Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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A Clinically Annotated Transcriptomic Atlas of Nervous System Tumors.

BACKGROUND: While DNA methylation signatures are distinct across nervous system neoplasms, it has not been comprehensively demonstrated whether transcriptomic signatures exhibit similar uniqueness. Additionally, no large-scale dataset for comparative gene expression analyses exists. This study addresses these knowledge and resource gaps.

May 27 2025 40423244

Future Perspectives of Liver Research in the Asia-Pacific Region: Focus on Hepatitis B and C.

The Asia-Pacific region faces serious liver health challenges, primarily because of the comparatively high prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, as well as the increasing disease burden of metabolic-associated steatotic liver disease (MASLD), alcohol-associated liver disease, and hepatocellular carcinoma (HCC). Despite MASLD being the cause with the highest ...

May 27 2025 40423265
Vessel-Like Microtunnels with Biomimetic Octopus Tentacles for Seizing and Detecting Exosomes to Diagnose Pancreatic Cancer.

Microchip-based exosome analysis has emerged as a promising approach for liquid biopsy in cancer diagnosis, treatment monitoring, and prognostic evalu...

May 27 2025 40424013
Diversity of U1 Small Nuclear RNAs and Diagnostic Methods for Their Mutations.

U1 small nuclear RNA (snRNA) mutations are recurrent non-coding alterations found in various malignancies, yet their identification has proven challen...

May 27 2025 40425278
China Protocol for early screening, precise diagnosis, and individualized treatment of lung cancer.

Early screening, diagnosis, and treatment of lung cancer are pivotal in clinical practice since the tumor stage remains the most dominant factor that ...

May 27 2025 40425545
PathoGraph: A Graph-Based Method for Standardized Representation of Pathology Knowledge.

Pathology data, primarily consisting of slides and diagnostic reports, inherently contain knowledge that is pivotal for advancing data-driven biomedic...

May 27 2025 40425649
Advancing breast, lung and prostate cancer research with federated learning. A systematic review.

Federated learning (FL) is advancing cancer research by enabling privacy-preserving collaborative training of machine learning (ML) models on diverse,...

May 27 2025 40425787
Interpretable niche-based cell‒cell communication inference using multi-view graph neural networks.

Cell‒cell communication (CCC) is a fundamental biological process for the harmonious functioning of biological systems. Increasing evidence indicates ...

May 27 2025 40425827
Radiomics applications in the modern management of esophageal squamous cell carcinoma.

Esophageal cancer ranks among the most lethal malignancies globally, with China accounting for more than half of worldwide esophageal squamous cell ca...

May 27 2025 40425893
Deep Learning Auto-segmentation of Diffuse Midline Glioma on Multimodal Magnetic Resonance Images.

Diffuse midline glioma (DMG) H3 K27M-altered is a rare pediatric brainstem cancer with poor prognosis. To advance the development of predictive models...

May 27 2025 40425959
Optimizing workflows for metastatic central nervous system disease: a systematic review and proposed guidelines.

INTRODUCTION: Brain and spine metastases are a major cause of morbidity and mortality in patients with malignancy. Aside from advancements in medical,...

May 27 2025 40426009
Improving Breast Cancer Diagnosis in Ultrasound Images Using Deep Learning with Feature Fusion and Attention Mechanism.

RATIONALE AND OBJECTIVES: Early detection of malignant lesions in ultrasound images is crucial for effective cancer diagnosis and treatment. While tra...

May 27 2025 40436710
Interpretable Machine Learning Models for Differentiating Glioblastoma From Solitary Brain Metastasis Using Radiomics.

PURPOSE: To develop and validate interpretable machine learning models for differentiating glioblastoma (GB) from solitary brain metastasis (SBM) usin...

May 27 2025 40436711
Artificial intelligence in breast pathology: Overview and recent updates.

Breast cancer remains a major global health concern where timely and accurate pathologic diagnosis is critical for effective management. The tradition...

May 27 2025 40441444
[Progress of individualized precision therapy for peritoneal metastasis in gastric cancer].

Peritoneal metastasis represents the most aggressive form of gastric cancer metastasis and serves as a primary contributor to poor prognosis. Conventi...

May 27 2025 40443328
[Current status and trends of perioperative immunotherapy for gastric cancer].

In recent years,immunotherapy,particularly immune checkpoint inhibitors,has been widely used in the treatment of both solid and non-solid tumors,and i...

May 27 2025 40443332
Multiple Instance Learning for the Detection of Lymph Node and Omental Metastases in Carcinoma of the Ovaries, Fallopian Tubes and Peritoneum.

: Surgical pathology of tubo-ovarian and peritoneal cancer carries a well-recognised diagnostic workload, partly due to the large amount of non-primar...

May 27 2025 40507270
Baseline Radiomics as a Prognostic Tool for Clinical Benefit from Immune Checkpoint Inhibition in Inoperable NSCLC Without Activating Mutations.

Checkpoint inhibitors (ICIs) are key therapies for NSCLC, but current selection criteria, such as excluding mutation carriers and assessing PD-L1, la...

May 27 2025 40507271
Identification of a novel chemotherapy benefit index for patients with advanced ovarian cancer based on Bayesian network analysis.

BACKGROUND: This study aims to evaluate the efficacy of chemotherapy and optimize treatment strategies for patients with advanced ovarian cancer.

May 27 2025 40424327
AI-based multimodal prediction of lymph node metastasis and capsular invasion in cT1N0M0 papillary thyroid carcinoma.

BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. A...

May 27 2025 40496555
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