Parkinson's Disease

Robot-assisted gait training versus treadmill training in patients with Parkinson's disease: a kinematic evaluation with gait profile score.

The purpose of this study was to quantitatively compare the effects, on walking performance, of end-effector robotic rehabilitation locomotor training versus intensive training with a treadmill in Parkinson's disease (PD). Fifty patients with PD were randomly divided into two groups: 25 were assigned to the robot-assisted therapy group (RG) and 25 to the intensive treadmill therapy group (IG). The...

Classification of Movement of People with Parkinsons Disease Using Wearable Inertial Movement Units and Machine Learning.

In this work, inertial movement units were placed on people with Parkinsons disease (PwPD) who subsequently performed a standard test of walking endurance (six-minute walk test - 6MWT). Five devices were placed on each the limbs and small of the back. These devices captured the acceleration and rotational motion while the person walked as far as they can in six minutes. The wearable devices can ob...

Accidental Overdose of Oral Cyclosporine in Haematopoietic Stem Cell Transplantation: A Case Report and Literature Review.

A 26-year-old woman developed symptoms of acute toxicity during cyclosporine (CsA) therapy for graft-versus-host disease prophylaxis. The standard reg...

Classification of Parkinson's Disease Gait Using Spatial-Temporal Gait Features.

Quantitative gait assessment is important in diagnosis and management of Parkinson's disease (PD); however, gait characteristics of a cohort are dispe...

[Fluorescence enhancement of flavoxate hydrochloride in alkali solution and its application in pharmaceutical analysis].

Fluorescence enhancement reaction of flavoxate hydrochloride (FX) in strong alkali solution was studied, the mechanism of the reaction was investigate...

Multistep prediction of physiological tremor based on machine learning for robotics assisted microsurgery.

For effective tremor compensation in robotics assisted hand-held device, accurate filtering of tremulous motion is necessary. The time-varying unknown...

In vivo measurement of the frame-based application accuracy of the Neuromate neurosurgical robot.

OBJECT: The application accuracy of the Neuromate neurosurgical robot has been validated in vitro but has not been evaluated in vivo for deep brain st...

Towards an expert system for accurate diagnosis and progress monitoring of Parkinson's disease.

While Parkinson's disease is a chronic and progressive movement disorder, no one can predict which symptoms will affect an individual patient. At the ...

Chat-Bots for People with Parkinson's Disease: Science Fiction or Reality?

People with Parkinson's disease are known to have difficulties in language and communication. This paper proposes the use of an artificial conversatio...

Design of a quasi-passive 3 DOFs ankle-foot wearable rehabilitation orthosis.

Muscular rigidity and atrophy caused by long-term underactivity usually lead to foot drop, strephenopodia, foot extorsion or some other complications ...

Lion's Mane, Hericium erinaceus and Tiger Milk, Lignosus rhinocerotis (Higher Basidiomycetes) Medicinal Mushrooms Stimulate Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina: An In Vitro Study.

Neurodegenerative disease is defined as a deterioration of the nervous system in the intellectual and cognitive capabilities. Statistics show that mor...