Latest AI and machine learning research in pain management for healthcare professionals.
Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show that the gut microbiota influences and is influenced by anticancer drugs, data from patients paired with careful side effect monitoring remains limited. Here, we investigate capecitabine (CAP)-microbiome interactions through longitudinal metagenomic sequencing of stool from 56 advanced colorectal canc...
Graphs are widely used to model interconnected systems, offering powerful tools for data representation and problem-solving. However, their reliance on pairwise, single-type, and static connections limits their expressive capacity. Recent developments extend this foundation through higher-order structures, such as hypergraphs, multilayer, and temporal networks, which better capture complex real-wo...
BACKGROUND: Recent studies evaluating frequently asked questions (FAQs) on labor epidural analgesia (LEA) only used generic questions without incorpor...
Substance use disorders (SUDs), including Alcohol Use Disorder, are pressing global public health problems. Executive functions (EFs) are prominently ...
Microneedles (MNs) offer a minimally invasive alternative to conventional patch-based and injection-based drug delivery methods. By bypassing first-pa...
Automatic pain assessment for non-communicative children is in high demand. However, the availability of related training datasets remains limited. Th...
BACKGROUND/OBJECTIVES: Quality of life (QoL) is negatively affected in people with all-over pain. Widespread pain has a negative impact on physical fu...
BACKGROUND: Human immunodeficiency virus (HIV), while now manageable as a chronic health condition with highly active antiretroviral therapy (HAART), ...
Carpal Tunnel Syndrome (CTS) is the most common entrapment neuropathy, frequently presenting with pain, numbness, and muscle weakness due to median ne...
Postoperative pain, anxiety, and psychological distress significantly impact surgical recovery, yet conventional management strategies often lack pers...
Chronic pain is a complex and multidimensional condition that disrupts both physical function and cognitive processing, creating a bidirectional cycle...
A 25-year-old previously healthy man presents to the clinic with a severe headache after cocaine consumption. Physical examination revealed acromegalo...
BACKGROUND: Poppy Active Pharmaceutical Ingredients (APIs) are mainly used in the production of antitussives, analgesics, and other preparations. The ...
BACKGROUND: Trigeminal activation and sensitisation involved in chronic inflammatory orofacial pain share several similarities with headaches, includi...
Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surgical procedures, as these symptoms greatly impact ...
A randomized, blinded, placebo-controlled crossover study was performed with eight professional working dogs to evaluate the pharmacokinetics and phar...
BACKGROUND: Migraine ranks as the second-leading cause of global neurological disability, affecting approximately 1.1Â billion individuals worldwide wi...
Migraine has an assumed polygenic basis, but the genetic risk variants identified in genome-wide association studies only explain a proportion of the ...
PURPOSE: Pain consists of biological, psychological, and sociological elements that are influenced by the aging process. Pain management in older adul...
INTRODUCTION: Lumbar prolapsed disc (LPD) is a leading cause of low back pain, contributing significantly to global disability and healthcare burden. ...