Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 4901-4920 of 18,747 articles

Exploring Hidden Dangers: Predicting Mycotoxin-like Toxicity and Mapping Toxicological Networks in Hepatocellular Carcinoma.

Mycotoxins are potent triggers of hepatocellular carcinoma (HCC) due to their intricate interplay with cellular macromolecules and signaling pathways. This study integrates machine learning and biomolecular analyses to elucidate the mechanisms underlying mycotoxin-induced hepatocarcinogenesis. Using a data set of 1767 mycotoxins and 1706 non-mycotoxin fungal metabolites, we evaluated 51 machine le...

May 20 2025 40393043

Label-Free and Intelligent Cell Death Recognition Toward Lung Cancer Chemotherapy.

The lack of high-throughput, label-free, and intelligent recognition models for assessing cell death hinders the broad application of cell death analysis in chemotherapy for lung cancer. We propose an intelligent quantitative detection technique for cell deaths. Using high-throughput quantitative phase imaging flow cytometry to capture numerous label-free images and employing convolutional neural ...

May 20 2025 40391419
Transforming healthcare: the impact of artificial intelligence on diagnostics, pharmaceuticals and ethical considerations - a comprehensive review.

Interpretability of results remains challenging in most health industries since patients may suffer life-threatening consequences from an inaccurate d...

May 20 2025 40391953
Integrating machine learning and molecular docking to decipher the molecular network of aflatoxin b1-induced hepatocellular carcinoma.

OBJECTIVE: This study aims to investigate the molecular mechanisms underlying hepatocellular carcinoma (HCC) induced by Aflatoxin B1 (AFB1).

May 20 2025 40392001
Improving Ovarian Cancer Subtyping with Computer Vision Models on Tiled Histopathological Images.

Ovarian cancer remains one of the most challenging cancers to diagnose due to its non-specific symptoms, lack of reliable screening tests, and the com...

May 20 2025 40392413
A Novel Telomere Maintenance Gene-Related Model for Prognosis Prediction in Gastric Cancer.

Gastric cancer (GC) remains a significant clinical challenge due to its frequent late-stage diagnosis and limited treatment stratification. Telomere m...

May 20 2025 40392448
Deep learning predicts microsatellite instability status in colorectal carcinoma in an ethnically heterogeneous population in South Africa.

BACKGROUND: Deep learning (DL) models are effective pre-screening tools for detecting mismatch repair deficiency (dMMR) in colorectal carcinoma (CRC)....

May 20 2025 40393786
Deep learning-based interpretable prediction of recurrence of diffuse large B-cell lymphoma.

BACKGROUND: The heterogeneous and aggressive nature of diffuse large B-cell lymphoma (DLBCL) presents significant treatment challenges as up to 50% of...

May 20 2025 40394100
An artificial intelligence-based model for prediction of clonal hematopoiesis variants in cell-free DNA samples.

Circulating tumor DNA is a critical biomarker in cancer diagnostics, but its accurate interpretation requires careful consideration of clonal hematopo...

May 20 2025 40394286
Histopathology-Based Prostate Cancer Classification Using ResNet: A Comprehensive Deep Learning Analysis.

Prostate cancer is the most prevalent solid tumor in males and one of the most common causes of male mortality. It is the most common type of cancer i...

May 20 2025 40394318
A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathway.

Wnt signaling is important in embryonic development and tumorigenesis. These biological effects can be exerted by the activation of the β-catenin-depe...

May 20 2025 40394415
Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic study.

BACKGROUND: Pyroptosis is a form of programmed cell death characterized by inflammasome activation and the release of inflammatory cytokines, which in...

May 20 2025 40394449
Future of image enhanced endoscopy of esophageal adenocarcinoma.

Barrett's esophagus is a premalignant precursor lesion of esophageal adenocarcinoma that affects approximately 1% of the population worldwide. Esophag...

May 20 2025 40394929
Trading off Iodine and Radiation Dose in Coronary Computed Tomography.

Coronary CT angiography (CCTA) has seen steady progress since its inception, becoming a key player in the non-invasive assessment of coronary artery d...

May 20 2025 40422966
Segmentation of Non-Small Cell Lung Carcinomas: Introducing DRU-Net and Multi-Lens Distortion.

The increased workload in pathology laboratories today means automated tools such as artificial intelligence models can be useful, helping pathologist...

May 20 2025 40423022
New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma.

Hepatocellular carcinoma remains one of the leading contributors to global cancer mortality, frequently stemming from chronic liver conditions, such a...

May 20 2025 40427070
Predicting Treatment Outcomes in Glioblastoma: A Risk Score Model for TMZ Resistance and Immune Checkpoint Inhibition.

Glioblastoma (GBM) presents significant therapeutic challenges due to its invasive nature and resistance to standard chemotherapy, i.e., temozolomide ...

May 20 2025 40427760
Exploring the Role of Peritumoral Edema in Predicting Lung Cancer Subtypes Through T2-FLAIR Digital Subtraction Imaging of Metastatic Brain Tumors.

: This study aimed to investigate whether small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) can be distinguished based on radiomics...

May 20 2025 40428276
Exploring the Potential of Digital Twins in Cancer Treatment: A Narrative Review of Reviews.

Digital twin (DT) technology, integrated with artificial intelligence (AI) and machine learning (ML), holds significant potential to transform oncolo...

May 20 2025 40429568
Machine-learning-assisted universal protein activation in living mice.

A universal strategy to precisely control protein activation in living animals is crucial for gain-of-function study of proteins under in vivo setting...

May 20 2025 40436016
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