Pain Management

Latest AI and machine learning research in pain management for healthcare professionals.

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ChatGPT-4 reliability when applied to the regional anesthesia technique sonoanatomy.

BACKGROUND: Ultrasound-guided regional anesthesia is commonly used to enhance perioperative analgesia. However, the technique is limited by inter-operator variability in identifying anatomical structures. Recent advances in artificial intelligence, particularly large language models, have raised the possibility of providing real-time interpretation support. METHODS: This prospective observational ...

Feb 9 2026 41661537

Machine Learning Model Development and Validation in Individuals With Suggestive Hypersensitivity to Nonsteroidal Anti-inflammatory Drugs.

BACKGROUND AND OBJECTIVES: Nonsteroidal anti-inflammatory drugs (NSAIDs) are the main triggers of drug hypersensitivity reactions (HSRs). NSAID-induced HSRs constitute a significant health problem owing to their prevalence, phenotypes, mechanisms of action, and complex diagnosis. However, in around 60% of individuals attending for suggestive NSAID-induced HSRs, this diagnosis is ruled out. Patient...

Feb 9 2026 41661666
Prehospital Blood Collection for High Sensitivity Cardiac Troponin Measurement in Patients with Acute Chest Pain.

OBJECTIVES: High sensitivity cardiac troponin (hs-cTn) measures are used in the emergency department (ED) to evaluate patients with acute chest pain. ...

Feb 9 2026 41662493
Does generative AI dependence foster creativity? Evidence from sports undergraduates.

As an emerging technological tool, generative AI profoundly reshapes higher education teaching and learning processes. Creativity, as a key component ...

Feb 9 2026 41662394
Glymphatic dysfunction in trigeminal neuralgia: A multimodal MRI study.

BACKGROUND: Trigeminal neuralgia (TN) has traditionally been attributed to peripheral neurovascular compression at the trigeminal nerve root entry zon...

Feb 8 2026 41666986
Readability, Accuracy, and Lexical Diversity of New ChatGPT Models for Common Carpal Tunnel Syndrome Questions.

BACKGROUND: Carpal tunnel syndrome (CTS) is a prevalent neuropathy in hand surgery that significantly affects people's quality of life. Frequently, pa...

Feb 8 2026 41656595
CGLK-GNN : A connectome generation network with large kernels for GNN based Alzheimer's disease analysis.

Alzheimer's disease (AD) is a currently incurable neurodegenerative disease, with early detection representing a high research priority. AD is charact...

Feb 7 2026 41687240
BackTracker: Machine learning to identify kinematic phenotypes for personalised exercise management in non-specific low back pain.

BACKGROUND: Low back pain (LBP) is a leading cause of global disability. Most cases are non-specific (NSLBP) and lack identifiable causes. Early activ...

Feb 7 2026 41689880
Factors Associated with Machine Learning-Based Predictions of Retinal Aging Using Teleretinal Screening Images from Patients with Diabetes.

PURPOSE: To identify factors associated with accelerated retinal aging based on machine learning predictions of age using fundus images from teleretin...

Feb 7 2026 41853569
CT- DImQ: An open-access platform for image quality assessment of CT systems- application to CT values and noise characterization in 3D-printed anthropomorphic thorax phantoms.

PURPOSE: To present an open access platform for CT image quality assessment combined with anthropomorphic phantoms. To promote the accessibility of an...

Feb 7 2026 41655504
Enhancing Anesthetic Depth Assessment via Unsupervised Machine Learning in Processed Electroencephalography Analysis: Novel Methodological Study.

BACKGROUND: General anesthesia comprises 3 essential components-hypnosis, analgesia, and immobility. Among these, maintaining an appropriate hypnotic ...

Feb 6 2026 41650286
Combating Antiviral Drug Resistance: A Multipronged Strategy.

ConspectusViral proteases are essential enzymes required for viral replication and assembly, making them prime antiviral drug targets. However, under ...

Feb 6 2026 41650319
Computational Advances in RNA-Small Molecule Binding Site Prediction.

RNA-small molecule interactions are fundamental to cellular regulation and have emerged as highly attractive therapeutic targets. Despite their potent...

Feb 5 2026 41654089
Smelling decides: fMRI evidence reveals the influence of olfactory stimuli on risky decision-making.

BACKGROUND AND PURPOSE: Olfactory stimuli are known to have a significant effect on cognitive functions. However, their effect on risky decision-makin...

Feb 5 2026 41654178
Attitudes toward AI in health- and non-health-related contexts: Context matters, not mood or perceived social support.

As artificial intelligence (AI) systems increasingly permeate healthcare and daily life, understanding the factors that shape attitudes toward their u...

Feb 5 2026 41650897
TrkA abundance is increased in cutaneous nerves in bortezomib-induced neuropathy.

Tropomyosin receptor kinase A (TrkA), a high-affinity receptor for nerve growth factor (NGF), is implicated in nociception and local angiogenesis. We ...

Feb 5 2026 41644104
Integrating Regenerative Therapies and Artificial Intelligence for Precision Management of Diabetic Foot Ulcers.

SIGNIFICANCE: Diabetic foot ulcers (DFUs) represent one of the most devastating complications of diabetes, leading to high rates of amputation and mor...

Feb 5 2026 41644477
Development and validation of a fentanyl quantification model for drug checking services.

BACKGROUND: Drug checking services are becoming increasingly popular. Despite the significant variability in fentanyl concentrations observed in the u...

Feb 4 2026 41704559
Ultrasound-guided microwave ablation for breast tumors: current status and future perspectives.

Ultrasound (US)-guided microwave ablation (MWA) has emerged as a promising minimally invasive therapy for both benign and malignant breast tumors. Thi...

Feb 4 2026 41635204
Protocol for Personalised Prediction of Persistent Postsurgical Pain.

INTRODUCTION: Persistent postsurgical pain (PPSP) affects up to 15% of patients after major surgery, impairing physical function, quality of life and ...

Feb 4 2026 41638723
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