Radiology

Nuclear Medicine

Latest AI and machine learning research in nuclear medicine for healthcare professionals.

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Generalizable Deep Learning for Prostate Cancer Risk Stratification: Multicenter Study Integrating 18F-PSMA-1007 PET/CT and mpMRI.

BACKGROUND: Prostate cancer is the second most common cancer in men, with rising mortality rates necessitating precise risk stratification. High-invasive biological features-specifically International Society of Urological Pathology (ISUP) grade, extracapsular extension (EPE), and positive surgical margins (PSM)-are critical for guiding treatment but are difficult to detect due to tumor heterogene...

Jan 16 2026 41547629

Deep Learning Analysis Based on Dual-energy CT-Derived Iodine Map for Predicting PD-L1 Expression in Gastric Cancer: A Multicenter Study.

RATIONALE AND OBJECTIVES: PD-L1 expression is a critical biomarker in guiding immunotherapy for gastric cancer (GC). This study aims to investigate the value of deep learning analysis based on dual-energy CT-derived iodine map for predicting the level of PD-L1 expression in GC. METHODS: A total of 267 GC patients who underwent gastrectomy and preoperative dual-energy CT from multiple centers were ...

Jan 16 2026 41547630
Artificial Intelligence in Pleural Diseases: Current Applications and Next Steps.

Pleural diseases pose a significant burden on healthcare systems due to diagnostic challenges and high costs. Artificial intelligence (AI) has the pot...

Jan 15 2026 41536177
Stratifying amyloid burden in early Alzheimer's disease using cascaded attention-guided vision transformer using [¹⁸F]Florbetapir PET.

OBJECTIVES: This study aims to develop a deep learning model to assist physicians in accurately classifying negative, equivocal, and positive β-amyloi...

Jan 15 2026 41537783
Interpretable machine learning framework for predicting the reactivity of trifluoromethylating reagents.

The incorporation of a trifluoromethyl (-CF3) group into organic frameworks profoundly influences their physicochemical and biological properties, mak...

Jan 14 2026 41439279
Detection of parkinson's disease with neuroimaging modalities using machine learning and artificial intelligence: a systematic review.

The application of machine learning (ML) and artificial intelligence (AI) algorithms in medical imaging is an emerging area of interest, particularly ...

Jan 14 2026 41530502
Deep learning-based restoration of PET images from a dual-panel breast dedicated scanner.

Positron Emission Tomography (PET) is important for breast cancer diagnosis and monitoring, but high costs restrict access. Dual-panel scanners can re...

Jan 14 2026 41535178
Multicenter evaluation of interpretable AI for coronary artery disease diagnosis from PET biomarkers.

Positron emission tomography (PET)/computed tomography (CT) for myocardial perfusion imaging (MPI) provides multiple imaging biomarkers, often evaluat...

Jan 14 2026 41535345
Machine learning-assisted Raman spectroscopy for non-destructive analysis of crude palm oil quality.

Quality assessment of crude palm oil remains a critical challenge globally, particularly in resource-poor areas where traditional methods are time-con...

Jan 14 2026 41535673
CT-free attenuation and scatter correction of [11C]CFT brain PET using a Bi-directional matching network.

Quantitative PET imaging requires accurate attenuation and scatter correction (ASC), but the standard CT-based method introduces additional radiation ...

Jan 13 2026 41539466
Quality of Life and Decision Regret Risk in Graves' Disease After Radioactive Iodine Therapy: A Prospective Cohort Study.

OBJECTIVE: To identify pre-treatment determinants of hypothyroidism and decision regret (DR) following radioiodine (RAI) therapy in Graves' disease (G...

Jan 12 2026 41524231
Non-invasive Prediction of CYP11B2-Defined Subtypes in Primary Aldosteronism Using 18F-Pentixafor PET/CT and Machine Learning.

PURPOSE: This study aims to develop and validate an interpretable machine learning model that integrates clinical data, radiomics, and deep learning (...

Jan 12 2026 41530023
An Ensemble Learning Artificial Intelligence Model for Alzheimer's Disease Detection Using OCT.

PURPOSE: There has been significant progress in detecting Alzheimer's disease (AD) using retinal imaging. We developed an ensemble learning-based deep...

Jan 10 2026 41717239
MRI-to-PET synthesis via deep learning for amyloid-β quantification in Alzheimer's disease.

OBJECTIVES: Amyloid-β (Aβ) PET is crucial for diagnosing and monitoring Alzheimer's disease (AD), but its high cost and radiation exposure limit its u...

Jan 7 2026 41495456
QSAR Prediction of BBB Permeability Based on Machine Learning upon PETBD: A Novel Data Set of PET Tracers.

Assessing small-molecule blood-brain barrier permeability is laborious, yet critical in drug development. Quantitative prediction models are hindered ...

Jan 6 2026 41494098
Deep learning-guided attenuation and scatter correction of 99mTc-MAA SPECT images: towards quantitative analysis in 90Y-SIRT.

PURPOSE: This study aimed to develop deep learning (DL) models for CT-free attenuation correction and Monte Carlo-based scatter correction in 99mTc-ma...

Jan 5 2026 41489766
Deep learning image reconstruction improves 40 keV virtual monoenergetic image quality in rectal cancer.

BACKGROUND: Accurate preoperative evaluation of rectal cancer is essential for staging and treatment planning. Low-energy virtual monoenergetic imagin...

Jan 3 2026 41520415
Machine learning for automated differentiation of parkinson's disease and its mimics using ¹²³I-mIBG scintigraphy: insights from a multicentre real-world cohort (ITA-mIBG study).

PURPOSE: To assess machine learning (ML) classifiers trained on harmonised multicentre ¹²³I-mIBG planar scintigraphy for differentiating Parkinson's d...

Jan 2 2026 41483307
Preoperative prediction of lymph node metastasis and prognosis in gastric cancer patients: A machine learning model based on 18F-FDG metabolic parameters.

OBJECTIVE: To construct and validate a model for predicting lymph node metastasis (LNMs) of gastric cancer (GC) based on 18F-FDG PET/CT multi-paramete...

Jan 2 2026 41485604
SupReMix: Supervised contrastive learning for medical imaging regression with mixup.

In medical image analysis, regression plays a critical role in computer-aided diagnosis. It enables quantitative measurements such as age prediction f...

Dec 31 2025 41520605
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