Latest AI and machine learning research in other cancers for healthcare professionals.
BACKGROUND: Outcome prediction after Gamma Knife radiosurgery (GKRS) for pituitary adenomas remains guided by tumor anatomy, functional status, prior treatment, optic-apparatus proximity, and physician experience rather than individualized estimates of tumor response, biochemical remission, and endocrine morbidity. We developed THINKERS-PA, a mixture-of-experts (MoE) framework for outcome predicti...
The role of liver biopsy in hepatocellular carcinoma (HCC) is being re-evaluated in the era of precision oncology and biomarker-driven systemic therapy. Although histopathological examination remains the diagnostic gold standard, HCC is unique among solid tumors in that accurate non-invasive imaging criteria allow diagnosis without routine biopsy in selected clinical settings. However, increasing ...
Lesions with a Prostate Imaging-Reporting and Data System (PI-RADS) score of 4 or greater on multiparametric MRI (mpMRI) indicate a high likelihood of...
Breast cancer is a highly heterogeneous malignant tumour, whose initiation and progression are closely associated with aberrant rewiring of protein-pr...
BACKGROUND: Brain metastases from gastrointestinal (GI) malignancies are heterogeneous, while stereotactic radiosurgery dose selection remains guided ...
Pituitary neuroendocrine tumors (PitNETs) are common intracranial neoplasms with heterogeneous hormonal activity, invasiveness, and treatment response...
IMPORTANCE: Early liver metastasis (early-LiM) after pancreatectomy represents an aggressive biological phenotype of pancreatic ductal adenocarcinoma ...
IMPORTANCE: Pleomorphic dermal sarcomas (PDSs) are classified as sarcomas; however, they share features with cutaneous carcinomas, such as presentatio...
Prostate MRI has become integral to prostate cancer diagnosis and management, extending beyond prebiopsy triage to biopsy guidance, local staging, act...
Threats of workforce displacement and ethical uncertainty accompany the use of artificial intelligence in palliative care and nursing in general. Dimi...
Cancer remains one of the leading global health burdens, with increasing complexity in genomic, imaging, and clinical datasets presenting significant ...
Feline McDonough sarcoma (FMS)-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutations are clinically important in acute myeloid leuka...
BACKGROUND: Major depressive disorder exists along a continuum, from health through remission to active depression. Differentiating these states remai...
Gastrointestinal (GI) cancers, including colorectal, gastric, pancreatic, hepatocellular, and esophageal malignancies, remain a leading cause of cance...
DNA methylation alterations are early and stable hallmarks of cancer and represent promising biomarkers for non-invasive detection using circulating c...
Tertiary lymphoid structures（TLSs）are acpuired lymphoid aggregates in non-lymphoid tissues and play a significant role in the evolution, treatment, an...
OBJECTIVE: Intratumoral heterogeneity may limit the representativeness of biopsy-based Ki-67 assessment in breast cancer. We therefore developed and v...
Artificial Intelligence (AI) has become a fundamental driver of scientific progress, particularly in disease diagnosis, drug development, and drug del...
Cancer cells exhibit metabolic reprogramming, most notably the Warburg effect, which underscores their heightened dependency on glucose uptake facilit...
Bruton's Tyrosine Kinase (BTK) has been recently recognized as an important drug design target for treating B-cell malignancies. Unfortunately, drug r...