Radiology

Nuclear Medicine

Latest AI and machine learning research in nuclear medicine for healthcare professionals.

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SMGDiff: step mapping generalized diffusion model for efficient noise reduction in cardiac-gated myocardial perfusion SPECT images.

BACKGROUND: Improving the image quality of cardiac gating myocardial perfusion single-photon emission computed tomography (CG MP-SPECT) is crucial for accurate diagnosis. Diffusion model (DM) has recently shown promise in MP-SPECT image denoising, but traditional DM typically require extensive computational resources and prolonged processing times. The study aims to develop and evaluate a lightwei...

Jan 17 2026 41546843

Biomarker discovery in Lennox-Gastaut syndrome: Advances and challenges in electrophysiological, genetic, neuroimaging, and neuroinflammatory approaches.

In Lennox-Gastaut Syndrome (LGS), a severe developmental and epileptic encephalopathy, the absence of validated biomarkers limits our ability to detect disease early, predict outcomes, and guide treatment strategies. This review synthesizes advances in biomarker research spanning electrophysiological, genetic, neuroimaging, and neuroinflammatory domains. Interictal electroencephalography (EEG) pat...

Jan 17 2026 41548392
Multisequence MRI Enables High-Fidelity FDG-PET Synthesis for Epilepsy Using GANs.

BACKGROUND: FDG-PET aids presurgical epilepsy evaluation but is limited by access and radiation exposure. PURPOSE: To evaluate synthetic FDG-PET gener...

Jan 16 2026 41542825
Sex Differences in Alzheimer's Disease: A Systematic Review of Two Decades of Neuroimaging Research.

OBJECTIVES: Given the heterogeneous nature of Alzheimer's Disease (AD) and its higher prevalence in females, it is crucial to understand sex-related d...

Jan 16 2026 41546373
Generalizable Deep Learning for Prostate Cancer Risk Stratification: Multicenter Study Integrating 18F-PSMA-1007 PET/CT and mpMRI.

BACKGROUND: Prostate cancer is the second most common cancer in men, with rising mortality rates necessitating precise risk stratification. High-invas...

Jan 16 2026 41547629
Deep Learning Analysis Based on Dual-energy CT-Derived Iodine Map for Predicting PD-L1 Expression in Gastric Cancer: A Multicenter Study.

RATIONALE AND OBJECTIVES: PD-L1 expression is a critical biomarker in guiding immunotherapy for gastric cancer (GC). This study aims to investigate th...

Jan 16 2026 41547630
Artificial Intelligence in Pleural Diseases: Current Applications and Next Steps.

Pleural diseases pose a significant burden on healthcare systems due to diagnostic challenges and high costs. Artificial intelligence (AI) has the pot...

Jan 15 2026 41536177
Stratifying amyloid burden in early Alzheimer's disease using cascaded attention-guided vision transformer using [¹⁸F]Florbetapir PET.

OBJECTIVES: This study aims to develop a deep learning model to assist physicians in accurately classifying negative, equivocal, and positive β-amyloi...

Jan 15 2026 41537783
Interpretable machine learning framework for predicting the reactivity of trifluoromethylating reagents.

The incorporation of a trifluoromethyl (-CF3) group into organic frameworks profoundly influences their physicochemical and biological properties, mak...

Jan 14 2026 41439279
Detection of parkinson's disease with neuroimaging modalities using machine learning and artificial intelligence: a systematic review.

The application of machine learning (ML) and artificial intelligence (AI) algorithms in medical imaging is an emerging area of interest, particularly ...

Jan 14 2026 41530502
Deep learning-based restoration of PET images from a dual-panel breast dedicated scanner.

Positron Emission Tomography (PET) is important for breast cancer diagnosis and monitoring, but high costs restrict access. Dual-panel scanners can re...

Jan 14 2026 41535178
Multicenter evaluation of interpretable AI for coronary artery disease diagnosis from PET biomarkers.

Positron emission tomography (PET)/computed tomography (CT) for myocardial perfusion imaging (MPI) provides multiple imaging biomarkers, often evaluat...

Jan 14 2026 41535345
Machine learning-assisted Raman spectroscopy for non-destructive analysis of crude palm oil quality.

Quality assessment of crude palm oil remains a critical challenge globally, particularly in resource-poor areas where traditional methods are time-con...

Jan 14 2026 41535673
CT-free attenuation and scatter correction of [11C]CFT brain PET using a Bi-directional matching network.

Quantitative PET imaging requires accurate attenuation and scatter correction (ASC), but the standard CT-based method introduces additional radiation ...

Jan 13 2026 41539466
Quality of Life and Decision Regret Risk in Graves' Disease After Radioactive Iodine Therapy: A Prospective Cohort Study.

OBJECTIVE: To identify pre-treatment determinants of hypothyroidism and decision regret (DR) following radioiodine (RAI) therapy in Graves' disease (G...

Jan 12 2026 41524231
Non-invasive Prediction of CYP11B2-Defined Subtypes in Primary Aldosteronism Using 18F-Pentixafor PET/CT and Machine Learning.

PURPOSE: This study aims to develop and validate an interpretable machine learning model that integrates clinical data, radiomics, and deep learning (...

Jan 12 2026 41530023
An Ensemble Learning Artificial Intelligence Model for Alzheimer's Disease Detection Using OCT.

PURPOSE: There has been significant progress in detecting Alzheimer's disease (AD) using retinal imaging. We developed an ensemble learning-based deep...

Jan 10 2026 41717239
MRI-to-PET synthesis via deep learning for amyloid-β quantification in Alzheimer's disease.

OBJECTIVES: Amyloid-β (Aβ) PET is crucial for diagnosing and monitoring Alzheimer's disease (AD), but its high cost and radiation exposure limit its u...

Jan 7 2026 41495456
QSAR Prediction of BBB Permeability Based on Machine Learning upon PETBD: A Novel Data Set of PET Tracers.

Assessing small-molecule blood-brain barrier permeability is laborious, yet critical in drug development. Quantitative prediction models are hindered ...

Jan 6 2026 41494098
Deep learning-guided attenuation and scatter correction of 99mTc-MAA SPECT images: towards quantitative analysis in 90Y-SIRT.

PURPOSE: This study aimed to develop deep learning (DL) models for CT-free attenuation correction and Monte Carlo-based scatter correction in 99mTc-ma...

Jan 5 2026 41489766
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