Pancreatic Diseases

Retraction notice to "Molecular structure and mechanism of protein MSMB, TPPP3, SPI1: Construction of novel 4 pancreatic cancer-related protein signatures model based on machine learning" [Int. J. Biol. Macromol. 307 (2025) 142075].

Organelle proteomics of human, neonatal pig, healthy and diabetic mouse islets.

Pancreatic islets, in which β cells constitute 50%-80% of the endocrine mass, are the body's site for glucose-regulated insulin secretion. Pancreatic islet dysfunction is a hallmark of type 2 diabetes. Nevertheless, the molecular changes that impair their function remain insufficiently understood. To determine how islet cellular organization supports function and how it deteriorates in disease, we...

Histology-derived prediction of a stromal remodeling program in pancreatic ductal adenocarcinoma with transcriptomic and spatial validation.

OBJECTIVE: To develop and validate a histology-based model for predicting a stromal stiffness-related molecular surrogate in pancreatic ductal adenoca...

Recycled Aggregate Green Concrete with Graphene Oxide-Coated PVA Fibers: Performance Improvement and Life Cycle Evaluation.

Recycled aggregate concrete provides a sustainable route to reduce natural aggregate consumption and promote the recycling of construction and demolit...

Development and external validation of a machine learning model for predicting tigecycline-associated drug-induced liver injury.

Tigecycline (TGC) is widely used to treat severe multidrug-resistant infections but can cause drug-induced liver injury. Existing prediction studies f...

Diagnostic performance of ¹⁸F-FDG PET/CT radiomics-based machine learning models for pancreatic lesion characterisation: Comparison with visual assessment and evaluation of human-radiomics synergy.

PURPOSE: We aimed to evaluate the diagnostic performance of ¹⁸F-FDG PET/CT-derived radiomics-based machine learning models for differentiating maligna...

Developing a Histology-Based Artificial Intelligence Biomarker to Predict Adjuvant Chemotherapy Benefit in Pancreatic Cancer.

PURPOSE: The choice of adjuvant chemotherapy in pancreatic ductal adenocarcinoma (PDAC) is mainly guided by patients' general condition. We hypothesiz...

Highly sensitive self-powered pressure sensor with high power output based on electrochemical reactions for rehabilitation monitoring.

Self-powered electrochemical pressure sensors have aroused considerable research interest owing to their capability of sensing both static and dynamic...

Classifying Diabetic and Healthy β-Cells in Type 2 Diabetes Using Machine Learning on Single-Cell RNA Sequencing Data.

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production or function. Two main forms...

Portal vein resection in pancreatic cancer: from technical feasibility to biological patient selection.

INTRODUCTION: Portal vein resection (PVR) has become an established component of pancreatic cancer surgery for selected patients with portal vein-supe...

Personalized cancer vaccines: bridging immune-oncology and precision medicine for advanced therapeutics.

Despite advancements in therapeutic cancer vaccines, clinical translation has been hindered by limited efficacy, with Sipuleucel-T remaining the only ...

Reading Between the Voxels: Artificial Intelligence Detection of Occult Pancreatic Cancer.

Thermodynamics and Kinetics of CO2 Sorption and Water Remediation on Waste Polyurethane Foam-Derived Hybrids.

Converting waste into dual-function materials for both atmospheric and aqueous remediation remains a formidable challenge in realizing a circular econ...

Natural Language Processing to Identify Substance Use in Electronic Health Records: A Scoping Review.

BACKGROUND: This scoping review aimed to characterize natural language processing (NLP) techniques deployed for identifying substance use in electroni...

Eco-benign synthesis of spent vegetable oil-based biodiesel using thermally modified nanocrystalline snail shell catalysts: experimental, modeling and computational studies.

The quest to mitigate the critical challenges in the global energy landscape and carbon emission crisis and promote sustainable energy practices calls...

Artificial intelligence-based model for identifying anatomical and surgical structures in the videos of laparoscopic left hemicolectomy.

BACKGROUND: Precise surgical procedures are critical to improving the survival outcomes for colon cancer patients. Currently, there is no dedicated in...

AI-driven tumor heterogeneity quantification and survival prediction in pancreatic ductal adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies worldwide, and accurate prognostic prediction remains highly challengin...

Exosomes in cancer drug resistance: dual roles in therapy failure and emerging precision therapeutics.

Exosomes play a key role in cancer, functioning both as drivers of drug resistance and as tools for therapy. Tumor-derived exosomes facilitate interce...

A clinically interpretable model for predicting pharyngocutaneous fistula after total laryngectomy.

BACKGROUND: Pharyngocutaneous fistula (PCF) is a frequent complication following total laryngectomy. While various risk models exist, their practical ...

Device-measured movement behaviours and cancer incidence in a population sample of UK adults: Dual 24-hour analyses of postural and intensity compositions.

BACKGROUND: Insufficient physical activity (PA) and excessive sedentary behaviour is associated with several cancers. Personalised approaches to incre...