Endocrinology

Osteoporosis

Latest AI and machine learning research in osteoporosis for healthcare professionals.

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Automated generation of personalized trajectories of aging phenotypes with DyViA-GAN

With a general increase in human lifespan, the need for technological advances to develop strategies...

Axon termination of the SAB motor neurons in C. elegans depends on pre- and postsynaptic activity

Axon termination is a critical step in neural circuit formation, but the contribution of activity fr...

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

All cells in an animal collectively ensure, moment-to-moment, the survival of the whole organism in ...

Motor cortex somatostatin interneurons adaptively shape the structure of action sequences

The brain can flexibly reorganize the structure of action sequence, or motor programs, to efficientl...

Nematic cell alignment directs calcium waves

Tissues rely on supracellular signals to coordinate their cells over a long range. Two such tissue-s...

Ventral striatal astrocytes contribute to reinforcement learning

Astrocytes influence synaptic plasticity and neuronal function through astrocytic calcium dynamics (...

Mechanical stretch disrupts calcium dynamics and redistributes Piezo1 in human astrocytes

Astrocytes regulate the activity of nearby neurons so disruption of astrocyte calcium dynamics by tr...

Predicting Future Development of Stress-Induced Anhedonia From Cortical Dynamics and Facial Expression

The current state of mental health treatment for individuals diagnosed with major depressive disorde...

Development and characterization of a scalable calcium imaging assay using human iPSC-derived neurons

Neuroscience drug discovery is challenged by the brain’s structural and cell-type complexity, which ...

The expression level of CACNA1C-encoded CaV1.2 is a tipping point between promotion and inhibition of dendritic growth in neurons

The CACNA1C gene encodes the CaV1.2 L-type voltage-gated calcium channel, which plays a crucial role...

Spine age estimation using deep learning in lateral spine radiographs and DXA VFA to predict incident fracture and mortality

Spine age estimated from lateral spine radiographs and DXA vertebral fracture assessments (VFAs) cou...

Deep Learning Study of Alkaptonuria Spinal Disease Assesses Global and Regional Severity and Detects Occult Treatment Status

Deep learning (DL) is increasingly used to analyze medical imaging, but is less refined for rare con...

The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood

The polygenic risk score genetic quantitative ultrasound speed of sound (gSOS) was developed using m...

Deep Learning on Histopathological Images to Predict Breast Cancer Recurrence Risk and Chemotherapy Benefit

Genomic testing has transformed treatment decisions for hormone receptor-positive, HER2-negative (HR...

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