Neurology

Parkinson's Disease

Latest AI and machine learning research in parkinson's disease for healthcare professionals.

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On the Relevance of Clinical Assessment Tasks for the Automatic Detection of Parkinson's Disease Medication State from Speech

The automatic identification of medication states of Parkinson's disease (PD) patients can assist clinicians in monitoring and scheduling personalized treatments, as well as studying the effects of medication in alleviating the motor symptoms that characterize the disease. This paper explores speech as a non-invasive and accessible biomarker for identifying PD medication states, introducing a no...

Medication versus globus pallidus internus deep brain stimulation in Parkinson's disease with deep learning video analysis of finger tapping.

In advanced Parkinson's disease (PD), considerable number of patients receive deep brain stimulation (DBS) surgery, to alleviate symptoms not readily controlled by medication. However, the differential effects of medication and DBS on improving motor symptoms, especially for DBS targeting the globus pallidus internus (GPi), have not been explored in sufficient detail. We studied the finger tapping...

May 21 2025 40394036
Digital Biomarkers for Parkinson Disease: Bibliometric Analysis and a Scoping Review of Deep Learning for Freezing of Gait.

BACKGROUND: With the rapid development of digital biomarkers in Parkinson disease (PD) research, it has become increasingly important to explore the c...

May 20 2025 40392578
Guiding Diffusion with Deep Geometric Moments: Balancing Fidelity and Variation

Text-to-image generation models have achieved remarkable capabilities in synthesizing images, but often struggle to provide fine-grained control ove...

BenSParX: A Robust Explainable Machine Learning Framework for Parkinson's Disease Detection from Bengali Conversational Speech

Parkinson's disease (PD) poses a growing global health challenge, with Bangladesh experiencing a notable rise in PD-related mortality. Early detecti...

AI-DBS study: protocol for a longitudinal prospective observational cohort study of patients with Parkinson's disease for the development of neuronal fingerprints using artificial intelligence.

INTRODUCTION: Deep brain stimulation (DBS) is a proven effective treatment for Parkinson's disease (PD). However, titrating DBS stimulation parameters...

May 16 2025 40379316
Co-Designing a "win-win" in Predictive AI: First Results from Interviews and Focus Groups with Persons with Parkinson's Disease.

This study explored the perspectives of people with Parkinson's disease (PwP) involved in the co-design of AI tools for PD care. The aim was to unders...

May 15 2025 40380436
DLO-Splatting: Tracking Deformable Linear Objects Using 3D Gaussian Splatting

This work presents DLO-Splatting, an algorithm for estimating the 3D shape of Deformable Linear Objects (DLOs) from multi-view RGB images and grippe...

Predicting dementia in people with Parkinson's disease.

Parkinson's disease (PD) exhibits a variety of symptoms, with approximately 25% of patients experiencing mild cognitive impairment and 45% developing ...

May 13 2025 40360514
Baseline [F]FP-CIT PET-based deep learning prediction of levodopa-induced dyskinesia in Parkinson's disease.

We aimed to develop a convolutional neural network (CNN) model with multi-task learning to predict the onset of levodopa-induced dyskinesia (LID) in p...

May 12 2025 40355487
Impact of canny edge detection preprocessing on performance of machine learning models for Parkinson's disease classification.

This study investigates the classification of individuals as healthy or at risk of Parkinson's disease using machine learning (ML) models, focusing on...

May 12 2025 40355628
Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases.

Neurodegenerative diseases (NDD) are characterized by the progressive loss of neurons and the impairment of cellular functions. Messenger RNA (mRNA) h...

May 10 2025 40120689
Deep learning for Parkinson's disease classification using multimodal and multi-sequences PET/MR images.

BACKGROUND: We aimed to use deep learning (DL) techniques to accurately differentiate Parkinson's disease (PD) from multiple system atrophy (MSA), whi...

May 9 2025 40346391
AI-Driven Advances in Parkinson's Disease Neurosurgery: Enhancing Patient Selection, Trial Efficiency, and Therapeutic Outcomes.

Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by motor and non-motor dysfunctions that severely compromise patients' qua...

May 9 2025 40426665
Identifying Common Disease Trajectories of Progressive Supranuclear Palsy with Electronic Health Records.

BACKGROUND: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder characterized by parkinsonism and impairments in balance, langua...

May 9 2025 40344390
A Multi-Modal Graph Neural Network Framework for Parkinson's Disease Therapeutic Discovery.

Parkinson's disease (PD) is a complex neurodegenerative disorder lacking effective disease-modifying treatments. In this study, we integrated large-sc...

May 7 2025 40362692
A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos

Parkinson's disease (PD) is a neurodegenerative disorder, manifesting with motor and non-motor symptoms. Depressive symptoms are prevalent in PD, af...

Machine-Learning-Powered Neural Interfaces for Smart Prosthetics and Diagnostics

Advanced neural interfaces are transforming applications ranging from neuroscience research to diagnostic tools (for mental state recognition, tremo...

PointExplainer: Towards Transparent Parkinson's Disease Diagnosis

Deep neural networks have shown potential in analyzing digitized hand-drawn signals for early diagnosis of Parkinson's disease. However, the lack of...

Humans can learn to detect AI-generated texts, or at least learn when they can't

This study investigates whether individuals can learn to accurately discriminate between human-written and AI-produced texts when provided with imme...

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