Obesity

Validating the Health Benefits of Coffee Berry Pulp Extracts in Mice with High-Fat Diet-Induced Obesity and Diabetes.

The effects of coffee ( L.) berry pulp extracts (CBP extracts) on the improvement of diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD) were evaluated using various in vitro antioxidant activity assays and through a high-fat diet-induced mild diabetic obese mouse model. After an 84-day oral administration of CBP extracts (400-100 mg/kg), bioactivities were evaluated. The in vitro ana...

Implementation of artificial intelligence models in magnetic resonance imaging with focus on diagnosis of rheumatoid arthritis and axial spondyloarthritis: narrative review.

Early diagnosis in rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) is essential to initiate timely interventions, such as medication and lifestyle changes, preventing irreversible joint damage, reducing symptoms, and improving long-term outcomes for patients. Since magnetic resonance imaging (MRI) of the wrist and hand, in case of RA and MRI of the sacroiliac joints (SIJ) in case of ...

Artificial intelligence scoring of liver biopsies in a phase II trial of semaglutide in nonalcoholic steatohepatitis.

BACKGROUND AND AIMS: Artificial intelligence-powered digital pathology offers the potential to quantify histological findings in a reproducible way. T...

Effects of grape juice intake on the cell migration properties in overweight women: Modulation mechanisms of cell migration in vitro by delphinidin-3-O-glucoside.

Overweight and obesity are typical conditions of chronic low-intensity systemic inflammatory responses, and both have become more common in recent dec...

Public Awareness of Obesity as a Risk Factor for Cancer in Central Saudi Arabia: Feasibility of ChatGPT as an Educational Intervention.

BACKGROUND: While the link between obesity and chronic diseases such as diabetes and cardiovascular disorders is well-documented, there is a growing b...

Population-Based Artificial Intelligence Assessment of Relationship Between the Risk Factors for Diabetic Retinopathy in Indian Population.

PURPOSE: Risk factors (RFs), like 'body mass index (BMI),' 'age,' and 'gender' correlate with Diabetic Retinopathy (DR) diagnosis and have been widely...

A single session of strength training changed plasma levels of resistin, but not leptin in overweight and obese men.

Obesity has a complex multifactorial etiology and is characterized by excessive accumulation of adipose tissue. Visceral adipose tissue has deleteriou...

Multiple generation distinct toxicant exposures induce epigenetic transgenerational inheritance of enhanced pathology and obesity.

Three successive multiple generations of rats were exposed to different toxicants and then bred to the transgenerational F5 generation to assess the i...

European validation of an image-derived AI-based short-term risk model for individualized breast cancer screening-a nested case-control study.

BACKGROUND: Image-derived artificial intelligence (AI)-based risk models for breast cancer have shown high discriminatory performances compared with c...

An accurate aging clock developed from large-scale gut microbiome and human gene expression data.

Accurate measurement of the biological markers of the aging process could provide an "aging clock" measuring predicted longevity and enable the quanti...

AI and semantic ontology for personalized activity eCoaching in healthy lifestyle recommendations: a meta-heuristic approach.

BACKGROUND: Automated coaches (eCoach) can help people lead a healthy lifestyle (e.g., reduction of sedentary bouts) with continuous health status mon...

ADHD/CD-NET: automated EEG-based characterization of ADHD and CD using explainable deep neural network technique.

UNLABELLED: In this study, attention deficit hyperactivity disorder (ADHD), a childhood neurodevelopmental disorder, is being studied alongside its co...

Weight change in chronic kidney disease: Association with mortality and kidney function.

BACKGROUND: Excess body weight is a risk factor for the progression of chronic kidney disease (CKD), but weight loss in CKD has been associated with h...

Predicting Psoriatic Arthritis in Psoriasis Patients - A Swiss Registry Study.

BACKGROUND: Psoriatic arthritis (PsA) is a prevalent comorbidity among patients with psoriasis, heavily contributing to their burden of disease, usual...

Proprotein convertase subtilisin/kexin type 9 (PCSK9) as a marker of coronary lesion severity in stable coronary artery disease (CAD) patients.

Coronary artery disease (CAD) remains a significant global health concern with considerable high morbidity and mortality and its development is influe...

Can ChatGPT provide appropriate meal plans for NCD patients?

OBJECTIVES: Dietary habits significantly affect health conditions and are closely related to the onset and progression of non-communicable diseases (N...

Chronic kidney disease and Charlson comorbidity index predict complications after robot-assisted radical cystectomy: A single-center study in Japan.

OBJECTIVES: To investigate preoperative patient factors that may predict the occurrence of perioperative complications following robot-assisted radica...

Understanding the need for digital twins' data in patient advocacy and forecasting oncology.

Digital twins are made of a real-world component where data is measured and a virtual component where those measurements are used to parameterize comp...

Impact of Visceral Fat Area on Intraoperative Complexity and Surgical Approach Decision for Robot-Assisted Partial Nephrectomy: A Comparative Analysis with BMI.

BACKGROUND Optimizing surgical approaches for robot-assisted partial nephrectomy (RAPN) is vital for better patient outcomes. This retrospective study...

PINK1 dominated mitochondria associated genes signature predicts abdominal aortic aneurysm with metabolic syndrome.

Abdominal aortic aneurysm (AAA) is typically asymptomatic but a devastating cardiovascular disorder, with overall mortality exceeding 80 % once it rup...