Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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PUNCH: Physics-informed Uncertainty-aware Network for Coronary Hemodynamics

Coronary microvascular dysfunction (CMD) affects millions worldwide yet remains underdiagnosed becau...

Semi-Supervised Domain Adaptation with Latent Diffusion for Pathology Image Classification

Deep learning models in computational pathology often fail to generalize across cohorts and institut...

Integrating Quantitative Histology with Clinical Data Improves Prediction of Cervical Intraepithelial Neoplasia Regression

Cervical intraepithelial neoplasia grade 2 (CIN2) lesions show variable outcomes, and accurate predi...

Reconstructing Patched or Partial Holograms to allow for Whole Slide Imaging with a Self-Referencing Holographic Microscope

The last decade has seen significant advances in computer-aided diagnostics for cytological screenin...

PAINT: Pathology-Aware Integrated Next-Scale Transformation for Virtual Immunohistochemistry

Virtual immunohistochemistry (IHC) aims to computationally synthesize molecular staining patterns fr...

Peripheral blood profiles reflecting progenitor lineage balance predict treatment response in chronic myeloid leukemia

Early achievement of deep remission improves patients' outcome in chronic myeloid leukemia (CML) tre...

SigFormer: an Attention-Based Framework for Robust Single-Sample Mutational Signature Decomposition

Somatic mutational signatures imprint the history of exogenous exposures and endogenous processes on...

Biophysically inspired mean-field model of neuronal populations driven by ion exchange mechanisms

Whole-brain simulations are a valuable tool for gaining insight into the multiscale processes that r...

Transfer Learning from One Cancer to Another via Deep Learning Domain Adaptation

Supervised deep learning models often achieve excellent performance within their training distributi...

ReinPath: A Multimodal Reinforcement Learning Approach for Pathology

Interpretability is significant in computational pathology, leading to the development of multimodal...

MTFlow: Time-Conditioned Flow Matching for Microtubule Segmentation in Noisy Microscopy Images

Microtubules are cytoskeletal filaments that play essential roles in many cellular processes and are...

Comparison of Deep Learning Approaches for Extreme Low-SNR Image Restoration

Background: Live-cell fluorescence microscopy enables the study of dynamic cellular processes. Howev...

Spatial Decoding of Tertiary Lymphoid Structure Maturation in Non-Small Cell Lung Cancer Using Deep Neural Networks

Understanding the role of tertiary lymphoid structures (TLS) is crucial in non-small cell lung cance...

Generalizable Hyperparameter Optimization for Federated Learning on Non-IID Cancer Images

Deep learning for cancer histopathology training conflicts with privacy constraints in clinical sett...

MultiST: A Cross-Attention-Based Multimodal Model for Spatial Transcriptomic

Spatial transcriptomics (ST) enables transcriptome-wide profiling while preserving the spatial conte...

DiffusionQC: Artifact Detection in Histopathology via Diffusion Model

Digital pathology plays a vital role across modern medicine, offering critical insights for disease ...

An Innovative Framework for Breast Cancer Detection Using Pyramid Adaptive Atrous Convolution, Transformer Integration, and Multi-Scale Feature Fusion

Breast cancer is one of the most common cancers among women worldwide, and its accurate and timely d...

CytoCLIP: Learning Cytoarchitectural Characteristics in Developing Human Brain Using Contrastive Language Image Pre-Training

The functions of different regions of the human brain are closely linked to their distinct cytoarchi...

Multimodal Spatial Omics: From Data Acquisition to Computational Integration

Recent developments in spatial omics technologies have enabled the generation of high dimensional mo...

A Hierarchical Benchmark of Foundation Models for Dermatology

Foundation models have transformed medical image analysis by providing robust feature representation...

Histopath-C: Towards Realistic Domain Shifts for Histopathology Vision-Language Adaptation

Medical Vision-language models (VLMs) have shown remarkable performances in various medical imaging ...

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