Neurology

Parkinson's Disease

Latest AI and machine learning research in parkinson's disease for healthcare professionals.

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PDON: Parkinson's disease ontology for representation and modeling of the Parkinson's disease knowledge domain.

BACKGROUND: Despite the unprecedented and increasing amount of data, relatively little progress has been made in molecular characterization of mechanisms underlying Parkinson's disease. In the area of Parkinson's research, there is a pressing need to integrate various pieces of information into a meaningful context of presumed disease mechanism(s). Disease ontologies provide a novel means for orga...

Sep 22 2015 26395080

A Method for Automatic and Objective Scoring of Bradykinesia Using Orientation Sensors and Classification Algorithms.

Correct assessment of bradykinesia is a key element in the diagnosis and monitoring of Parkinson's disease. Its evaluation is based on a careful assessment of symptoms and it is quantified using rating scales, where the Movement Disorders Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) is the gold standard. Regardless of their importance, the bradykinesia-rel...

Sep 18 2015 26394414
A Fuzzy Inference System for Closed-Loop Deep Brain Stimulation in Parkinson's Disease.

Parkinsons disease is a complex neurodegenerative disorder for which patients present many symptoms, tremor being the main one. In advanced stages of ...

Sep 18 2015 26385550
Machine learning classification of medication adherence in patients with movement disorders using non-wearable sensors.

Medication non-adherence is a major concern in the healthcare industry and has led to increases in health risks and medical costs. For many neurologic...

Sep 8 2015 26406881
Trans-oral robotic cleft surgery (TORCS) for palate and posterior pharyngeal wall reconstruction: A feasibility study.

BACKGROUND/AIM: Robot-assisted surgery has become increasingly routine, replacing open and laparoscopic techniques in certain domains, with recent ext...

Sep 4 2015 26409954
Cost-efficient FPGA implementation of basal ganglia and their Parkinsonian analysis.

The basal ganglia (BG) comprise multiple subcortical nuclei, which are responsible for cognition and other functions. Developing a brain-machine inter...

Aug 10 2015 26318085
Control of a Supernumerary Robotic Hand by Foot: An Experimental Study in Virtual Reality.

In the operational theater, the surgical team could highly benefit from a robotic supplementary hand under the surgeon's full control. The surgeon may...

Jul 30 2015 26225938
LC-HRMS determination of piperine on rat dried blood spots: A pharmacokinetic study.

A liquid chromatography-high resolution mass spectrometry (LC-HRMS) method was developed and validated for the determination of piperine (PPR) on drie...

Jul 20 2015 29403958
Machine Learning Approach to Optimizing Combined Stimulation and Medication Therapies for Parkinson's Disease.

BACKGROUND: Deep brain stimulation (DBS) of the subthalamic region is an established therapy for advanced Parkinson's disease (PD). However, patients ...

Jun 15 2015 26140956
Identifying the Basal Ganglia network model markers for medication-induced impulsivity in Parkinson's disease patients.

Impulsivity, i.e. irresistibility in the execution of actions, may be prominent in Parkinson's disease (PD) patients who are treated with dopamine pre...

Jun 4 2015 26042675
Overground robot assisted gait trainer for the treatment of drug-resistant freezing of gait in Parkinson disease.

Freezing of Gait (FOG) is a frequent and disabling feature of Parkinson disease (PD). Gait rehabilitation assisted by electromechanical devices, such ...

May 29 2015 26048047
Evaluation by Expert Dancers of a Robot That Performs Partnered Stepping via Haptic Interaction.

Our long-term goal is to enable a robot to engage in partner dance for use in rehabilitation therapy, assessment, diagnosis, and scientific investigat...

May 20 2015 25993099
Discriminative analysis of Parkinson's disease based on whole-brain functional connectivity.

Recently, there has been an increasing emphasis on applications of pattern recognition and neuroimaging techniques in the effective and accurate diagn...

Apr 17 2015 25885059
A small-scale hyperacute compound eye featuring active eye tremor: application to visual stabilization, target tracking, and short-range odometry.

In this study, a miniature artificial compound eye (15 mm in diameter) called the curved artificial compound eye (CurvACE) was endowed for the first t...

Feb 25 2015 25712307
Robotic general surgery: current practice, evidence, and perspective.

BACKGROUND: Robotic technology commenced to be adopted for the field of general surgery in the 1990s. Since then, the da Vinci surgical system (Intuit...

Feb 18 2015 25854502
Machine learning models for the differential diagnosis of vascular parkinsonism and Parkinson's disease using [(123)I]FP-CIT SPECT.

PURPOSE: The study's objective was to develop diagnostic predictive models using data from two commonly used [(123)I]FP-CIT SPECT assessment methods: ...

Aug 14 2014 25120041
Robot-assisted gait training is not superior to balance training for improving postural instability in patients with mild to moderate Parkinson's disease: a single-blind randomized controlled trial.

OBJECTIVE: The main aim was to compare robotic gait training vs. balance training for reducing postural instability in patients with Parkinson's disea...

Jul 31 2014 25082957
Markerless Motion Capture Reveals Movement Abnormalities in Isolated REM Sleep Behavior Disorder

Objective and scalable approaches for detecting subtle motor impairment in isolated REM sleep behavior disorder (iRBD), a prodromal stage of Parkinson...

StainPresetNet: Stain Preset Network for Fast Multi-to-Multi Stain Normalization

Stain normalization reduces color variations caused by variations in staining protocols and imaging conditions, thereby enhancing computer-aided diagn...

Sep 1 2026 2609.01146v1
Impact of Axon Model Complexity on Deep Brain Stimulation: A Comparative Analysis of MRG and Cohen Double-Cable Models

Deep brain stimulation (DBS) modeling relies heavily on biophysical neuron models to estimate neural activation thresholds and predict stimulation spr...

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