Pancreatic Diseases

Predicting and analyzing the dielectric constant of polyvinyl alcohol reinforced with different nanofillers using machine learning modeling.

Polyvinyl alcohol (PVA) is a widely used polymer in many applications. The nanoparticles' incorporat...

CHRNA5 orchestrates tumorigenesis and immune invasion through the CaMKII/AKT/NF-κB-CCL20 axis in pancreatic ductal adenocarcinoma.

AIMS: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by poo...

Leveraging pretrained vision transformers for classifying alcohol use disorder using raw resting-state EEG.

Alcohol Use Disorder (AUD) is a prevalent neuropsychiatric condition affecting about 28 million adul...

Structured Schemas for Provenance-Rich, LLM-Assisted QSP Model Calibration.

Quantitative systems pharmacology (QSP) models require calibration data from literature, yet manual ...

Deep learning-based detection of acute pancreatitis on abdominal contrast-enhanced CT.

OBJECTIVE: We developed and evaluated a deep learning (DL) model for image-based detection of acute ...

Unraveling the roles of DKK1 and S100P in pancreatic ductal adenocarcinoma: Insights from machine learning, single-cell/spatial transcriptomics, and functional validation.

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a 5-year survival rat...

AI-driven discovery and validation of a GIPC1 PDZ domain inhibitor for pancreatic ductal adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) remains highly aggressive, with a five-year survival rate un...

Three-class obstructive sleep apnea severity assessment: a parallel AHI and ODI explainable artificial intelligence framework using craniofacial-enriched clinical data.

BACKGROUND: Machine learning models for Obstructive Sleep Apnea (OSA) diagnosis have largely inherit...

Real World Evaluation of AI-Based Tumor Cell Content Quantification for Molecular Tumor Profiling.

PURPOSE: Repeated evidence demonstrates limited reproducibility and accuracy of the visual quantific...

Integrating Multimodal Data and Genomics for a Comprehensive Assessment of Cardiovascular Aging and Its Impact.

BACKGROUND: Age-related structural and functional remodeling of the heart and vessels increases card...

Impact of image reconstruction algorithms on histogram analysis of iodine concentration for assessing chemotherapy response in pancreatic ductal adenocarcinoma.

PURPOSE: To evaluate the impact of image reconstruction algorithms on histogram analysis of iodine c...

Neural networks improve repeatability of intravoxel incoherent motion (IVIM) parameter estimation in pancreatic diffusion-weighted MRI.

Intravoxel incoherent motion (IVIM) analysis in diffusion-weighted MRI (DWI-MRI) shows potential for...

Rewiring immunometabolism in hepato-biliary-pancreatic cancers: Unraveling TME-mediated metabolic suppression and advancing next-generation immunotherapeutic approaches.

Hepato-biliary-pancreatic cancers, notorious for their pronounced heterogeneity and poor prognosis, ...

Retraction notice to "Molecular structure and mechanism of protein MSMB, TPPP3, SPI1: Construction of novel 4 pancreatic cancer-related protein signatures model based on machine learning" [Int. J. Biol. Macromol. 307 (2025) 142075].

Organelle proteomics of human, neonatal pig, healthy and diabetic mouse islets.

Pancreatic islets, in which β cells constitute 50%-80% of the endocrine mass, are the body's site fo...

Histology-derived prediction of a stromal remodeling program in pancreatic ductal adenocarcinoma with transcriptomic and spatial validation.

OBJECTIVE: To develop and validate a histology-based model for predicting a stromal stiffness-relate...

Recycled Aggregate Green Concrete with Graphene Oxide-Coated PVA Fibers: Performance Improvement and Life Cycle Evaluation.

Recycled aggregate concrete provides a sustainable route to reduce natural aggregate consumption and...

Development and external validation of a machine learning model for predicting tigecycline-associated drug-induced liver injury.

Tigecycline (TGC) is widely used to treat severe multidrug-resistant infections but can cause drug-i...

Diagnostic performance of ¹⁸F-FDG PET/CT radiomics-based machine learning models for pancreatic lesion characterisation: Comparison with visual assessment and evaluation of human-radiomics synergy.

PURPOSE: We aimed to evaluate the diagnostic performance of ¹⁸F-FDG PET/CT-derived radiomics-based m...

Developing a Histology-Based Artificial Intelligence Biomarker to Predict Adjuvant Chemotherapy Benefit in Pancreatic Cancer.

PURPOSE: The choice of adjuvant chemotherapy in pancreatic ductal adenocarcinoma (PDAC) is mainly gu...

Highly sensitive self-powered pressure sensor with high power output based on electrochemical reactions for rehabilitation monitoring.

Self-powered electrochemical pressure sensors have aroused considerable research interest owing to t...