Pain Management

Latest AI and machine learning research in pain management for healthcare professionals.

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Discordance Between Textual Reasoning and Visual Interpretation in Large Language Models for Low Back Pain: Cross-Sectional Quantitative Evaluation and Exploratory Multimodal Stress Test.

BACKGROUND: Large language models (LLMs) are rapidly evolving from text-based agents to multimodal systems capable of interpreting medical images. While their textual reasoning has improved, the safety implications of this shift remain underexplored, specifically regarding the alignment between visual interpretation and textual advice in low back pain (LBP) management. OBJECTIVE: This study aims t...

Aug 20 2026 42622617

Fully automated deep learning for the identification and classification of dental implant brands from multimodal radiographic images.

OBJECTIVES: Accurate radiographic identification of dental implant systems is essential for effective clinical management; however, manual assessment remains time-consuming and susceptible to diagnostic error. Furthermore, conventional computational approaches are constrained by their dependency on manually annotated regions of interest. To overcome these limitations, this study introduces DentalI...

Aug 20 2026 42622711
Skin-to-skin contact improves sleep stability in preterm infants.

BACKGROUND: Sleep supports neurophysiological maturation in preterm infants, yet the impact of developmental care interventions on sleep remains poorl...

Aug 20 2026 42618601
MDAGCN: A multimodal dynamic adaptive graph convolutional network for sleep staging.

Existing deep-learning-based sleep staging frameworks frequently rely on shared multimodal feature extractors, which may overlook modality-specific di...

Aug 19 2026 42616264
Brain network biomarkers for diagnosis and clinical stratification in multiple sclerosis: a longitudinal study integrating individualised structural covariance MRI with high-density EEG.

BACKGROUND: Multiple sclerosis (MS) is increasingly recognised as a disorder of large-scale brain network reorganisation rather than a disease explain...

Aug 19 2026 42617385
AI-Guided Computational Design of Synthetic Microbiota for Next-Generation Immunomodulatory Applications.

The growing recognition of the human microbiome as a key regulator of immune homeostasis has accelerated the application of computational intelligence...

Aug 19 2026 42617743
Artificial Intelligence Analysis of Standard 12-Lead Electrocardiograms for Screening of Symptomatic Diabetic Peripheral Neuropathy.

AIM: To investigate whether artificial intelligence (AI) models trained on standard 12-lead electrocardiograms (ECG) can identify symptom-defined diab...

Aug 19 2026 42618536
An artificial intelligence-driven workflow to detect the macula and quantify retinal ganglion cells in nonhuman primates.

The retinal ganglion cell layer integrates and transmits stimuli from photoreceptors to the central nervous system. Retinal ganglion cell loss is a ha...

Aug 19 2026 42618539
Macrophage Lipid Homeostasis Drives IVDD via a Senescence-Dependent Impairment of Efferocytosis.

Intervertebral disc degeneration (IVDD) is a major contributor to low back pain, but the immune-metabolic events that sustain disc inflammation remain...

Aug 19 2026 42619249
Foundation Model Forecasting of Headache Days in People With Persisting Postconcussion Symptoms.

OBJECTIVES: We aimed to forecast headache in individuals with persisting postconcussion symptoms using foundation machine learning (ML) models and mul...

Aug 18 2026 42611195
Deep learning-derived left ventricular circumferential strain for cardiac MRI diagnosis of acute myocarditis with preserved ejection fraction.

To evaluate the diagnostic performance of deep learning-derived left ventricular circumferential strain (DL-LVCS), a method that reduces operator depe...

Aug 18 2026 42611414
Real-Time Symptom and Wearable Monitoring May Improve Prediction of Postoperative Recovery in Lumbar Spine Surgery Beyond Standard Measures.

BACKGROUND AND OBJECTIVES: Accurately identifying candidates likely to benefit from surgery and addressing modifiable preoperative risk factors are ce...

Aug 18 2026 42611684
ResoMamba-LLM: multimodal physiological signal stress detection for wearable devices via Mamba and LLM reprogramming.

OBJECTIVE: The accuracy of psychological stress detection hinges upon the precision with which models capture complex and variable physiological respo...

Aug 18 2026 42612704
Effectiveness of an artificial intelligence-based self-management intervention to support sick-listed individuals with musculoskeletal disorders in Norway: rationale and protocol for the SmaRTWork randomised controlled trial.

INTRODUCTION: Long-term sickness absence represents a major public health challenge with far-reaching consequences for both individuals and society. M...

Aug 18 2026 42613108
Detecting scoliosis at scale using automated cobb angle analysis in the UK biobank.

PURPOSE: Adult degenerative scoliosis arises after skeletal maturity in an initially normal spine, primarily driven by age-related degeneration. The C...

Aug 17 2026 42606698
A public generalizable AI tool for automated segmentation of coronal brain tissue slabs for 3D neuropathology.

Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs...

Aug 17 2026 42607065
Antimony- and NSAID-Induced Hepatotoxicity at the Molecular Crossroads: Redox, Inflammasome and Programmed Cell-Death Networks as Therapeutic Targets for Natural Hepatoprotective Agents.

Drug- and metal-induced liver damage (DILI/MILI) continues to be a predominant cause of acute hepatic failure globally, with two clinically significan...

Aug 16 2026 42604827
Application of Artificial Intelligence (AI) in cancer symptom management for adult cancer survivors: a scoping review.

BACKGROUND AND AIM: Artificial Intelligence (AI) has been increasingly used in cancer survivorship to support symptom management. This scoping review ...

Aug 15 2026 42603423
Comparison of responses from google and large language models to the top frequently asked questions on lumbar spinal stenosis: an evaluation of accuracy and completeness.

PURPOSE: Lumbar spinal stenosis (LSS) is a common degenerative spinal condition and a leading cause of pain and disability in adults. With increasing ...

Aug 14 2026 42599308
Large language models in spine care and research.

BACKGROUND: Large language models (LLMs) have emerged as powerful transformer-based systems capable of capturing long-range dependencies and complex s...

Aug 14 2026 42599309
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