Latest AI and machine learning research in pathology for healthcare professionals.
Long-range intercellular communication is essential for multicellular biological systems to regulate multiscale cell-cell interactions and maintain life. Growing evidence suggests that intercellular calcium waves (ICWs) act as a class of long-range signals that influence a broad spectrum of cellular functions and behaviors. Importantly, mechanical signals, ranging from single-molecule-scale to tis...
Cartilage tissue engineering (CTE) is an advancing field focused on developing biomimetic scaffolds to overcome cartilage's inherently limited self-repair capacity. Smart hydrogels (SHs) have gained prominence among the various scaffold materials due to their ability to modulate cellular behavior through tunable mechanical and biochemical properties. These hydrogels respond dynamically to external...
Although iron is an essential element for vital body functions, iron overload (IO) is accompanied by significant cellular damage due to its accumulati...
To evaluate the diagnostic performance of artificial intelligence (AI) in detecting root canal orifices using images captured with a dental operating ...
The histopathologic evaluation of regulatory toxicity studies using artificial intelligence (AI) has the potential to increase study efficiency. For e...
Senescence is a pivotal cellular process, which also plays a major role in development, immune regulation, tissue repair, and aging, triggered by stre...
Virtual staining of tissue offers a powerful tool for transforming label-free microscopy images of unstained tissue into equivalents of histochemicall...
Multiplexed imaging techniques require identifying different cell types in the tissue. To utilize their potential for cellular and molecular analysis,...
INTRODUCTION: This study compared the diagnostic accuracy of interproximal caries detection using intraoral bitewing radiographs, assessed by both hum...
BACKGROUND: Echocardiography is the most common modality for assessing cardiac structure and function. While cardiac magnetic resonance (CMR) imaging ...
Atypia of Undetermined Significance (AUS), classified as Category III in the Bethesda Thyroid Cytopathology Reporting System, presents significant dia...
Forensic investigation of child homicides presents unique challenges due to the vulnerability of children and the complexity of distinguishing betwee...
Breast cancer diagnosis heavily relies on histopathological assessment, which is prone to subjectivity and inefficiency, especially with whole-slide ...
Prostate cancer (PCa) is a major, and increasingly global, health concern with current screening and diagnostic tools' severe limitations causing unne...
Measures of structural protein alignment within biological and engineered tissues are needed for improved understanding of their mechanical behavior a...
Lung cancer remains a leading cause of global cancer mortality, demanding precise diagnostic tools for accurate subtype classification. This paper int...
BACKGROUND: Gastric cancer (GC) is the fifth most common malignant tumor worldwide. The peritoneum is a common site of metastasis in advanced GC, and ...
The morphological characteristics of bull spermatozoa are usually evaluated visually using bright-field microscopy according to the guidelines propose...
Cervical cancer is one of the most common cancers in women. Despite progress in prevention and success in early detection through cytologic screening ...
Genetic testing for pathogenic germline variants is critical for the personalized management of high-risk breast cancers, guiding targeted therapies a...