Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Arginine methylation patterns in LUAD: defining prognostic subtypes and relevance to immunotherapy.

BACKGROUND: Lung cancer remains the leading cause of cancer-related death worldwide, with lung adenocarcinoma (LUAD) being the most common subtype. Arginine methylation, driven by protein arginine methyltransferases (PRMTs) has been connected to cancer biology, particularly in modulating cancer immunity. Thus, developing a PRMTs-related prognostic model might help create more personalized treatmen...

May 21 2025 40399547

Prediction of B/T Subtype and ETV6-RUNX1 Translocation in Pediatric Acute Lymphoblastic Leukemia by Deep Learning Analysis of Giemsa-Stained Whole Slide Images of Bone Marrow Aspirates.

BACKGROUND: Accurate determination of B/T-cell lineage and the presence of the ETV6-RUNX1 translocation is critical for diagnosing acute lymphoblastic leukemia (ALL), as these factors influence treatment decisions and outcomes. However, these diagnostic processes often rely on advanced tools unavailable in low-resource settings, creating a need for alternative solutions.

May 21 2025 40399768
Synthesizing [F]PSMA-1007 PET bone images from CT images with GAN for early detection of prostate cancer bone metastases: a pilot validation study.

BACKGROUND: [F]FDG PET/CT scan combined with [F]PSMA-1007 PET/CT scan is commonly conducted for detecting bone metastases in prostate cancer (PCa). Ho...

May 21 2025 40399853
Establishment of a prognostic model based on ER stress-related cell death genes and proposing a novel combination therapy in acute myeloid leukemia.

BACKGROUND: Acute myeloid leukemia (AML) is a highly heterogeneous malignancy, presenting significant challenges in accurately predicting patient prog...

May 21 2025 40399990
Deep learning Radiopathomics based on pretreatment MRI and whole slide images for predicting overall survival in locally advanced nasopharyngeal carcinoma.

PURPOSE: To develop an integrative radiopathomic model based on deep learning to predict overall survival (OS) in locally advanced nasopharyngeal carc...

May 21 2025 40409367
BrainView: A Cloud-based Deep Learning System for Brain Image Segmentation, Tumor Detection and Visualization.

A brain tumor is an abnormal growth in the brain that disrupts its functionality and poses a significant threat to human life by damaging neurons. Ear...

May 21 2025 40409506
The Desmoid Dilemma: Challenges and Opportunities in Assessing Tumor Burden and Therapeutic Response.

Desmoid tumors are rare, locally invasive soft-tissue tumors with unpredictable clinical behavior. Imaging plays a crucial role in their diagnosis, me...

May 21 2025 40422547
Radiomics and AI-Based Prediction of MGMT Methylation Status in Glioblastoma Using Multiparametric MRI: A Hybrid Feature Weighting Approach.

: Glioblastoma (GBM) is a highly aggressive primary central nervous system tumor with a median survival of 14 months. MGMT (O6-methylguanine-DNA methy...

May 21 2025 40428285
Towards automating risk stratification of intraductal papillary mucinous Neoplasms: Artificial intelligence advances beyond human expertise with confocal laser endomicroscopy.

BACKGROUND AND AIMS: Endoscopic Ultrasound (EUS)-guided needle-based confocal laser endomicroscopy (nCLE) enables real-time microscopic visualization ...

May 21 2025 40447463
ImmunoStruct: a multimodal neural network framework for immunogenicity prediction from peptide-MHC sequence, structure, and biochemical properties.

Epitope-based vaccines are promising therapeutic modalities for infectious diseases and cancer, but identifying immunogenic epitopes is challenging. T...

May 21 2025 40470208
Applications of machine learning for immunophenotypic measurable residual disease assessment in acute myeloid leukemia.

Immunophenotypic detection and quantification of residual leukemic cells by multiparameter flow cytometry is increasingly adopted in the clinical prac...

May 21 2025 40400510
Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy.

Oncolytic vaccinia viruses armed with interleukins represent a promising frontier in tumor therapy. Oncolytic vaccinia viruses express IL-2, IL-10, IL...

May 21 2025 40469178
Global research trends in bone tumors: a bibliometric analysis of medical imaging.

BACKGROUND: Bone tumors, due to their high rate of misdiagnosis, pose significant clinical challenges in diagnosis and treatment. Medical imaging play...

May 21 2025 40469196
Prognostic effect of CD74 and development of a radiomic model for predicting CD74 expression in non-small cell lung cancer.

BACKGROUND: The classical prognostic indicators of lung cancer are no longer sufficient for prognostic stratification and individualized treatment of ...

May 21 2025 40470045
Res-ECA-UNet++: an automatic segmentation model for ovarian tumor ultrasound images based on residual networks and channel attention mechanism.

OBJECTIVE: Ultrasound imaging has emerged as the preferred imaging modality for ovarian tumor screening due to its non-invasive nature and real-time d...

May 21 2025 40470046
Application of artificial intelligence in palliative care: a bibliometric analysis of research hotspots and trends.

BACKGROUND: Palliative care, essential for improving quality of life in patients with serious illnesses, faces challenges such as resource limitations...

May 21 2025 40470051
Imaging patterns and recommendations for diagnosis, staging, and management of lung cancer.

Lung cancer is the second most commonly diagnosed cancer worldwide. In the present era of targeted therapy for various lung cancer mutations, it is es...

May 21 2025 40486071
Microbial vitamin biosynthesis links gut microbiota dynamics to chemotherapy toxicity.

Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show that the gut microbiota influences and is influenced...

May 20 2025 40391895
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