Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 12561-12580 of 19,032 articles

3D Deep Learning for Multi-modal Imaging-Guided Survival Time Prediction of Brain Tumor Patients.

High-grade glioma is the most aggressive and severe brain tumor that leads to death of almost 50% patients in 1-2 years. Thus, accurate prognosis for glioma patients would provide essential guidelines for their treatment planning. Conventional survival prediction generally utilizes clinical information and limited handcrafted features from magnetic resonance images (MRI), which is often time consu...

Oct 2 2016 28149967

MiRNATIP: a SOM-based miRNA-target interactions predictor.

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNA sequences with regulatory functions to post-transcriptional level for several biological processes, such as cell disease progression and metastasis. MiRNAs interact with target messenger RNA (mRNA) genes by base pairing. Experimental identification of miRNA target is one of the major challenges in cancer biology because miRNAs can act as tumo...

Sep 22 2016 28185545
Unsupervised detection of cancer driver mutations with parsimony-guided learning.

Methods are needed to reliably prioritize biologically active driver mutations over inactive passengers in high-throughput sequencing cancer data sets...

Sep 12 2016 27618449
When machine vision meets histology: A comparative evaluation of model architecture for classification of histology sections.

Classification of histology sections in large cohorts, in terms of distinct regions of microanatomy (e.g., stromal) and histopathology (e.g., tumor, n...

Sep 9 2016 27644083
Computer-assisted framework for machine-learning-based delineation of GTV regions on datasets of planning CT and PET/CT images.

We have proposed a computer-assisted framework for machine-learning-based delineation of gross tumor volumes (GTVs) following an optimum contour selec...

Sep 8 2016 27609193
Risk analysis of lung cancer and effects of stress level on cancer risk through neuro-fuzzy model.

A significant number of people pass away due to limited medical resources for the battle with cancer. Fatal cases can be reduced by using the computat...

Sep 5 2016 28110738
New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity.

Betulin and its semisynthetic derivatives exhibit a cytotoxic activity toward various cancer cell lines. These compounds are a promising and potentia...

Sep 1 2016 28111514
Predicting Outcomes of Hormone and Chemotherapy in the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) Study by Biochemically-inspired Machine Learning.

Genomic aberrations and gene expression-defined subtypes in the large METABRIC patient cohort have been used to stratify and predict survival. The pre...

Aug 31 2016 28620450
Robotic single site staging in endometrial cancer: A multi-institution study.

OBJECTIVE: To evaluate the feasibility and the safety of robotic single site hysterectomy (RSSH) plus or less pelvic lymphadenectomy in FIGO stage I-I...

Aug 30 2016 27612413
Bioactive properties and functional constituents of Hypericum androsaemum L.: A focus on the phenolic profile.

Hypericum androsaemum L. ethanol:water extract acted as a lipid peroxidation inhibitor and free radical scavenger. A marked inhibition of the growth o...

Aug 28 2016 28460934
A Mass Spectrometric Analysis Method Based on PPCA and SVM for Early Detection of Ovarian Cancer.

Background. Surfaced-enhanced laser desorption-ionization-time of flight mass spectrometry (SELDI-TOF-MS) technology plays an important role in the ea...

Aug 23 2016 27642365
Risk Assessment for Venous Thromboembolism in Chemotherapy-Treated Ambulatory Cancer Patients.

OBJECTIVE: To design a precision medicine approach aimed at exploiting significant patterns in data, in order to produce venous thromboembolism (VTE) ...

Aug 19 2016 27491558
Hypofractionated image guided radiation therapy followed by prostate seed implant boost for men with newly diagnosed intermediate and high risk adenocarcinoma of the prostate: Preliminary results of a phase 2 prospective study.

PURPOSE: A phase 2 protocol was designed and implemented to assess the toxicity and efficacy of hypofractionated image guided intensity modulated radi...

Aug 18 2016 28740903
Modeling the reflection of Photosynthetically active radiation in a monodominant floodable forest in the Pantanal of Mato Grosso State using multivariate statistics and neural networks.

The study of radiation entrance and exit dynamics and energy consumption in a system is important for understanding the environmental processes that r...

Aug 15 2016 27556220
Liver Tumor Segmentation from MR Images Using 3D Fast Marching Algorithm and Single Hidden Layer Feedforward Neural Network.

Objective. Our objective is to develop a computerized scheme for liver tumor segmentation in MR images. Materials and Methods. Our proposed scheme con...

Aug 14 2016 27597960
DMAK: A curated pan-cancer DNA methylation annotation knowledgebase.

Pan-cancer analysis can identify cell- and tissue-specific genomic loci and regions with underlying biological functions. Here we present an online cu...

Aug 12 2016 27645405
Cytotoxic and Antimicrobial Constituents from the Essential Oil of Lippia alba (Verbenaceae).

(Verbenaceae) is a plant widely used in folk medicine to treat various diseases. The present work deals with the chemical composition of the crude es...

Aug 12 2016 28930132
Multimodal US-gamma imaging using collaborative robotics for cancer staging biopsies.

PURPOSE: The staging of female breast cancer requires detailed information about the level of cancer spread through the lymphatic system. Common pract...

Aug 9 2016 27507282
Deep learning based classification of breast tumors with shear-wave elastography.

This study aims to build a deep learning (DL) architecture for automated extraction of learned-from-data image features from the shear-wave elastograp...

Aug 6 2016 27529139
Neuro-endocrine effects of aqueous extract of (Linn.) leaf in male Wistar rat model of cyclophosphamide-induced reproductive toxicity.

Cyclophosphamide (CP) is a widely used cytotoxic alkylating agent with antitumor and immunosuppressant properties that is associated with various form...

Aug 3 2016 28959584
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