Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Multimodal Rehabilitation for Advanced Cancer Pain: a Narrative Review of Emerging Nonpharmacological Strategies.

PURPOSE OF REVIEW: This narrative review aims to explore research advances in multimodal rehabilitation for advanced cancer pain, with a primary focus on nonpharmacological intervention approaches, to offer comprehensive treatment strategies for cancer pain management. RECENT FINDINGS: While the WHO analgesic regimen holds a central position, long-term medication use may lead to drug resistance an...

Jan 24 2026 41579249

Automatic and accurate auxiliary detection of lung cancer pathological classification based on novel lightweight deep learning model.

BACKGROUND: Lung cancer is one of the major cancers worldwide, and rapid, accurate diagnosis is crucial for subsequent treatment and management. Currently, pathological subtype detection requires clinical experts to invest significant time and effort, making the development of automatic, efficient detection models essential. METHODS: This study developed a novel deep learning model named BreezeNet...

Jan 24 2026 41579280
Breast cancer frontiers: mapping molecular signals, intelligent diagnostics, and adaptive therapies.

Breast cancer continues to be a significant worldwide health concern, requiring ongoing improvements in early detection, therapeutic approaches, and c...

Jan 24 2026 41579281
Research on the molecular mechanism of celastrol targeting CTNNB1/STAT3 to inhibit uveal melanoma based on network pharmacology and multi-omics analysis.

Uveal melanoma (UM) is among the most prevalent intraocular malignant tumors worldwide. Celastrol exhibits broad-spectrum anticancer properties; howev...

Jan 24 2026 41580492
DANEELpath open source digital analysis tools for histopathological research in neuroblastoma models.

Despite the considerable expansion of bioimage analysis as a subfield of biomedical sciences, there is an ongoing need for comprehensive image analysi...

Jan 24 2026 41580539
Deep learning for malignancy and tumor origin prediction using cytology or histopathology whole slide images.

Pleural and ascitic cytology is essential for diagnosing metastatic cancer and predicting tumor origin, yet microscopic observation alone often leads ...

Jan 24 2026 41580547
The impact of AI on modern oncology from early detection to personalized cancer treatment.

Artificial intelligence (AI) is quickly becoming a revolutionary and game-changing tool in modern oncology, with promising uses in early diagnosis and...

Jan 24 2026 41580561
ProteoBoostR: an interactive framework for supervised machine learning in clinical proteomics.

BACKGROUND: Mass spectrometry-based proteomics enables high-throughput quantification of thousands of proteins in clinical samples, fueling biomarker ...

Jan 24 2026 41580610
CT-based radiomics nomogram for preoperative prediction of Ki-67 in lung neuroendocrine neoplasms: a multicenter study.

OBJECTIVE: Lung neuroendocrine neoplasms (L-NENs) are increasingly recognized, yet reliable preoperative assessment of the Ki-67 proliferation index r...

Jan 24 2026 41580638
Utilization of machine learning algorithms for the identification of the RLN associated prognostic model and feature biomarkers of RLN-related subtypes in breast cancer.

BACKGROUND: Breast cancer (BC) is the most common malignancy afflicting women worldwide, yet the role of relaxin-related genes (RLN) in BC progression...

Jan 24 2026 41581316
Recent advances in redox-responsive polysaccharide-based nanostructures for cancer therapy.

Conventional tumor chemotherapy faces limitations including drug resistance, high toxicity, non-selectivity, and side effects. Nano-drug delivery syst...

Jan 23 2026 41713980
Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review).

Lung cancer remains a significant global health challenge, with metastatic progression being the leading driver of mortality. Organoid technology prov...

Jan 23 2026 41574717
Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review).

The management of nasopharyngeal carcinoma (NPC), a malignancy with pronounced geographic prevalence in Southeast Asia, is undergoing a paradigm shift...

Jan 23 2026 41574726
Influencing Factors for Postembolization Fever in Patients Undergoing Transarterial Chemoembolization Based on Machine Learning: A Retrospective Study.

Although there is no framework for prediction models for postembolization fever, potential influencing factors include demographic, clinical, laborato...

Jan 23 2026 41574469
A novel cervical image recognition framework based on feature cognitive enhancement for improved performance.

Cervical cancer ranks as the fourth most prevalent cancer among women worldwide. Early diagnosis facilitates timely intervention and treatment. Tradit...

Jan 23 2026 41574558
Novel bayesian nonparametric unsupervised learning approach to precision symptom management in cancer survivors: a re-analysis of a comparative effectiveness trial.

Cancer survivors often experience multiple cooccurring symptoms such as insomnia, pain, fatigue, and anxiety; yet conventional analyses in symptom sci...

Jan 23 2026 41575714
Prediction of 12-Week Remission in Patients With Depressive Disorder Using Reasoning-Based Large Language Models: Model Development and Validation Study.

BACKGROUND: Depressive disorder affects over 300 million people globally, with only 30% to 40% of patients achieving remission with initial antidepres...

Jan 23 2026 41576265
Identification and Localization of Breast Tumor Components via a Convolutional Neural Network Based on High-Frequency Ultrasound Combined With Histopathologic Registration: Prospective Study.

BACKGROUND: Given the highly heterogeneous biology of breast cancer, a more effective noninvasive diagnostic tool that unravels microscopic histopatho...

Jan 23 2026 41576341
Sorafenib nanomedicine in HCC: nano-bio interactions and combination therapies.

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, with systemic therapies offering only limited benefit. S...

Jan 23 2026 41578333
Prediction of renal cell carcinoma: Development and validation of machine learning model.

Renal cell carcinoma (RCC) is the leading cause of urinary system morbidity and mortality. Early identification is crucial for improving RCC patient o...

Jan 23 2026 41578457
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