Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Artificial Intelligence Assisted 18F-FDG PET Radiomics in Classifying Histological Subtypes of Lung Cancer: Systematic Review and Meta-analysis.

UNLABELLED: AI-assisted radiomics is an emerging tool for precision oncology, and many studies have recently shown promising results. However, there are still differences in whether it can be applied in clinical practice. This study aimed to evaluate the diagnostic accuracy of PET-based radiomics in ML models for histological subtype classification of lung cancer through a systematic review and me...

May 17 2025 41908706

Hybrid machine learning for real-time prediction of edema trajectory in large middle cerebral artery stroke.

In treating malignant cerebral edema after a large middle cerebral artery stroke, clinicians need quantitative tools for real-time risk assessment. Existing predictive models typically estimate risk at one, early time point, failing to account for dynamic variables. To address this, we developed Hybrid Ensemble Learning Models for Edema Trajectory (HELMET) to predict midline shift severity, an est...

May 17 2025 40379753
Extensible Immunofluorescence (ExIF) accessibly generates high-plexity datasets by integrating standard 4-plex imaging data.

Standard immunofluorescence imaging captures just ~4 molecular markers (4-plex) per cell, limiting dissection of complex biology. Inspired by multimod...

May 17 2025 40382312
Exploring potential methylation markers for ovarian cancer from cervical scraping samples.

BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate ...

May 17 2025 40382585
Artificial Intelligence as a Potential Tool for Predicting Surgical Margin Status in Early Breast Cancer Using Mammographic Specimen Images.

: Breast cancer is the most common malignancy among women globally, with an increasing incidence, particularly in younger populations. Achieving compl...

May 17 2025 40428269
Machine Learning Based Assessment of Inguinal Lymph Node Metastasis in Patients with Squamous Cell Carcinoma of the Vulva.

: Despite great efforts from both clinical and pathological sides to address the extent of metastatic inguinal lymph node involvement in patients with...

May 17 2025 40429505
Computer-aided diagnosis for colorectal polyp in comparison with endoscopists: Systematic review and meta-analysis.

OBJECTIVES: Computer-aided diagnosis (CADx) is anticipated to enhance the prediction of colorectal polyp histology. This study aims to compare the dia...

May 16 2025 40375757
A plasma 9-microRNA signature for lung cancer early detection: a multicenter analysis.

Lung cancer remains the leading cause of cancer-related deaths worldwide. Low-dose computed tomography (LD-CT) screening, combined with effective mini...

May 16 2025 40380218
Deep learning predicts HER2 status in invasive breast cancer from multimodal ultrasound and MRI.

The preoperative human epidermal growth factor receptor type 2 (HER2) status of breast cancer is typically determined by pathological examination of a...

May 16 2025 40392960
AI-assisted diffuse correlation tomography for identifying breast cancer.

SIGNIFICANCE: Diffuse correlation tomography (DCT) is an emerging technique for the noninvasive measurement of breast microvascular blood flow, wherea...

May 16 2025 40385570
Comparison of Manual Versus QuPath Software-based Immunohistochemical Scoring Using Oral Squamous Cell Carcinoma as a Model.

Gold standard for immunohistochemical analyses is the manual assessment by two specialist pathologists. This process is time-consuming, highly depende...

May 15 2025 40371713
Associations between calcium intake and T cell infiltration in colorectal tumours.

Higher T cell infiltration in colorectal tumours has been associated with better prognosis. Evidence indicates that calcium signalling is essential fo...

May 15 2025 40371912
Automated Microbubble Discrimination in Ultrasound Localization Microscopy by Vision Transformer.

Ultrasound localization microscopy (ULM) has revolutionized microvascular imaging by breaking the acoustic diffraction limit. However, different ULM w...

May 15 2025 40372868
Tumor budding and poorly differentiated clusters as a biological continuum in colorectal cancer invasion and prognosis.

Tumor budding (TB) and poorly differentiated clusters (PDCs) are features of infiltrative growth patterns and powerful independent prognostic factors ...

May 15 2025 40374662
ITGAV, a specific biomarker associated with the pathogenesis of idiopathic pulmonary fibrosis.

Objective Idiopathic pulmonary fibrosis (IPF), which radiologically/pathologically manifests mainly as usual interstitial pneumonia (UIP), is easily c...

May 15 2025 40374686
Modifying the U-Net's Encoder-Decoder Architecture for Segmentation of Tumors in Breast Ultrasound Images.

Segmentation is one of the most significant steps in image processing. Segmenting an image is a technique that makes it possible to separate a digital...

May 15 2025 40374986
Updated Techniques for Melanoma Diagnosis.

Melanoma, an aggressive skin cancer, requires timely diagnostics for improved patient outcomes. The ABCDE criteria-assessing asymmetry, borders, color...

May 12 2025 40581423
Dapagliflozin targets the crosstalk between apoptosis, autophagy, and Hedgehog signaling pathways through AMPK activation in the adjuvant-induced arthritic rat model.

Rheumatoid arthritis is a long-term autoimmune disorder, causes joint capsule, cartilage, and bone damage. Dapagliflozin, a novel antidiabetic drug, d...

May 12 2025 40350466
3D Electrospinning of Macroscopic PLLA Structures.

Electrospinning typically produces 2D fibrous nanofibers with poor heavy metal sorption capabilities and weak mechanical strength without post-process...

May 12 2025 40350976
Hormonal regulation and expression dynamics of Bmp4 in the reproductive cycle of Pampus argenteus.

As a member of the bone morphogenetic protein (BMP) family, Bmp4 plays a crucial role in bone formation, early developmental stage and the regulation ...

May 12 2025 40351264
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