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Nuclear Medicine

Latest AI and machine learning research in nuclear medicine for healthcare professionals.

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A rapid total-body PET imaging approach for pediatric patients using non-attenuation-corrected PET scans.

BACKGROUND: Pediatric lymphoma patients undergo multiple 18F-FDG PET/CT examinations for staging and response assessment, raising concerns about cumulative radiation dose, particularly from the CT component. We propose SnapPET, a CT-sparing deep learning-based framework that uses 2D ultra-short non-attenuation-corrected (NAC) PET (Maximum intensity projection) MIP images to generate 2D high-qualit...

May 22 2026 42171886

Simultaneous partial volume correction and denoising of brain PET images, using transformers and transfer learning.

BACKGROUND: Positron emission tomography (PET) is a key tool for quantitative brain imaging, but its image quality and quantitative reliability are strongly dependent on injected radiotracer activity and acquisition time. Reducing injected dose or acquisition time lowers radiation exposure but increases image noise, while partial volume effects (PVE) further degrade signal accuracy, especially in ...

May 22 2026 42171947
Can LLMs Turn French PET/CT Narrative Reports into Structured Knowledge?

This study evaluates large language models (LLMs) for information extraction from French PET/CT reports related to cognitive impairment, focusing on d...

May 21 2026 42174838
Acquisition time/dose reduction in pediatric PET imaging using patch-based deep learning.

BACKGROUND: Deep learning (DL)-based denoising methods have shown promise for reducing radiation dose and/or acquisition time in pediatric PET imaging...

May 21 2026 42165901
FDG PET for cardiac sarcoidosis: Protocol optimization, quantification, pitfalls, and multimodality imaging integration.

Cardiac sarcoidosis (CS) is a clinically heterogeneous disorder associated with significant morbidity and mortality, including heart failure, conducti...

May 21 2026 42168054
The Brain Imaging and Neurophysiology Dataset of large-scale multimodal neural data.

The Brain Imaging and Neurophysiology Dataset (BIND) represents one of the largest multi-institutional, multimodal, clinical neuroimaging repositories...

May 21 2026 42168237
Innovations in pediatric imaging: a scoping review of the past decade with case illustrations.

BACKGROUND: Imaging plays a fundamental and increasing role in the diagnostic work-up of pediatric patients. Non-invasive imaging methods include ultr...

May 21 2026 42168717
Prognostic Significance of Baseline 18F-FDG PET/CT Parameters in Combination with an Artificial Intelligence-Based Pleural Effusion Segmentation Model for Malignant Pleural Effusion.

OBJECTIVES: We aimed to use an artificial intelligence (AI)-based pleural effusion segmentation model on baseline 18F-FDG positron emission tomography...

May 20 2026 42162960
Evaluation of 2D and 3D nnU-Net models with two-label and three-label strategies for automatic segmentation and total metabolic tumor volume estimation of metastatic differentiated thyroid carcinoma on FDG-PET/CT.

PURPOSE: To evaluate the segmentation performance and total metabolic tumor volume (TMTV) prediction accuracy of 2D and 3D nnU-Net models under two-la...

May 20 2026 42159908
An interpretable machine learning model integrating [18F]FDG PET/CT radiomics and clinical features for predicting perforation following chemotherapy in gastrointestinal lymphoma: a multicenter study.

BACKGROUND: Perforation following chemotherapy in gastrointestinal lymphoma (PFCGL) is a rare but severe and life-threatening complication. Early pre-...

May 19 2026 42151619
Multimodal Artificial Intelligence for Early Detection and Precision Management of Inflammatory and Infiltrative Cardiomyopathies.

BACKGROUND: Inflammatory and infiltrative cardiomyopathies, including cardiac sarcoidosis, transthyretin amyloidosis, and autoimmune myocarditis, are ...

May 18 2026 42155787
Automatic computation of breast cancer biomarkers from multiple [Formula: see text] F-FDG PET image segmentation.

Neoadjuvant chemotherapy is a standard clinical practice for tumor downsizing in breast cancer, with [Formula: see text]F-FDG Positron Emission Tomogr...

May 18 2026 42151250
Assessing the suitability of automated registration and segmentation for dosimetry calculations in SIRT treatment planning.

BACKGROUND: Selective internal radiation therapy (SIRT) increasingly relies on accurate magnetic resonance imaging (MRI) to computed tomography (CT) r...

May 17 2026 42143172
A workflow utilizing general-purpose large language models for efficient structuring and data mining of bone scintigraphy narratives.

Whole-body bone scintigraphy is pivotal for skeletal evaluation in oncological monitoring, yet the unstructured nature of clinical reports impedes eff...

May 17 2026 42144441
An interpretable PET/CT-based radiomic-clinical model for predicting bone marrow involvement in follicular lymphoma: comparison of pelvic and spine-pelvis VOI frameworks.

PURPOSE: To investigate the feasibility of non-invasively identifying bone marrow involvement (BMI) in follicular lymphoma (FL) using baseline 18F-FDG...

May 16 2026 42142271
MedNext-Insight Model for Automated Metabolic Tumor Volume Delineation on Computed Tomography and Prognostic Value in Nasopharyngeal Carcinoma.

PURPOSES: To develop a deep learning model for automated metabolic tumor volume (MTV) delineation on routine computed tomography (CT) without positron...

May 16 2026 42144163
Image-derived input functions for [18F]LW223 and [18F]SynVesT-1 PET in the rodent determined using an autoencoder (IDIF-AE).

Objective.Quantitative analysis of dynamic positron emission tomography (PET) scans requires knowledge of the arterial input function (AIF). Existing ...

May 15 2026 42140281
Influence of scintillation light confinement on depth-of-interaction measurement performance in a single-Ended readout PET detector.

Continuous depth-of-interaction (cDOI) detectors enable single-ended readout in positron emission tomography (PET) by encoding the interaction depth i...

May 15 2026 42140287
Adaptive patch sampling and location-aware reasoning for whole body PET-CT multi-organ segmentation.

Patch-wise learning is a common strategy for training neural networks on large-scale dense prediction problems, yet existing approaches assume uniform...

May 15 2026 42141028
CT-less TOF PET: challenges and innovations for quantitative imaging.

A decade has passed since the groundbreaking work by Defrise et al. (2012), which demonstrated that TOF PET imaging is self-correcting for a variety o...

May 14 2026 42134409
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