Orthopedics

Artificial neural network simulation of lower limb joint angles in normal and impaired human gait.

PURPOSE: Simulating the complexities of lower limb motion can be useful for orthosis or rehabilitation planning. The aim of this study was to develop an artificial neural network (ANN) able to accurately simulate the changes in the angle of the ankle, knee and hip joints during the gait cycle, then to use it to simulate the impact of a restricted range of ankle and hip joint angle changes on the p...

In silico Prediction of Inhibitory Constant of Thrombin Inhibitors Using Machine Learning.

BACKGROUND: Thrombin is the central protease of the vertebrate blood coagulation cascade, which is closely related to cardiovascular diseases. The inhibitory constant Ki is the most significant property of thrombin inhibitors.

Altered Expression Patterns of the Sumoylation Enzymes E1, E2 and E3 Are Associated with Glucose Oxidase- and UVA-Induced Cataractogenesis.

PURPOSE: Protein sumoylation is a well established regulatory mechanism that regulates chromatin structure and dynamics, cell proliferation and differ...

Comparison of Two Different Volumes of Ropivacaine Used in Nerve Stimulator Guided Inter-scalene Block for Arthroscopic Shoulder Surgery - A Randomized Controlled Trial.

BACKGROUND: This study was conducted to compare the analgesic efficacy of 10 ml versus 20 mL of 0.5% ropivacaine in nerve stimulator guided interscale...

Comparison between Colloid Preload and Coload in Bone Cement Implantation Syndrome under Spinal Anesthesia: A Randomized Controlled Trial.

BACKGROUND: Bone cement implantation syndrome (BCIS) is characterized by hypoxia hypotension cardiac arrest. There is not any research that investigat...

Th1/Th17 Cytokine Profile is Induced by Macrophage Migration Inhibitory Factor in Peripheral Blood Mononuclear Cells from Rheumatoid Arthritis Patients.

BACKGROUND: Macrophage migration inhibitory factor (MIF) is an immunoregulatory cytokine that plays a crucial role as a regulator of the innate and ad...

A Histological Study of Vasoconstriction by Local Anesthetics in Mandible.

To assess the effect of epinephrine-containing local anesthetics on vasoconstriction, we immunohistochemically measured the intravascular lumen area i...

Circulating Monocyte Chemoattractant Protein-1 Levels and Lumbar Bone Mineral Density in Korean Women.

BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is expressed in adipose tissue, macrophages, endothelial cells, and osteoblasts by parathyroid ...

[Effects of non-muscle myosin ⅡA silenced bone marrow mesenchymal stem cells on lung damage of rats at early stage of smoke inhalation injury].

To investigate the effects of non-muscle myosin ⅡA (NMⅡA) silenced bone marrow mesenchymal stem cells (BMSCs) on the lung damage of rats at early sta...

[Effectiveness of improved elbow anteromedial approach in treatment of ulna coronoid process fracture].

OBJECTIVE: To observe the effectiveness of reduction and fixation by the improved elbow anteromedial approach in treatment of ulna coronoid process fr...

[Improved technique for perforation of patella combined with suture anchor and non-tourniquet for repairing acute rupture of the bone tendon junction of quadriceps tendon].

OBJECTIVE: To investigate effectiveness of a improved technique for perforation of patella combined with suture anchor and non-tourniquet for repairin...

[Intramedullary nail combined with auxiliary plate and bone cement in treatment of pathologic fracture of extremities caused by metastatic tumors].

OBJECTIVE: To explore the application of intramedullary nail fixation combined with auxiliary plate and bone cement in the palliative treatment of pat...

[Preliminary effectiveness of laminated bevel suturing technique for treating acute closed Achilles tendon rupture].

OBJECTIVE: To introduce a modified technique for treating acute closed Achilles tendon rupture and evaluate the preliminary effectiveness.

Will intelligent machine learning revolutionize orthopedic imaging?

Effects of Single Vitamin D₃ Injection (200,000 Units) on Serum Fibroblast Growth Factor 23 and Sclerostin Levels in Subjects with Vitamin D Deficiency.

BACKGROUND: Vitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-...

Does a simple syringe applicator enhance bone cement set up time in knee arthroplasty?

BACKGROUND: The time required for polymethylmethacrylate (PMMA) cement curing or hardening can be modified by a number of variables including the mixi...

Incorporation of Anterior Lumbosacral Spine Exposure into a General Surgical Practice.

Many spine surgeons enlist the aid of an "access surgeon" to provide anterior exposure of the lumbosacral spine. We proposed that a single, community ...

Syphilis of the lumbar spine: A case report and review of the literature.

RATIONALE: Tertiary syphilis can manifest as gummatous disease, but gumma of the spine has been extremely rarely reported.

Percutaneous kyphoplasty versus posterior spinal fixation with vertebroplasty for treatment of Kümmell disease: A case-control study with minimal 2-year follow-up.

This is a retrospective case-control study.The aim of this study was to compare the surgical results of percutaneous kyphoplasty (KP) and posterior sp...

[Clinical research on perioperative restrictive fluid therapy combined with preoperative urination training in total hip arthroplasty].

OBJECTIVE: To evaluate the effectiveness and safety of restrictive fluid therapy combined with preoperative urination training during perioperative pe...