Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Atomic force microscopy in lung cancer: from mechanobiology to clinical translation.

Atomic force microscopy (AFM) enables the nanoscale investigation of cellular mechanics, morphology, and molecular interactions under conditions that closely mimic physiological environments. This review synthesizes AFM analytical methodologies relevant to lung cancer, evaluating their applications in cell mechanics, early diagnosis, drug screening, and personalized therapy. Notable analytical adv...

Jul 10 2026 42429654

Artificial Intelligence for Cervical HPV Infection and Lesion Screening: A Cross-Sectional Analysis of Its Application Potential and Patient Satisfaction.

OBJECTIVE: This cross-sectional study aimed to explore the application potential of artificial intelligence (AI) in screening and diagnosing cervical human papillomavirus (HPV) infection and lesions, and to assess patient satisfaction with the current diagnostic and therapeutic process as well as their unmet needs. METHODS: An online cross-sectional survey was conducted via the Questionnaire Star ...

Jul 10 2026 42430284
Antibody-drug conjugates in selected solid tumours: a position statement update based on findings from the third workshop held by the ETOP IBCSG Partners Foundation.

The European Thoracic Oncology Platform (ETOP) International Breast Cancer Study Group (IBCSG) Partners Foundation initiated a series of workshops for...

Jul 10 2026 42431135
Image-guided multiscale modeling of trabecular bone: lacuna-resolved stress amplification and interaction effects.

Osteocyte lacunae are ubiquitous microstructural cavities in bone that perturb local stress and strain fields, shaping the mechanical microenvironment...

Jul 10 2026 42431287
Comparative Diagnostic Performance of Large Language Models and Clinicians for Splenic Diseases in Dogs and Cats.

Splenic diseases in dogs and cats present significant diagnostic challenges, particularly in differentiating benign from malignant lesions using conve...

Jul 10 2026 42431356
Pulmonary nodule prediction in the multi-omics era: integrating radiomics, AI, liquid biopsy, and airway classifiers.

Low-dose CT (LDCT) lung cancer screening significantly reduces mortality but has dramatically increased the detection of pulmonary nodules. Most of th...

Jul 10 2026 42431477
Promise and pragmatism of AI in global-scale digital pathology: pan-cancer approaches for clinical practice.

Artificial intelligence (AI) tools for digital pathology have crossed the threshold from pilot project to clinical deployment, with regulatory approva...

Jul 10 2026 42431728
A Multimodal Multitask Deep Learning Model Based on Ultrasound RF Signals for Joint Assessment of Breast Masses and Axillary Lymph Nodes Status.

PURPOSE: Developing a deep learning model to simultaneously evaluate lymph node status and distinguish between benign and malignant breast masses has ...

Jul 10 2026 42431776
Development of an expert-annotated chest X-ray dataset to support AI validation in tuberculosis diagnosis.

OBJECTIVES: To assess inter-rater agreement and diagnostic performance of six United States National Institute for Occupational Safety and Health-cert...

Jul 10 2026 42432306
Factors contributing to the missed diagnosis of incidental gallbladder cancer (IGBC): an integrated analysis of clinical features and ultrasound radiomics.

BACKGROUND: Incidental gallbladder cancer (IGBC) is often diagnosed only during or after cholecystectomy, and preoperative identification remains chal...

Jul 10 2026 42432566
Uncovering the mechanism of DCLK3 in colorectal cancer progression through WGCNA and machine learning.

BACKGROUND: Colorectal cancer (CRC) is a prevalent malignant tumor of the digestive tract with high morbidity and mortality rates. Although doublecort...

Jul 10 2026 42432583
Identification of FOXK1 and SEMA7A as key genes associated with m6A-related programmed cell death in diabetic retinopathy.

BACKGROUND: Diabetic retinopathy (DR), a serious microvascular complication of diabetes, has a complex pathogenic mechanism that is intricately linked...

Jul 10 2026 42432759
AI-Based Analysis of Tumor-Infiltrating Lymphocytes and Homologous Recombination in Ovarian Cancer: JGOG3025-A1 Study.

Understanding the tumor immune microenvironment, especially tumor-infiltrating lymphocytes (TILs), remains crucial in ovarian cancer. However, the dis...

Jul 10 2026 42432821
SPADE: Spatial transcriptomics and pathology alignment using a mixture of data experts for an expressive latent space.

The rapid growth of digital pathology and advances in self-supervised deep learning have enabled the development of foundational models for various pa...

Jul 9 2026 42442210
Genomic profiling as an option for ovarian cancer diagnostics.

INTRODUCTION: Ovarian cancer (OC) is a highly heterogeneous and lethal gynecological malignancy. Precision oncology has shifted the management paradig...

Jul 9 2026 42422928
The role of artificial intelligence in precision medicine for breast cancer.

Breast cancer (BC) ranks among the most common malignant tumors affecting women globally. The essence of precision medicine (PM) lies in "delivering t...

Jul 9 2026 42423852
From Brain to Blood: Point-of-Care Detection of Biomarkers in Neurological Diseases.

Neurological diseases (NDs) continue to be a leading cause of disability and mortality worldwide, largely due to delayed diagnosis and limited access ...

Jul 9 2026 42424160
Development of a prediction model for recurrence in patients with malignant ovarian germ cell tumors undergoing fertility-sparing surgery: A multicenter retrospective study.

OBJECTIVE: To investigate the clinical characteristics associated with recurrence in malignant ovarian germ cell tumors (MOGCT) patients who received ...

Jul 9 2026 42424681
Evaluating human-AI interaction in optical diagnosis of early colorectal carcinoma through endoscopist responses to simulated artificial intelligence: a multinational online study.

Background Suboptimal human - artificial intelligence (AI) interaction is a potential roadblock for implementation of AI in clinical practice. We aime...

Jul 9 2026 42425135
Anatomically adaptive feature-wise linear modulation for deep learning-based low-dose CT denoising.

Low-dose computed tomography (LDCT) reduces radiation dose but, introduces heterogeneous noise due to different photon attenuation based on anato...

Jul 9 2026 42425148
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