Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Recent advances in fluid and tissue-based biomarkers for use in Parkinson's disease.

INTRODUCTION: Parkinson's disease (PD) is a common neurodegenerative disease leading to motor and non-motor disabilities. Broadly accessible fluid- or tissue-based biomarkers will complement neuroimaging and may allow earlier identification and more precise tracking.

Jun 29 2025 40454943

Cognition-Eye-Brain Connection in Alzheimer's Disease Spectrum Revealed by Multimodal Imaging.

BACKGROUND: The connection between cognition, eye, and brain remains inconclusive in Alzheimer's disease (AD) spectrum disorders.

Jun 29 2025 40583127
An FDG-PET-Based Machine Learning Framework to Support Neurologic Decision-Making in Alzheimer Disease and Related Disorders.

BACKGROUND AND OBJECTIVES: Distinguishing neurodegenerative diseases is a challenging task requiring neurologic expertise. Clinical decision support s...

Jun 27 2025 40577677
Artificial Intelligence-Based Detection of Central Retinal Artery Occlusion Within 4.5 Hours on Standard Fundus Photographs.

BACKGROUND: Prompt diagnosis of acute central retinal artery occlusion (CRAO) is crucial for therapeutic management and stroke prevention. However, mo...

Jun 27 2025 40576025
Investigating the benefits of artificial neural networks over linear approaches to BMI decoding.

Brain-machine interfaces (BMI) aim to restore function to persons living with spinal cord injuries by 'decoding' neural signals into behavior. Recentl...

Jun 27 2025 40527337
Artificial Intelligence-Based prediction model for surgical site infection in metastatic spinal disease: a multicenter development and validation study.

BACKGROUND: Treatment of metastatic spinal disease often involves surgical intervention; however, surgical site infections (SSI) pose a great challeng...

Jun 27 2025 40576176
Utility of machine learning algorithms in classification of progressive cognitive impairment in Alzheimer's disease: A retrospective cohort based on China.

BackgroundDistinct risk factors influence Alzheimer's disease (AD) stage stratification, yet effective tools for early diagnosis and prognosis remain ...

Jun 27 2025 40576447
Performance-Recoverable Closed-Loop Neuroprosthetic System.

Soft bioelectronics mechanically comparable to living tissues have driven advances in closed-loop neuroprosthetic systems for the recovery of sensory-...

Jun 27 2025 40576586
Difference between eyes-open and eyes-closed resting state quantitative electroencephalography (qEEG) for predicting cognitive impairment using deep learning.

OBJECTIVE: Electroencephalography (EEG) is a method that offers detailed observations of electrical activities occurring in the brain's cerebral corte...

Jun 27 2025 40577542
Deep Learning-Based Prediction of PET Amyloid Status Using MRI.

BACKGROUND AND PURPOSE: Identifying amyloid-beta (Aβ)-positive patients is essential for Alzheimer's disease (AD) clinical trials and disease-modifyin...

Jun 27 2025 40579043
Movement-responsive deep brain stimulation for Parkinson's disease using a remotely optimized neural decoder.

Deep brain stimulation (DBS) has garnered widespread use as an effective treatment for advanced Parkinson's disease. Conventional DBS (cDBS) provides ...

Jun 27 2025 40579487
Peripheral neural interfaces for reading high-frequency brain signals.

Accurate and robust recording and decoding from the central nervous system (CNS) is essential for advances in human-machine interfacing. Technologies ...

Jun 27 2025 40579488
Plasma lipidomic fingerprinting enables high-accuracy biomarker discovery for Alzheimer's disease: a targeted LC-MRM/MS approach.

Dysregulation of lipid metabolism is increasingly recognized as a key factor in the pathogenesis of Alzheimer's disease (AD). Unfortunately, an accura...

Jun 27 2025 40579668
γ neuromodulations: unraveling biomarkers for neurological and psychiatric disorders.

γ neuromodulation has emerged as a promising strategy for addressing neurological and psychiatric disorders, particularly in regulating executive and ...

Jun 27 2025 40571935
The class imbalance problem in automatic localization of the epileptogenic zone for epilepsy surgery: a systematic review.

Accurate localization of the epileptogenic zone (EZ) is crucial for epilepsy surgery, but the class imbalance of epileptogenic vs. non-epileptogenic e...

Jun 26 2025 40489993
Impact of Artificial Intelligence on the Timing of Recurrent Laryngeal Nerve Recognition during Robot-Assisted Minimally Invasive Esophagectomy.

BACKGROUND: As a first step to prevent recurrent laryngeal nerve (RLN) palsy, we have developed an artificial intelligence (AI)-based anatomical recog...

Jun 26 2025 40569356
Unraveling the role of perineural invasion in cancer progression across multiple tumor types.

Perineural invasion (PNI) refers to the infiltration of tumor cells into the connective tissue of nerves and is increasingly recognized as a pathologi...

Jun 26 2025 40569482
Predicting Retinal Nerve Fiber Layer Thickness From Ocular Hypertension Treatment Study Optic Disc Photographs.

IMPORTANCE: Deep learning predictions of retinal nerve fiber layer (RNFL) thickness derived from optic disc photographs may help to determine risk for...

Jun 26 2025 40569586
On the usage of artificial intelligence in leprosy care: A systematic literature review.

Leprosy, or Hansen's disease, is a Neglected Tropical Disease (NTD) caused by Mycobacterium leprae that mainly affects the skin and peripheral nerves,...

Jun 26 2025 40570262
Development and validation of a combined clinical and MRI-based biomarker model to differentiate mild cognitive impairment from mild Alzheimer's disease.

BACKGROUND: Two of the most common complaints seen in neurology clinics are Alzheimer's disease (AD) and mild cognitive impairment (MCI), characterize...

Jun 26 2025 40575445
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