Pain Management

[Early Systemic Administration of IL-10 Inhibits Neuropathic Pain in Adult Rats with Tibial Nerve Injury].

OBJECTIVES: To determine the effect of early systemic administration of IL-10 on peripheral neuropathic pain induced by tibial nerve permanent transection [modified spared nerve injury (mSNI)]in adult rats.

Multivariate classification of pain-evoked brain activity in temporomandibular disorder.

Central nervous system factors are now understood to be important in the etiology of temporomandibular disorders (TMD), but knowledge concerning objective markers of central pathophysiology in TMD is lacking. Multivariate analysis techniques like support vector machines (SVMs) could generate important discoveries regarding the expression of pain centralization in TMD. Support vector machines can ...

Teaching Adult Rats Spinalized as Neonates to Walk Using Trunk Robotic Rehabilitation: Elements of Success, Failure, and Dependence.

UNLABELLED: Robot therapy promotes functional recovery after spinal cord injury (SCI) in animal and clinical studies. Trunk actions are important in a...

A connectionist modeling study of the neural mechanisms underlying pain's ability to reorient attention.

Connectionist modeling was used to investigate the brain mechanisms responsible for pain's ability to shift attention away from another stimulus modal...

Deep neural network architectures for forecasting analgesic response.

Response to prescribed analgesic drugs varies between individuals, and choosing the right drug/dose often involves a lengthy, iterative process of tri...

Robotic-assisted laparoscopic hysterectomy for women with endometrial cancer - complications, women´s experiences, quality of life and a health economic evaluation.

This thesis contains four studies all focusing on women with endometrial cancer undergoing robotic-assisted laparoscopic hysterectomy (RALH). Women wi...

Acquisition and extinction of operant pain-related avoidance behavior using a 3 degrees-of-freedom robotic arm.

Ample empirical evidence endorses the role of associative learning in pain-related fear acquisition. Nevertheless, research typically focused on self-...

[Short Text Classification of EMR Based on Entities and Dependency Parser].

Nowadays, text classification and text mining of Electronic Medical Record (EMR) have become the basis of the Big Data research in biomedical fields. ...

KNOWLEDGE-ASSISTED APPROACH TO IDENTIFY PATHWAYS WITH DIFFERENTIAL DEPENDENCIES.

We have previously developed a statistical method to identify gene sets enriched with condition-specific genetic dependencies. The method constructs g...

A Risk Based Neural Network Approach for Predictive Modeling of Blood Glucose Dynamics.

For type 1 diabetes patients, maintaining the blood glucose (BG) at normal values is a challenging task due to e.g. variable insulin reactions, diets,...

Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.

Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on...

Predictive model of synovial membrane degradation using semi-automated morphometry and artificial neural networks.

Gonarthrosis is a degenerative disease that affects mainly older people, but whose incidence has increased significantly in the last decade in populat...

Renoprotective Effects of Shout Camphor Medicinal Mushroom (Taiwanofungus camphorates, Basidiomycetes) Mycelia on Several Media in Mice with Chronic Kidney Disease.

Taiwanofungus camphoratus has been widely used in Taiwan as a folk medicine to prevent and treat liver diseases, diarrhea, abdominal pain, itchy skin,...

[Electroacupuncture Intervention Combined with Anesthetics for Analgesia and Post-surgical Gastrointestinal Recovery in Pneumectomy Patients].

OBJECTIVE: To observe the effect of electroacupuncture (EA) stimulation of bilateral Taichong (LR 3), Yan-glingquan (GB 34), Waiguan (TE 5) and Chize ...

Pharmacodynamics and Pharmacokinetics of Levobupivacaine Used for Epidural Anesthesia in Patients with Liver Dysfunction.

The objective of this study was to study the pharmacodynamics and pharmacokinetics of levobupivacaine used for epidural anesthesia in patients with li...

Tashinone II A-sulfoacid-natrum elevates the pain threshold through inhibiting nuclear factor kappa B pathway in neuropathic cancer pain.

OBJECTIVE: The purpose of this study was to evaluate the effects of Tashinone II A-sulfoacid-natrum on the pain threshold and potential molecular mech...

P052. Patient's subjective judgement on the ease of use, speed of onset of action, efficacy and tolerability of Diclofenac sodium HPβCD (25 mg/mL) solution for subcutaneous injection vs Diclofenac potassium 50 mg for oral solution for the acute treatment of migraine.

Proposal for a Simple and Efficient Monthly Quality Management Program Assessing the Consistency of Robotic Image-Guided Small Animal Radiation Systems.

Modern pre-clinical radiation therapy (RT) research requires high precision and accurate dosimetry to facilitate the translation of research findings ...

Single injection of platelet-rich plasma as a novel treatment of carpal tunnel syndrome.

Both in vitro and in vivo experiments have confirmed that platelet-rich plasma has therapeutic effects on many neuropathies, but its effects on carpal...

[ED50 of Intrathecal Isobaric Bupivacaine with Epidural Volume Extension for Cesarean Delivery].

OBJECTIVE: To determine the 50% effective dose (ED50) of intrathecal isobaric bupivacaine in combined spinal-epidural anaesthesia with epidural volume...