Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Lightweight self-attention and deep gated neural network (LSA-DGNet) for multiple neurological disease detection.

Detecting neurological diseases is an important task in modern medicine, for which it is crucial to accurately model the temporal distributions of disease genesis. In prior methodologies, temporal patterns are used in feature effects and limiting assumptions such as proportionate risks. We introduce a new methodology for neural disease diagnosis, known as LSA-DGNet (Lightweight Self-Attention base...

Aug 20 2025 40857843

Proteomic signature of dementia risk in type 2 diabetes.

INTRODUCTION: Type 2 diabetes (T2D) significantly increases dementia risk, yet the molecular mechanisms underlying this association remain unclear. OBJECTIVES: This study aimed to identify protein signatures that distinguish dementia risk in T2D patients, develop a proteomic prediction model, and elucidate biological pathways connecting T2D and dementia. METHODS: We analyzed 2,920 plasma proteins ...

Aug 17 2025 40829688
Automating the Referral of Bone Metastases Patients With and Without the Use of Large Language Models.

BACKGROUND AND OBJECTIVES: Bone metastases, affecting more than 4.8% of patients with cancer annually, and particularly spinal metastases require urge...

Aug 15 2025 40823772
Detection of aging-induced vascular remodeling based on Raman imaging and deep learning.

Vascular aging-related remodeling is a common pathological basis for many chronic diseases, so early detection of physical arterial aging is important...

Aug 15 2025 40848497
Six promising drug repurposing candidates for Alzheimer's disease and their sex-specific mechanisms and efficacy.

Alzheimer's disease is a neurodegenerative disorder that leads to progressive memory loss, cognitive decline, and behavioral changes. Despite ongoing ...

Aug 13 2025 40808416
Machine Learning-Driven Radiomic Profiling of Thalamus-Amygdala Nuclei for Prediction of Postoperative Delirium After STN-DBS in Parkinson's Disease Patients: A Pilot Study.

Postoperative delirium is a common complication following sub-thalamic nucleus deep brain stimulation surgery in Parkinson's disease patients. Postope...

Aug 13 2025 40804595
Predicting Cognition and Affective Changes in Newly Diagnosed Parkinson's Disease Through Longitudinal Data-Driven Clustering.

Background: Although primarily characterised as a motor disorder, Parkinson's Disease (PD) also presents with non-motor symptoms, including cognitive ...

Aug 12 2025 40793816
MiR-138 reprograms dental pulp stem cells into GABAergic neurons via the GATAD2B/MTA3/WNTs axis for stroke treatment.

Prolonged periods of ischemia and hypoxia pose significant challenges to exogenous stem cell transplantation, including minimal cell survival, varied ...

Aug 8 2025 40803231
Fingernail-based metabolomics reveals a stepwise decline in dodecanoic acid associated with Alzheimer's disease progression.

BACKGROUND: Fingernail metabolomics provides a novel, non-invasive platform that captures long-term biochemical fluctuations for identifying reliable ...

Aug 5 2025 40754242
Integrating Time and Frequency Domain Features of fMRI Time Series for Alzheimer's Disease Classification Using Graph Neural Networks.

Accurate and early diagnosis of Alzheimer's Disease (AD) is crucial for timely interventions and treatment advancement. Functional Magnetic Resonance ...

Aug 2 2025 40753124
A machine learning-driven transcriptomic study reveals the key role of Romo1 in reversing central sensitization through stellate ganglion block in migraine: An interventional study based on a recurrent migraine rat model.

OBJECTIVES/BACKGROUND: This study utilized a nitroglycerin (NTG)-induced chronic migraine rat model to explore the therapeutic effects and underlying ...

Aug 1 2025 40747904
Evaluating Dynamic Smile Outcomes of Free Gracilis Muscle Transfer in Pediatric Facial Palsy Using Image-Based Analysis.

BACKGROUND: Facial nerve palsy in children leads to significant functional impairment and facial asymmetry. While free gracilis muscle transfer (FGMT)...

Jul 30 2025 40738135
AI fragment based optimization of saffron and chamomile phytochemicals as aryl hydrocarbon receptor inhibitors for dementia therapy an integrated computational approach.

Dementia represents a rapidly rising global health challenge as a progressive neurodegenerative disease with few options for disease-modifyingtreatmen...

Jul 30 2025 40784071
A Dynamic Machine Learning Model to Predict Angiographic Vasospasm After Aneurysmal Subarachnoid Hemorrhage.

BACKGROUND AND OBJECTIVES: The goal of this study was to develop a highly precise, dynamic machine learning model centered on daily transcranial Doppl...

Jul 24 2025 40704793
Predicting delirium in critically Ill COVID-19 patients using EEG-derived data: a machine learning approach.

Delirium is a severe and common complication among critically ill patients, particularly those with SARS-CoV-2 infection, contributing to increased mo...

Jul 23 2025 40702284
Evaluating predictive performance and generalizability of traditional and artificial intelligence models in predicting surgical site infections postspinal surgery: a systematic review.

BACKGROUND CONTEXT: Surgical site infections (SSIs) are a significant complication following spinal surgery. These infections contribute to increased ...

Jul 14 2025 40669754
Additive Manufacturing of Neuromorphic Systems.

Neuromorphic engineering aims to create brain-inspired computing systems based on synaptic electronic hardware and neural network software. It combine...

Jul 14 2025 40653894
Diagnostic technologies for neuroblastoma.

Neuroblastoma is an aggressive childhood cancer characterised by high relapse rates and heterogenicity. Current medical diagnostic methods involve an ...

Jul 14 2025 40653949
Machine learning approaches for improved understanding of factors associated with history of sport-related concussion.

Sport-related concussion (SRC), which accounts for a significant portion of all mild traumatic brain injuries in the United States, can adversely affe...

Jul 14 2025 40654003
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