Ophthalmology

Latest AI and machine learning research in ophthalmology for healthcare professionals.

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A Datasheet for Age-Related Eye Disease Study 2 on the Database of Genotypes and Phenotypes.

OBJECTIVE: To provide a comprehensive summary of the controlled-access Age-Related Eye Disease Study 2 (AREDS2) data elements, encompassing phenotypic, imaging, dietary, genetic, and ancillary data. DESIGN: Dataset description of a multicenter, phase III, randomized clinical trial evaluating lutein + zeaxanthin, ω-3, or both long-chain polyunsaturated fatty acid supplementation in intermediate age...

Oct 2 2025 41450867

Chemiluminescent biosensors for pharmaceutical analysis: innovations, challenges, and future prospects.

Chemiluminescent (CL) biosensors have rapidly emerged as indispensable analytical tools within the multifaceted domains of pharmaceutical research, development, and clinical diagnostics. This prominence stems from their intrinsic attributes such as higher sensitivity, low background noise, and inherent amenability to miniaturization for portable, real-time readout capabilities. This comprehensive ...

Oct 1 2025 41056881
Evaluating large language models in answering patient questions about eye removal surgeries.

PURPOSE: To evaluate the performance of ChatGPT-4 and Gemini, two large language models (LLMs), in addressing frequently asked questions (FAQs) about ...

Sep 30 2025 41026610
Spatial architecture of development and disease.

Tissue architecture is a product of a multilayered molecular landscape, where even subtle disruptions in the spatial context can initiate or reflect d...

Sep 30 2025 41028908
Integrated chemometric and machine learning approaches to study the properties of pure and adulterated edible oils.

The adulteration of pure edible oils, particularly with cost-effective oils like palm oil, has become a significant concern due to its detrimental imp...

Sep 29 2025 41046602
Tissue-Engineered Endothelial Keratoplasty with Controlled Cell Density: Toward Super TEEKs.

Over the past 20 years, endothelial keratoplasty procedures have revolutionized the treatment of corneal endothelial disorders. These conditions have ...

Sep 23 2025 40986463
Artificial intelligence-driven patient history and symptoms combined with slit-lamp eye simulation for enhancing the clinical training of students.

CLINICAL RELEVANCE: Communication between eye care practitioners is essential to optimise health care. Traditionally, actors have been used prior to r...

Sep 21 2025 40975895
Advancements in ocular blood flow imaging: Clinical applications of laser speckle flowgraphy and optical coherence tomography angiography in retinal and choroidal vascular diseases.

Ocular blood flow imaging techniques have become indispensable in current clinical practice because retinal vascular disturbances have been implicated...

Sep 21 2025 40987377
OcuViT: A Vision Transformer-Based Approach for Automated Diabetic Retinopathy and AMD Classification.

Early detection and accurate classification of retinal diseases, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD), are ess...

Sep 19 2025 40973913
Fluid/function correlation using AI-based quantification versus central subfield thickness in treatment-naïve and pre-treated patients with neovascular AMD in a real-world setting.

PURPOSE: To investigate the association between best-corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfie...

Sep 18 2025 40965041
Artificial intelligence in age-related macular degeneration: Advancing diagnosis, prognosis, and treatment.

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in older adults. While anti-vascular endothelial growth factor (...

Sep 18 2025 40975441
Global Trends and Emerging Themes in Tele-Ophthalmology Research: A Bibliometric Analysis (1993 to 2024).

BACKGROUND: Tele-ophthalmology is transforming eye care delivery, particularly in remote and underserved areas, where specialist shortages and geograp...

Sep 17 2025 40959961
Unfolding the diagnostic pipeline of diabetic retinopathy with artificial intelligence: A systematic review.

Diabetic retinopathy (DR) is a leading cause of vision impairment globally, necessitating early and accurate detection through effective screening met...

Sep 17 2025 40972797
Dysmorphic neurons express markers of inhibitory glycinergic signaling in focal cortical dysplasia IIb.

Focal cortical dysplasia (FCD) is a neurodevelopmental malformation that often manifests as medically refractory epilepsy. A key histological hallmark...

Sep 16 2025 40957662
Counterfactual causal inference for robust visual question answering.

Visual Question Answering (VQA) systems have seen remarkable progress with the incorporation of multimodal data. However, their performance is still h...

Sep 16 2025 40972116
Impact of artificial intelligence in vision science: A systematic review of progress, emerging trends, data domain quantification, and critical gaps.

The prominence of artificial intelligence (AI) is growing exponentially, yet its implementation across research domains is uneven. To quantify AI tren...

Sep 16 2025 40967511
Diagnostic accuracy in dry eye: Insights into clinical and artificial intelligence limitations: Limitations of diagnostic accuracy in dry eye.

PURPOSE: To evaluate the agreement and performance of four large language models (LLMs)-ChatGPT-3.5, ChatGPT-4.0, Leny-ai, and MediSearch-in diagnosin...

Sep 15 2025 40954005
DGSSA: Domain generalization with structural and stylistic augmentation for retinal vessel segmentation.

Retinal vascular morphology plays a crucial role in diagnosing diseases such as diabetes, glaucoma, and hypertension, making accurate segmentation of ...

Sep 13 2025 40966934
Ultralow-power consumption bimodal synaptic transistors for high-efficiency neuromorphic vision system.

Artificial vision synaptic devices, characterized by low power consumption and high parallelism efficiency, hold significant promise for artificial vi...

Sep 12 2025 40972300
Customizing AI-based screening with real-world data: Practical insights from diabetic retinopathy.

PURPOSE: Diabetic retinopathy (DR) is a leading cause of vision loss in middle-aged adults globally. Although artificial intelligence (AI)-based scree...

Sep 11 2025 40932047
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