Nuclear Medicine

Photon-counting detector computed tomography in thoracic oncology: revolutionizing tumor imaging through precision and detail.

Photon-counting detector computed tomography (PCD-CT) is an emerging imaging technology that promises to overcome the limitations of conventional energy-integrating detector (EID)-CT, particularly in thoracic oncology. This narrative review summarizes technical advances and clinical applications of PCD-CT in the thorax with emphasis on spatial resolution, dose-image-quality balance, and intrinsic ...

A New Method of Modeling the Multi-stage Decision-Making Process of CRT Using Machine Learning with Uncertainty Quantification.

Current machine learning-based (ML) models usually attempt to utilize all available patient data to predict patient outcomes while ignoring the associated cost and time for data acquisition. The purpose of this study is to create a multi-stage ML model to predict cardiac resynchronization therapy (CRT) response for heart failure (HF) patients. This model exploits uncertainty quantification to reco...

Artificial intelligence-assisted PET imaging for predicting neoadjuvant chemotherapy response in breast cancer: a systematic review and meta-analysis.

PURPOSE: This study aims to evaluate the performance of artificial intelligence (AI)-assisted PET imaging in predicting neoadjuvant chemotherapy (NAC)...

Habitat-aware radiomics and adaptive 2.5D deep learning predict treatment response and long-term survival in ESCC patients undergoing neoadjuvant chemoimmunotherapy.

PURPOSE: Current radiomic approaches inadequately resolve spatial intratumoral heterogeneity (ITH) in esophageal squamous cell carcinoma (ESCC), limit...

Data fusion of medical imaging in neurological disorders.

Medical imaging plays a crucial role in the accurate diagnosis and prognosis of various medical conditions, with each modality offering unique and com...

Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response.

Preclinical evidence points to disturbances in neural networks in psychosis involving interrelations between dopaminergic-, GABAergic- and glutamaterg...

Enhancing interpretability of AI with radiomics-based deep neural network: proof of concept in the classification of Parkinsonian syndromes with 18F-FDG PET imaging.

OBJECTIVE: Interpretability and reproducibility remain major challenges in applying deep neural network (DNN) to neuroimaging-based diagnosis. This st...

Artificial intelligence-assisted assessment of metabolic response to tebentafusp in metastatic uveal melanoma: a long axial field-of-view [18F]FDG PET/CT study.

PURPOSE: Tebentafusp has emerged as the first systemic therapy to significantly prolong survival in treatment-naïve HLA-A*02:01 + patients with unrese...

A Pilot Study on Quantitative Accuracy and Radiomic Feature Stability of Deep Progressive Learning Reconstruction in NSCLC PET.

Deep progressive learning reconstruction (DPR) is a novel deep learning-based algorithm for PET imaging, yet its impact on quantitative metrics and ra...

An AI-Based Solution for Denoising Fast-Acquisition [18F]FDG PET: Clinical Feasibility and Quantitative Assessment.

Benefits in patient comfort, efficiency, and sustainability can come from reducing positron emission tomography (PET) scan's acquisition duration. Thi...

Digital versus analogue PET in parathyroid imaging: comparison of PET metrics and machine learning-based characterisation of hyperfunctioning lesions (the DIGI-PET study).

PURPOSE: To compare PET-derived metrics between digital and analogue PET/CT in hyperparathyroidism, and to assess whether machine learning (ML) applie...

Spatial imaging features derived from SUVmax location in resectable NSCLC are associated with tumor aggressiveness.

PURPOSE: Accurate non-invasive prediction of histopathologic invasiveness and recurrence risk remains a clinical challenge in resectable non-small cel...

Development and validation of a transformer-based deep learning model for predicting distant metastasis in non-small cell lung cancer using 18FDG PET/CT images.

BACKGROUND: This study aimed to develop and validate a hybrid deep learning (DL) model that integrates convolutional neural network (CNN) and vision t...

AI Prognostication in Nonsmall Cell Lung Cancer: A Systematic Review.

The systematic literature review was performed on the use of artificial intelligence (AI) algorithms in nonsmall cell lung cancer (NSCLC) prognosticat...

The role of neuro-imaging in multiple system atrophy.

Neuroimaging plays a crucial role in diagnosing multiple system atrophy and monitoring progressive neurodegeneration in this fatal disease. Advanced M...

Effect of data-driven motion correction for respiratory movement on lesion detectability in PET-CT: a phantom study.

PURPOSE: While data-driven motion correction (DDMC) techniques have proven to enhance the visibility of lesions affected by motion, their impact on ov...

Machine learning to identify suitable boundaries for band-pass spectral analysis of dynamic [ C]Ro15-4513 PET scan and voxel-wise parametric map generation.

BACKGROUND: Spectral analysis is a model-free PET quantification technique that treats the time-space signal as an impulse response to a bolus injecti...

Limited-angle SPECT image reconstruction using deep image prior.

. In single-photon emission computed tomography (SPECT) image reconstruction, limited-angle conditions lead to a loss of frequency components, which d...

Differentiated thyroid cancer and positron emission computed tomography: when, how and why?

INTRODUCTION: Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has become an indispensable tool in oncology, offering ...

Deep supervised transformer-based noise-aware network for low-dose PET denoising across varying count levels.

BACKGROUND: Reducing radiation dose from PET imaging is essential to minimize cancer risks; however, it often leads to increased noise and degraded im...