Neurology

Parkinson's Disease

Latest AI and machine learning research in parkinson's disease for healthcare professionals.

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Radar Network for Gait Monitoring: Technology and Validation

In recent years, radar-based devices have emerged as an alternative approach for gait monitoring. However, the radar configuration and the algorithms used to extract the gait parameters often differ between contributions, lacking a systematic evaluation of the most appropriate setup. Additionally, radar-based studies often exclude motorically impaired subjects, leaving it unclear whether the exi...

Artificial intelligence-enabled detection and assessment of Parkinson's disease using multimodal data: A survey

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective biomarkers for diagnosing PD, assessing its severity, or tracking its progression. Numerous AI algorithms are now being used for PD diagnosis and treatment, c...

Lifespan tree of brain anatomy: diagnostic values for motor and cognitive neurodegenerative diseases

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with arti...

Enhanced LSTM by Attention Mechanism for Early Detection of Parkinson's Disease through Voice Signals

Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as ...

Mixed Integer Linear Programming for Active Contact Selection in Deep Brain Stimulation

Deep brain stimulation (DBS) programming remains a complex and time-consuming process, requiring manual selection of stimulation parameters to achie...

SincPD: An Explainable Method based on Sinc Filters to Diagnose Parkinson's Disease Severity by Gait Cycle Analysis

In this paper, an explainable deep learning-based classifier based on adaptive sinc filters for Parkinson's Disease diagnosis (PD) along with determ...

Generative Autoregressive Transformers for Model-Agnostic Federated MRI Reconstruction

Although learning-based models hold great promise for MRI reconstruction, single-site models built on limited local datasets often suffer from poor ...

Identification of Depression Subtypes in Parkinson's Disease Patients via Structural MRI Whole-Brain Radiomics: An Unsupervised Machine Learning Study.

OBJECTIVE: Current clinical evaluation may tend to lack precision in detecting depression in Parkinson's disease (DPD). Radiomics features have gradua...

Feb 1 2025 39915918
Analysis of Two Neuroanatomical Subtypes of Parkinson's Disease and Their Motor Progression Based on Semi-Supervised Machine Learning.

BACKGROUND: The high heterogeneity of Parkinson's disease (PD) hinders personalized interventions. Brain structure reflects damage and neuroplasticity...

Feb 1 2025 39953811
Machine Learning Strategies for Parkinson Tremor Classification Using Wearable Sensor Data

Parkinson's disease (PD) is a neurological disorder requiring early and accurate diagnosis for effective management. Machine learning (ML) has emerg...

IRONMAP: Iron Network Mapping and Analysis Protocol for Detecting Over-Time Brain Iron Abnormalities in Neurological Disease

Pathologically altered iron levels, detected using iron-sensitive MRI techniques such as quantitative susceptibility mapping (QSM), are observed in ...

Distinguishing Parkinson's Patients Using Voice-Based Feature Extraction and Classification

Parkinson's disease (PD) is a progressive neurodegenerative disorder that impacts motor functions and speech characteristics This study focuses on d...

EVolutionary Independent DEtermiNistiC Explanation

The widespread use of artificial intelligence deep neural networks in fields such as medicine and engineering necessitates understanding their decis...

Identification of CXCR4 inhibitory activity in natural compounds using cheminformatics-guided machine learning algorithms.

Neurodegenerative disorders are characterised by progressive damage to neurons that leads to cognitive impairment and motor dysfunction. Current treat...

Jan 8 2025 39985292
Towards a Generalizable Speech Marker for Parkinson's Disease Diagnosis

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Ea...

A Self-supervised Diffusion Bridge for MRI Reconstruction

Diffusion bridges (DBs) are a class of diffusion models that enable faster sampling by interpolating between two paired image distributions. Trainin...

Machine Learning-Based Differential Diagnosis of Parkinson's Disease Using Kinematic Feature Extraction and Selection

Parkinson's disease (PD), the second most common neurodegenerative disorder, is characterized by dopaminergic neuron loss and the accumulation of ab...

Matrix effects influence biochemical signatures and metabolite quantification in dried blood spots

Dried blood spots (DBS) represent a convenient clinical sample material, offering low infection risk, easy transport, and long-term metabolite stabili...

Non-invasive Ultrasonic Neuromodulation of the Human Nucleus Accumbens Impacts Reward Sensitivity

Precisely neuromodulating deep brain regions could bring transformative advancements in both neuroscience and treatment. We demonstrate that non-invas...

Structure-based Generation of a Secondary Nucleation Inhibitor in α-Synuclein Aggregation Using a Conditional Diffusion Model

The process of α-synuclein aggregation results in the formation of amyloid fibrils, which accumulate in the brain of patients affected by Parkinson’s ...

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