Pain Management

Latest AI and machine learning research in pain management for healthcare professionals.

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Architectural Safety Mechanisms for Multi-Agent Clinical LLM Systems Under Knowledge Base Distribution Shift

Objective: To evaluate whether multi-agent LLM architectures with explicit safety verification maintain guideline compliance when their clinical knowledge bases undergo temporal or institutional distribution shift. Materials and Methods: We designed a controlled evaluation framework using 50,000 synthetic type 2 diabetes patients with CKD and hypertension comorbidities (500 per experimental condit...

DeepVoyager-VL: Incentivizing Vision-in-the-Loop Search for Long-Horizon Multimodal Agents

Multimodal large language models (MLLMs) have advanced visual understanding and reasoning, yet their static parametric knowledge limits their ability to address knowledge-intensive and dynamically evolving open-world problems. To move beyond this limitation, multimodal deep search has emerged as a key direction for open-world information access, evolving from single-turn factual retrieval toward l...

Aug 3 2026 2608.01827v1
SWINSleepNet: A Hierarchical Context-Aware Framework for Sleep Staging (v2)

Automatic sleep staging is a critical role in sleep disorder diagnosis, sleep quality assessment, and long-term health monitoring; however, existing a...

Aug 3 2026 2608.02183v1
ReMiX-MAE: Learning Missing-Channel Cross-Modal Representations from RGB-Only Clinical Facial Videos for Sympathetic-Mediated Pain Assessment

Automated pain assessment in real clinics is limited by scarce clinically grounded facial video data with weak labels (often sequence-level self-repor...

Aug 3 2026 2608.02561v1
Remember-R1: Mitigating Long-Context Visual Forgetting through Reinforcement Learning

Multimodal large language models (MLLMs) increasingly rely on long chain-of-thought reasoning for complex tasks. However, as reasoning sequences lengt...

Aug 2 2026 2608.01314v1
Localising the epileptogenic zone from single-pulse electrical stimulation responses using cross-trial attention

Background: Analysis of SPES responses often relies on averaging repeated stimulation trials to improve signal quality. However, this may obscure clin...

See2Think: Do Multimodal Models Really Use Intermediate Visual States?

Multimodal large language models increasingly use sketches, annotations, tools, and intermediate images during reasoning, but it remains unclear wheth...

Jul 29 2026 2607.26769v1
Bayesian Feature Extraction using Gaussian and Diffused-gamma Priors for High Dimensional Spatio-Temporal Data

High-dimensional data with sparse structure and spatio-temporal dependence arise in many scientific domains. We develop a Bayesian feature-extraction ...

Jul 27 2026 2607.24378v1
JarvisHub: An Open Harness for Canvas-Native Multimodal Creative Agents

Creative AI is moving from single-step asset generation toward long-horizon multimodal production. Although recent generative models can synthesize hi...

Jul 26 2026 2607.23588v1
Assessing Pain Catastrophizing Through Free-Text Responses: A Validation of Large Language Models

Validated measures of pain catastrophizing primarily assess catastrophizing as a stable trait. However, emerging evidence suggests catastrophizing flu...

GEM-GPT Enables Personalized Cell Type-Resolved Therapeutic Design for Systems Pharmacology

Generative artificial intelligence (AI) has emerged as a powerful framework for drug discovery, yet most current approaches follow one-drug-one-gene t...

A Unified Tokenization Framework for Pain Recognition using Heterogeneous 3D Modalities

Pain is a complex and pervasive phenomenon affecting a large percentage of the population, and accurate assessment is essential for effective clinical...

Jul 22 2026 2607.19716v1
An Exploratory Analysis of Pain Localization via Explainable Computational Modeling

Automatic pain localization, which involves identifying the anatomical origin of pain from peripheral physiological signals without patient self-repor...

Jul 22 2026 2607.19726v1
Forecasting the Number of Harvest-ready Fruits of Sweet Peppers Using Multimodal Time-Series Data

Accurate yield forecasting at the individual-plant level is critical for precision agriculture and supply-chain planning, yet public datasets capturin...

Jul 22 2026 2607.19975v1
From CHESS to CHECKMATE: A Practical Score for Predicting Shunt Dependency Following Subarachnoid Hemorrhage

Objective: Shunt-dependent hydrocephalus is a common and costly complication of aneurysmal subarachnoid hemorrhage (aSAH), affecting up to 28% of surv...

Multi-model Segmentation and Morphometric Quantification of Cerebral Amyloid Angiopathy in Alzheimer's Disease Whole Slide Histopathology Images

Introduction: Cerebral amyloid angiopathy (CAA) is characterized by amyloid-beta deposition in cortical and leptomeningeal vessels and associated with...

CasanovoGUI: a cross-platform desktop application for deep learning-based de novo peptide sequencing with Casanovo

De novo peptide sequencing detects peptides directly from tandem mass spectra without a protein sequence database, and deep learning has substantially...

Accuracy Without Grounding: Diagnosing Visual Dependency Dissociation in Video LLM Benchmarks

Benchmark accuracy in video large language models (LLMs) is often treated as evidence of visual understanding. We audit this assumption across twenty ...

Jul 14 2026 2607.13305v1
Reducing information dependency does not cause training data privacy. Adversarially non-robust features do

In this paper, we challenge the prevailing view that information dependency (including rote memorization) drives training data exposure to image recon...

Jul 14 2026 2607.12354v1
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