neural network: proof of concept in the classification of Parkinsonian syndromes with 18F-FDG PET imaging.

OBJECTIVE: Interpretability and reproducibility remain major challenges in applying deep neural network (DNN) to neuroimaging-based diagnosis. This study proposes a radiomics-guided dual-channel deep neural network (RDDNN) to improve feature transparency and enhance clinical understanding in the classification of Parkinsonian syndromes. METHODS: In this bi-centric study, we analysed two independen...

Sep 11 2025 40932612
Attention Gated-VGG with deep learning-based features for Alzheimer's disease classification.

BACKGROUND: Alzheimer's disease (AD) is considered to be one of the neurodegenerative diseases with possible cognitive deficits related to dementia in...

Sep 10 2025 40929122
Improvement of an eye disease detection model by using the denoising diffusion implicit model.

With rapid developments in artificial intelligence (AI), the discussion about and applications of generative AI have increased substantially. Generati...

Sep 9 2025 40966958
Multi-modal orthogonal fusion network via cross-layer guidance for Alzheimer's disease diagnosis.

Multi-modal neuroimaging techniques are widely employed for the accurate diagnosis of Alzheimer's Disease (AD). Existing fusion methods typically focu...

Sep 8 2025 40946675
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth.

Increases in impulsivity and negative affect (e.g., neuroticism) are common during adolescence and are both associated with risk for alcohol-use initi...

Sep 5 2025 40913110
Knowledge mapping of biomarkers in amyotrophic lateral sclerosis: a comprehensive bibliometric and visual analysis.

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a severe neurodegenerative disease, and there is currently an urgent need to identify valuable biom...

Sep 4 2025 40905501
Mask-Guided and Fidelity-Constrained Deep Learning Model for Accurate Translation of Brain CT Images to Diffusion MRI Images in Acute Stroke Patients.

The early and precise diagnosis of stroke plays an important role in its treatment planning. Computed Tomography (CT) is utilised as a first diagnosti...

Sep 2 2025 40897831
Prediction of Response to Spinal Cord Stimulation Using Machine Learning Based on Radiomics and Patient-Reported Outcomes.

BACKGROUND AND OBJECTIVES: Chronic pain affects more patients than cancer, diabetes, and heart disease combined, resulting in high morbidity and signi...

Aug 29 2025 40879389
Deep Learning-Based Detection of Papilledema on Retinal Photographs From Handheld Cameras: A Prospective Study.

BACKGROUND: Papilledema and other optic neuropathies are critical findings in neuro-ophthalmology that require timely and accurate diagnosis. This stu...

Aug 28 2025 40867029
Artificial Intelligence Diagnosis of Ocular Motility Disorders From Clinical Videos.

BACKGROUND: Multimodal artificial intelligence (AI) models have recently expanded into video analysis. In ophthalmology, one exploratory application i...

Aug 28 2025 40867040
From resting-state to movement: The role of cortical networks in parkinsonian gait.

BACKGROUND: Gait impairments in Parkinson's disease (PD) arise from disruptions in automatic motor control, requiring compensatory engagement of corti...

Aug 28 2025 40903369
Novel risk calculator predicting long-term survival in pediatric versus adult patients diagnosed with spinal low-grade glioma: a nationwide analysis.

BACKGROUND CONTEXT: Spinal low-grade gliomas (SLGGs) are rare, slow-growing central nervous system tumors affecting both pediatric and adult populatio...

Aug 28 2025 40885265
Unsupervised machine learning to explore inflammation following cardiopulmonary bypass.

IntroductionCardiac surgery with cardiopulmonary bypass (CPB) often induces systemic inflammatory reaction syndrome (SIRS), affecting postoperative ou...

Aug 27 2025 40865539
Robust Quantification of Affected Brain Volume from Computed Tomography Perfusion: A Hybrid Approach Combining Deep Learning and Singular Value Decomposition.

Volumetric estimation of affected brain volumes using computed tomography perfusion (CTP) is crucial in the management of acute ischemic stroke (AIS) ...

Aug 27 2025 40866763
Integrative machine learning approach to risk prediction for dementia and Alzheimer's disease.

Dementia, particularly Alzheimer's disease (AD), presents a growing global health challenge characterized by cognitive decline, behavioral changes, an...

Aug 27 2025 40864401
Evaluating the diagnostic accuracy of AI in ischemic and hemorrhagic stroke: A comprehensive meta-analysis.

Stroke poses a significant health challenge, with ischemic and hemorrhagic subtypes requiring timely and accurate diagnosis for effective management. ...

Aug 25 2025 40854235
Convergence: Multi-omics and AI are reshaping the landscape biomedical research.

This special volume of Biochimica et Biophysica Acta - Molecular Basis of Disease showcases a transformative era in biomedical research, driven by the...

Aug 25 2025 40865690
Flexible wearable medical devices: from material innovations and data processing to intelligent healthcare applications.

BACKGROUND: Flexible wearable medical devices drive healthcare transformation via non-invasive, real-time physiological monitoring and personalized ma...

Aug 22 2025 40850680
AlzhiNet: Traversing from 2D-CNN to 3D-CNN, Towards Early Detection and Diagnosis of Alzheimer's Disease.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with increasing prevalence among the ageing population, necessitating early and a...

Aug 22 2025 40846816
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