Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Cryo-electron Microscopy Reveals the Structure of the Nuclear Pore Complex.

The nuclear pore complex (NPC) is a giant protein assembly that penetrates the double layers of the nuclear membrane. The overall structure of the NPC has approximately eightfold symmetry and is formed by approximately 30 nucleoporins. The great size and complexity of the NPC have hindered the study of its structure for many years until recent breakthroughs were achieved by integrating the latest ...

Mar 17 2023 36933820

Artificial intelligence in renal pathology: Current status and future.

Renal biopsy pathology is an essential gold standard for the diagnosis of most kidney diseases. With the increase in the incidence rate of kidney diseases, the lack of renal pathologists, and an imbalance in their distribution, there is an urgent need for a new renal pathological diagnosis model. Advances in artificial intelligence (AI) along with the growing digitization of pathology slides for d...

Mar 16 2023 36378066
Comparison of a machine and deep learning model for automated tumor annotation on digitized whole slide prostate cancer histology.

One in eight men will be affected by prostate cancer (PCa) in their lives. While the current clinical standard prognostic marker for PCa is the Gleaso...

Mar 16 2023 36928230
Artificial intelligence-based analysis of whole-body bone scintigraphy: The quest for the optimal deep learning algorithm and comparison with human observer performance.

PURPOSE: Whole-body bone scintigraphy (WBS) is one of the most widely used modalities in diagnosing malignant bone diseases during the early stages. H...

Mar 15 2023 36932023
Convolutional Neural Network Quantification of Gleason Pattern 4 and Association With Biochemical Recurrence in Intermediate-Grade Prostate Tumors.

Differential classification of prostate cancer grade group (GG) 2 and 3 tumors remains challenging, likely because of the subjective quantification of...

Mar 15 2023 36925071
Technical Advancements in Abdominal Diffusion-weighted Imaging.

Since its first observation in the 18th century, the diffusion phenomenon has been actively studied by many researchers. Diffusion-weighted imaging (D...

Mar 15 2023 36928124
Moving perfusion culture and live-cell imaging from lab to disc: proof of concept toxicity assay with AI-based image analysis.

, cell-based assays are essential in diagnostics and drug development. There are ongoing efforts to establish new technologies that enable real-time d...

Mar 14 2023 36790123
Differentiating malignant and benign eyelid lesions using deep learning.

Artificial intelligence as a screening tool for eyelid lesions will be helpful for early diagnosis of eyelid malignancies and proper decision-making. ...

Mar 13 2023 36914694
Weakly supervised histopathology image segmentation with self-attention.

Accurate segmentation in histopathology images at pixel-level plays a critical role in the digital pathology workflow. The development of weakly super...

Mar 11 2023 36933385
NuKit: A deep learning platform for fast nucleus segmentation of histopathological images.

Nucleus segmentation represents the initial step for histopathological image analysis pipelines, and it remains a challenge in many quantitative analy...

Mar 11 2023 36958934
Clinical application of AI-based PET images in oncological patients.

Based on the advantages of revealing the functional status and molecular expression of tumor cells, positron emission tomography (PET) imaging has bee...

Mar 10 2023 36906112
Deep Learning Prediction of Promoter Mutation Status in Thyroid Cancer Using Histologic Images.

objectives: Telomerase reverse transcriptase () promoter mutation, found in a subset of patients with thyroid cancer, is strongly associated with agg...

Mar 9 2023 36984536
Preparing pathological data to develop an artificial intelligence model in the nonclinical study.

Artificial intelligence (AI)-based analysis has recently been adopted in the examination of histological slides via the digitization of glass slides u...

Mar 8 2023 36890209
Detection of malignancy in whole slide images of endometrial cancer biopsies using artificial intelligence.

In this study we use artificial intelligence (AI) to categorise endometrial biopsy whole slide images (WSI) from digital pathology as either "malignan...

Mar 8 2023 36888621
Clinicians' perception of oral potentially malignant disorders: a pitfall for image annotation in supervised learning.

OBJECTIVE: The present study aims to quantify clinicians' perceptions of oral potentially malignant disorders (OPMDs) when evaluating, classifying, an...

Mar 7 2023 37037738
Successful all robotic-assisted excision of highly malignant mediastinal neuroblastoma in a toddler: A case report.

An otherwise well 28-month-old girl presented with fever/left thigh pain. Computed tomography identified a 7 cm right posterior mediastinal tumor exte...

Mar 7 2023 36882918
Diagnosis of Alzheimer Disease and Tauopathies on Whole-Slide Histopathology Images Using a Weakly Supervised Deep Learning Algorithm.

Neuropathologic assessment during autopsy is the gold standard for diagnosing neurodegenerative disorders. Neurodegenerative conditions, such as Alzhe...

Mar 6 2023 36889541
Automated Ki-67 labeling index assessment in prostate cancer using artificial intelligence and multiplex fluorescence immunohistochemistry.

The Ki-67 labeling index (Ki-67 LI) is a strong prognostic marker in prostate cancer, although its analysis requires cumbersome manual quantification ...

Mar 6 2023 36656126
Artificial intelligence in clinical multiparameter flow cytometry and mass cytometry-key tools and progress.

There are many research studies and emerging tools using artificial intelligence (AI) and machine learning to augment flow and mass cytometry workflow...

Mar 5 2023 36894355
A novel deep learning model for breast lesion classification using ultrasound Images: A multicenter data evaluation.

PURPOSE: Breast cancer is one of the major reasons of death due to cancer in women. Early diagnosis is the most critical key for disease screening, co...

Mar 4 2023 36878133
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