Orthopedics

Latest AI and machine learning research in orthopedics for healthcare professionals.

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Showing 61-80 of 8,094 articles

Improvement of Clinical Practice Guideline Appraisal by Human Experts and AI Agents by Using Structured Guidance: Systematic Review, Meta-Analysis, and Validation Study.

BACKGROUND: Rehabilitation clinical practice guidelines (CPGs) have increased rapidly, but inconsistent methodological quality limits their implementation. Although Appraisal of Guidelines for Research and Evaluation II (AGREE II) and Reporting Items for Practice Guidelines in Health Care (RIGHT) provide standardized appraisal frameworks, their application is time-consuming. Large language model (...

Aug 26 2026 42647856

Investigation of drilling and necrosis zone performance of split point drills in surgical cortical bone drilling.

The surgical bone drilling process is unavoidable in orthopedic, traumatological and dental applications for screw, plate and implant placement procedures. The mechanical and thermal effects generated during this process have a direct impact on both surgical success and post-operative recovery. The high axial forces, torque, and local temperature increases that occur during drilling can lead to se...

Aug 26 2026 42648309
Automated AI quantification of retinal parameters associated with axial length progression in children: a cohort study.

PURPOSE: This study investigated whether quantitative retinal parameters derived from colour fundus photography are associated with axial length (AL) ...

Aug 26 2026 42648888
Intratumoral Heterogeneity-aware Imaging Biomarkers for Bone Metastasis Risk Stratification in Breast Cancer.

RATIONALE AND OBJECTIVES: Breast cancer carries a substantial long-term risk of bone metastasis, which marks progression to incurable disease and seve...

Aug 26 2026 42648923
Adaptive Feature Selection for Hybrid EfficientNet-Residual Learning with Margin-Based Classification for Bone Fracture Detection (AFS-HERMS).

Automated bone-fracture detection from radiographic images remains a challenging task due to variations in anatomical structures, imaging conditions, ...

Aug 26 2026 42649340
Two-dimensional to three-dimensional knee reconstruction from radiographs and fluoroscopy: A systematic review of methods and accuracy (1995-2025).

Three-dimensional reconstruction of the knee plays an important role in orthopedic surgery and clinical decision-making, enabling precise implant plan...

Aug 26 2026 42647527
Deep learning differentiates myeloproliferative neoplasms and predicts JAK2 and CALR mutations from bone marrow smears.

Accurate differentiation of BCR::ABL1-negative myeloproliferative neoplasms (MPNs) based on bone marrow smear morphology remains challenging. While pr...

Aug 25 2026 42645155
Association between low skeletal muscle mass assessed by deep learning-based CT and MASLD: a prospective cohort study.

BACKGROUND: To explore the role of abdominal skeletal muscle mass in metabolic dysfunction-associated steatotic liver disease (MASLD) incidence and re...

Aug 25 2026 42649512
[Advances in deep learning multimodal fusion for early diagnosis of knee osteoarthritis].

Knee osteoarthritis (KOA) is a common chronic degenerative disease that causes pain, functional limitation, and reduced quality of life in middle-aged...

Aug 25 2026 42656119
Automated Hand Flexor Tendon Thickness Measurement in Systemic Sclerosis.

OBJECTIVE: Systemic sclerosis (SSc) can affect flexor tendons, contributing to hand function problems and reduced quality of life. Tendon changes are ...

Aug 25 2026 42640177
Bioinformatic identification of THY1 as a target in osteoarthritis and its effects on chondrocyte senescence and apoptosis.

Osteoarthritis (OA) is the most prevalent degenerative joint disease worldwide and imposes a substantial public health burden due to the lack of effec...

Aug 25 2026 42640506
Radiolabeled drug-delivery and controlled-release nanocarriers for arthritis: Clinical evidence, kinetic modeling, radiation-safety challenges, and precision nanotheranostics.

BACKGROUND: Arthritis comprises a heterogeneous group of inflammatory and degenerative joint disorders characterized by distinct pathological mechanis...

Aug 25 2026 42641260
Preventing fragility fractures: AI-based opportunistic osteoporosis detection in routine CT ​.

UNLABELLED: This study shows that an artificial intelligence tool can identify patterns of reduced bone mineral density in routine CT scans that would...

Aug 24 2026 42635729
Beyond robotics: a systematic review of technology integration in direct anterior approach total hip arthroplasty.

Technology-assisted implant positioning has emerged as a strategy to improve component placement accuracy in total hip arthroplasty (THA). However, th...

Aug 24 2026 42634058
Identification of a novel small-molecule modulator targeting SNX10 to inhibit osteoclastic bone resorption.

Current antiresorptive therapies reduce bone loss by eliminating osteoclasts or inhibiting their formation. However, these approaches could disrupt os...

Aug 23 2026 42633585
Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1-CD44 degenerative axis and therapeutic targets in IVDD.

BACKGROUND: Intervertebral disc degeneration (IVDD) is a common cause of chronic low back pain, imposing a significant economic and physiological burd...

Aug 22 2026 42668501
Apigenin Alleviates Ligamentum Flavum Ossification by Dual-Targeting CA9 and CDK6 and Modulating Calcium/PI3K-Akt Signaling.

While apigenin shows therapeutic potential for bone-related disorders like osteoporosis and osteoarthritis, its mechanisms in regulating ligamentum fl...

Aug 22 2026 42631587
Osteosarcopenia Revisited: From Mechanisms to Management.

Sarcopenia and osteoporosis are characterized by insufficient mass and function of skeletal muscle and bone, and often co-occur in older persons, a co...

Aug 22 2026 42631701
Robotic-referenced automated measurement of acetabular cup orientation on postoperative CT: development and internal validation.

Accurate measurement of acetabular cup orientation after total hip arthroplasty is essential, but postoperative CT relies on subjective, error-prone m...

Aug 22 2026 42631886
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