Orthopedics

Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection.

Supracondylar humerus fractures in children are among the most common elbow fractures in pediatrics. However, their diagnosis can be particularly challenging due to the anatomical characteristics and imaging features of the pediatric skeleton. In recent years, convolutional neural networks (CNNs) have achieved notable success in medical image analysis, though their performance typically relies on ...

Arylacetamides exhibit antiproliferative effects on non-transformed mammalian and vegetal cells and toxicity on crustaceans and fish embryos.

Non-clinical steps for development, validation and biosafety of new medicines and products comprises studies on cells, proteins, and animals. Herein, we evaluated the toxic activity of antitumoral 2-chloro--arylacetamides on eukaryotic dividing cells and animal replacement models. Firstly, the cytotoxicity of chloro (compound ), bromo (compound ) and nitro (compound ) acetamides was analyzed by fl...

Synovial fluid alpha-2-macroglobulin, gelsolin and lubricin distinguish between osteoarthritic and healthy equine joints.

BACKGROUND: Synovial fluid (SF) is an ideal sentinel fluid for osteoarthritis (OA) diagnosis and prognostication due to its critical homeostatic role,...

Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis.

AIM: This study aimed to investigate the effects of açai on bone and systemic damage caused by apical periodontitis (AP) in an animal model.

Challenges and Future Directions in Machine Learning for Osteoarthritis Prediction - Reply to the comments by Professor Takefuji.

Advances in Toughening Modification Methods for Epoxy Resins: A Comprehensive Review.

This work provides a comprehensive review of the recent advancements in the toughening modification methods for epoxy resins. The study explores a var...

Branding a New Technological Outlook for Future Orthopaedics.

Orthopedics is undergoing a transformative shift driven by personalized medical technologies that enhance precision, efficiency, and patient outcomes....

Serum Interleukin-6 Exhibits Better Diagnostic Performance Than Serum C-Reactive Protein in Acute Periprosthetic Joint Infection.

BACKGROUND: Inflammatory biomarkers serve as the first-line screening tools for diagnosing periprosthetic joint infection (PJI). However, the kinetics...

Performance of AI-Chatbots to Common Temporomandibular Joint Disorders (TMDs) Patient Queries: Accuracy, Completeness, Reliability and Readability.

TMDs are a common group of conditions affecting the temporomandibular joint (TMJ) often resulting from factors like injury, stress or teeth grinding. ...

Exploring the evolutionary adaptations of the unique seahorse tail's muscle architecture through modelling and robotic prototyping.

Seahorses possess a unique tail muscle architecture that enables efficient grasping and anchoring onto objects. This prehensile ability is crucial for...

OA-HybridCNN (OHC): An advanced deep learning fusion model for enhanced diagnostic accuracy in knee osteoarthritis imaging.

Knee osteoarthritis (KOA) is a leading cause of disability globally. Early and accurate diagnosis is paramount in preventing its progression and impro...

Impact of Vitamin D Deficiency on Short- and Long-Term Mortality in Patients Receiving Hip Fracture Surgery Under General Anesthesia: A Matched Cohort Study.

BACKGROUND: Although vitamin D deficiency (VDD) is common in patients who have hip fractures, the relationship between VDD and mortality risk remains ...

PEARL: Cascaded Self-Supervised Cross-Fusion Learning for Parallel MRI Acceleration.

Supervised deep learning (SDL) methodology holds promise for accelerated magnetic resonance imaging (AMRI) but is hampered by the reliance on extensiv...

The Role of Computed Tomography and Artificial Intelligence in Evaluating the Comorbidities of Chronic Obstructive Pulmonary Disease: A One-Stop CT Scanning for Lung Cancer Screening.

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly ...

Predictive value of the 5-item modified frailty index in adverse outcomes in total elbow arthroplasty: A machine-learning model analysis.

INTRODUCTION: The modified frailty index (mFI-5) is a five factor risk stratification tool predicated on functional status and key medical comorbiditi...

External Validation of a Novel Landmark-Based Deep Learning Automated Tibial Slope Measurement Algorithm Applied on Short Radiographs Obtained in Patients With ACL Injuries.

BACKGROUND: Deep learning algorithms can aid medical decision-making by performing routine tasks without any human error. Reading of standardized radi...

Development and Validation of the Novel Exergame-Integrated Robotic Stepper Device for Seated Lower Limb Rehabilitation.

Seated rehabilitation is essential in early-stage recovery for patients who can sit but cannot stand or walk. Robotic-based lower limb rehabilitation ...

Accelerated ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging of macromolecular fraction (MMF) in cortical bone based on a self-attention convolutional neural network.

PURPOSE: To combine ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging with a self-attention convolutional neural network (SAT...

Predicting the Risk of Lumbar Prolapsed Disc: A Gene Signature-Based Machine Learning Analysis.

INTRODUCTION: Lumbar prolapsed disc (LPD) is a leading cause of low back pain, contributing significantly to global disability and healthcare burden. ...

Towards optimized donor site closure of radial forearm flaps: A cohort study of two techniques.

The radial forearm flap (RFF) is widely used for microvascular reconstruction in the head and neck region, but donor site complications, such as flexo...