Oncology/Hematology

Machine learning-based identification of an immunotherapy-related signature to enhance outcomes and immunotherapy responses in melanoma.

BACKGROUND: Immunotherapy has revolutionized skin cutaneous melanoma treatment, but response variability due to tumor heterogeneity necessitates robust biomarkers for predicting immunotherapy response.

Intratumoral and Peritumoral Radiomics for Predicting the Prognosis of High-grade Serous Ovarian Cancer Patients Receiving Platinum-Based Chemotherapy.

RATIONALE AND OBJECTIVES: This study aimed to develop a deep learning (DL) prognostic model to evaluate the significance of intra- and peritumoral radiomics in predicting outcomes for high-grade serous ovarian cancer (HGSOC) patients receiving platinum-based chemotherapy.

Enhanced network synchronization connectivity following transcranial direct current stimulation (tDCS) in bipolar depression: Effects on EEG oscillations and deep learning-based predictors of clinical remission.

AIM: To investigate oscillatory networks in bipolar depression, effects of a home-based tDCS treatment protocol, and potential predictors of clinical ...

CBAM-RIUnet: Breast Tumor Segmentation With Enhanced Breast Ultrasound and Test-Time Augmentation.

This study addresses the challenge of precise breast tumor segmentation in ultrasound images, crucial for effective Computer-Aided Diagnosis (CAD) in ...

From whole-slide image to biomarker prediction: end-to-end weakly supervised deep learning in computational pathology.

Hematoxylin- and eosin-stained whole-slide images (WSIs) are the foundation of diagnosis of cancer. In recent years, development of deep learning-base...

Will Transformers change gastrointestinal endoscopic image analysis? A comparative analysis between CNNs and Transformers, in terms of performance, robustness and generalization.

Gastrointestinal endoscopic image analysis presents significant challenges, such as considerable variations in quality due to the challenging in-body ...

Deciphering the cytotoxicity of micro- and nanoplastics in Caco-2 cells through meta-analysis and machine learning.

Plastic pollution, driven by micro- and nanoplastics (MNPs), poses a major environmental threat, exposing humans through various routes. Despite human...

Use machine learning to predict pulmonary metastasis of esophageal cancer: a population-based study.

BACKGROUND: This study aims to establish a predictive model for assessing the risk of esophageal cancer lung metastasis using machine learning techniq...

Leveraging immuno-fluorescence data to reduce pathologist annotation requirements in lung tumor segmentation using deep learning.

The main bottleneck in training a robust tumor segmentation algorithm for non-small cell lung cancer (NSCLC) on H&E is generating sufficient ground tr...

Deep neural network models for cell type prediction based on single-cell Hi-C data.

BACKGROUND: Cell type prediction is crucial to cell type identification of genomics, cancer diagnosis and drug development, and it can solve the time-...

Machine learning-based evaluation of prognostic factors for mortality and relapse in patients with acute lymphoblastic leukemia: a comparative simulation study.

BACKGROUND: Predicting mortality and relapse in children with acute lymphoblastic leukemia (ALL) is crucial for effective treatment and follow-up mana...

RCC-Supporter: supporting renal cell carcinoma treatment decision-making using machine learning.

BACKGROUND: The population diagnosed with renal cell carcinoma, especially in Asia, represents 36.6% of global cases, with the incidence rate of renal...

An enhanced Garter Snake Optimization-assisted deep learning model for lung cancer segmentation and classification using CT images.

An early detection of lung tumors is critical for better treatment results, and CT scans can reveal lumps in the lungs which are too small to be picke...

Antiproliferative and Pro-apoptotic Activities of vent. Leaves on the Human Breast Adenocarcinoma Cell Line (MCF-7).

BACKGROUND: Breast cancer is the most common cancer among women worldwide, impacting not only the patients but also their families and communities. v...

Pulmonary nodule visualization and evaluation of AI-based detection at various ultra-low-dose levels using photon-counting detector CT.

BACKGROUND: Radiation dose should be as low as reasonably achievable. With the invention of photon-counting detector computed tomography (PCD-CT), the...

Development and validation of machine learning models for predicting cancer-related fatigue in lymphoma survivors.

BACKGROUND: New cases of lymphoma are rising, and the symptom burden, like cancer-related fatigue (CRF), severely impacts the quality of life of lymph...

Multitask machine learning-based tumor-associated collagen signatures predict peritoneal recurrence and disease-free survival in gastric cancer.

BACKGROUND: Accurate prediction of peritoneal recurrence for gastric cancer (GC) is crucial in clinic. The collagen alterations in tumor microenvironm...

Artificial Intelligence Algorithm Can Predict Lymph Node Malignancy from Endobronchial Ultrasound Transbronchial Needle Aspiration Images for Non-Small Cell Lung Cancer.

INTRODUCTION: Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) for lung cancer staging is operator dependent, resulting in high r...

Multimodal convolutional neural network-based algorithm for real-time detection and differentiation of malignant and inflammatory biliary strictures in cholangioscopy: a proof-of-concept study (with video).

BACKGROUND AND AIMS: Deep learning algorithms gained attention for detection (computer-aided detection [CADe]) of biliary tract cancer in digital sing...

Integrated machine learning algorithms identify KIF15 as a potential prognostic biomarker and correlated with stemness in triple-negative breast cancer.

Cancer stem cells (CSCs) have the potential to self-renew and induce cancer, which may contribute to a poor prognosis by enabling metastasis, recurren...