Orthopedics

Latest AI and machine learning research in orthopedics for healthcare professionals.

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Showing 1921-1940 of 8,094 articles

The role of lubrication in function and degeneration of articular cartilage: A critical review and perspectives.

Articular cartilage is a porous, soft tissue present in the synovial joints that distributes the load and lubricate the joint for smooth body movements. Arthritis or joint diseases lead to cartilage degeneration. However, the triggering factors of these joint diseases are still strongly debated, with uncertainties about the key mechanisms and the mechanochemical and biological interactions that ma...

Jun 25 2025 40562049

The role of generative artificial intelligence in deciding fusion treatment of lumbar degeneration: a comparative analysis and narrative review.

PURPOSE: This study analyzed responses and readability of generative artificial intelligence (AI) models to questions and recommendations from the 2014 Journal of Neurosurgery: Spine (JNS) guidelines for fusion procedures in the treatment of degenerative lumbar spine disease.

Jun 25 2025 40562990
In silico & in vitro approaches suggest osteoclastogenesis induction underlying fractures in Entrectinib-treated children.

Entrectinib, a potent, CNS-active, TRK and ROS1 inhibitor is associated with occurrence of bone fractures, particularly in pediatric patients. We emba...

Jun 25 2025 40563023
Fully automated workflow for designing patient-specific orthopaedic implants: Application to total knee arthroplasty.

Background Osteoarthritis affects about 528 million people worldwide, causing pain and stiffness in the joints. Arthroplasty is commonly performed to ...

Jun 25 2025 40561157
Individual muscle strengths in rehabilitation outcomes of distal radius fracture.

BACKGROUND: Distal radius fractures (DRFs) are common fracture types and elderly patients often struggle to achieve functional recovery, which could b...

Jun 24 2025 40551194
Neural network-based multi-task learning to assist planning of posterior spinal fusion surgery for adolescent idiopathic scoliosis.

PURPOSE: Posterior spinal instrumentation and fusion (PSF) is the gold standard for severe adolescent idiopathic scoliosis (AIS), yet instrumentation ...

Jun 24 2025 40553418
Artificial intelligence for predicting the risk of bone fragility fractures in osteoporosis.

Osteoporosis is widespread with a high incidence rate, resulting in fragility fractures which are a major contributor to mortality among the elderly. ...

Jun 24 2025 40555880
Diagnostic Performance of ChatGPT-4o in Detecting Hip Fractures on Pelvic X-rays.

INTRODUCTION: Hip fractures are a major orthopedic problem, especially in the elderly population. Hip fractures are usually diagnosed by clinical eval...

Jun 24 2025 40557058
Enabling Early Identification of Malignant Vertebral Compression Fractures via 2.5D Convolutional Neural Network Model with CT Image Analysis.

STUDY DESIGN: This study employed a retrospective data analysis approach combined with model development and validation.

Jun 23 2025 40548499
Prediction of Medial Tibiofemoral Joint Reaction Force Using Custom Instrumented Insoles and Neural Networks for Walking and Running Tasks.

Medial tibiofemoral joint reaction force is a clinically relevant variable for knee osteoarthritis progression and can be estimated using complex musc...

Jun 23 2025 40550501
Towards a comprehensive characterization of arteries and veins in retinal imaging.

Retinal fundus imaging is crucial for diagnosing and monitoring eye diseases, which are often linked to systemic health conditions such as diabetes an...

Jun 23 2025 40554981
MRI Radiomics and Automated Habitat Analysis Enhance Machine Learning Prediction of Bone Metastasis and High-Grade Gleason Scores in Prostate Cancer.

RATIONALE AND OBJECTIVES: To explore the value of machine learning models based on MRI radiomics and automated habitat analysis in predicting bone met...

Jun 23 2025 40555637
Axial Skeletal Assessment in Osteoporosis Using Radiofrequency Echographic Multi-spectrometry: Diagnostic Performance, Clinical Utility, and Future Directions.

Osteoporosis, a prevalent skeletal disorder, necessitates accurate and accessible diagnostic tools for effective disease management and fracture preve...

Jun 23 2025 40557059
Generalizable model to predict new or progressing compression fractures in tumor-infiltrated thoracolumbar vertebrae in an all-comer population.

OBJECTIVE: Neurosurgical evaluation is required in the setting of spinal metastases at high risk for leading to a vertebral body fracture. Both irradi...

Jun 20 2025 40540805
BoneDat, a database of standardized bone morphology for in silico analyses.

In silico analysis is key to understanding bone structure-function relationships in orthopedics and evolutionary biology, but its potential is limited...

Jun 20 2025 40541988
Adolescent lumbar disc herniation: etiology, diagnosis, and treatment options.

Adolescent lumbar disc herniation (ALDH) is a type of disease with a much lower incidence than adult lumbar disc herniation (LDH), which has a trend o...

Jun 20 2025 40542380
Identifying kinematic biomarkers of the dystrophic phenotype in a zebrafish model of Duchenne muscular dystrophy.

BACKGROUND: Dystrophin-deficient zebrafish larvae are a small, genetically tractable vertebrate model of Duchenne muscular dystrophy that is well suit...

Jun 20 2025 40542412
Bridging Health Literacy Gaps in Spine Care: Using ChatGPT-4o to Improve Patient-Education Materials.

BACKGROUND: Patient-education materials (PEMs) are essential to improve health literacy, engagement, and treatment adherence, yet many exceed the reco...

Jun 19 2025 40536932
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