Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Computational analysis of non-invasive deep brain stimulation based on interfering electric fields.

Neuromodulation modalities are used as effective treatments for some brain disorders. Non-invasive deep brain stimulation (NDBS) via temporally interfering electric fields has emerged recently as a non-invasive strategy for electrically stimulating deep regions in the brain. The objective of this study is to provide insight into the fundamental mechanisms of this strategy and assess the potential ...

Dec 5 2019 31661678

Deep learning enables pathologist-like scoring of NASH models.

Non-alcoholic fatty liver disease (NAFLD) and the progressive form of non-alcoholic steatohepatitis (NASH) are diseases of major importance with a high unmet medical need. Efficacy studies on novel compounds to treat NAFLD/NASH using disease models are frequently evaluated using established histological feature scores on ballooning, inflammation, steatosis and fibrosis. These features are assessed...

Dec 5 2019 31804575
AI-powered transmitted light microscopy for functional analysis of live cells.

Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted ligh...

Dec 5 2019 31804589
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots.

Our aim was to assess the utility of a novel machine learning software (Orbit Image Analysis) in the histological quantification of acute ischemic str...

Dec 5 2019 31805096
Computer-Aided Diagnosis Systems in Diagnosing Malignant Thyroid Nodules on Ultrasonography: A Systematic Review and Meta-Analysis.

BACKGROUND: Computer-aided diagnosis (CAD) systems are being applied to the ultrasonographic diagnosis of malignant thyroid nodules, but it remains co...

Dec 4 2019 32903956
Automated oral squamous cell carcinoma identification using shape, texture and color features of whole image strips.

Despite profound knowledge of the incidence of oral cancers and a large body of research beyond it, it continues to beat diagnosis and treatment manag...

Dec 4 2019 32223950
Epithelium segmentation and automated Gleason grading of prostate cancer via deep learning in label-free multiphoton microscopic images.

In the current clinical care practice, Gleason grading system is one of the most powerful prognostic predictors for prostate cancer (PCa). The grading...

Dec 4 2019 31710780
Twin Robotic X-Ray System for 3D Cone-Beam CT of the Wrist: An Evaluation of Image Quality and Radiation Dose.

The purpose of this study was to assess image quality and radiation dose of a novel twin robotic x-ray system's 3D cone-beam CT (CBCT) function for t...

Dec 4 2019 31799871
ImageDataExtractor: A Tool To Extract and Quantify Data from Microscopy Images.

The rise of data science is leading to new paradigms in data-driven materials discovery. This carries an essential notion that large data sources cont...

Dec 3 2019 31714792
Machine Learning Enables High-Throughput Phenotyping for Analyses of the Genetic Architecture of Bulliform Cell Patterning in Maize.

Bulliform cells comprise specialized cell types that develop on the adaxial (upper) surface of grass leaves, and are patterned to form linear rows alo...

Dec 3 2019 31645422
Graph temporal ensembling based semi-supervised convolutional neural network with noisy labels for histopathology image analysis.

Although convolutional neural networks have achieved tremendous success on histopathology image classification, they usually require large-scale clean...

Dec 2 2019 31841948
CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data.

Quantifying cell-type proportions and their corresponding gene expression profiles in tissue samples would enhance understanding of the contributions ...

Dec 2 2019 31790389
A novel hybrid atlas-free hierarchical graph-based segmentation of newborn brain MRI using wavelet filter banks.

: The newborn brain MRI (magnetic resonance imaging) tissue segmentation plays a vital part in assessment of primary brain growth. In the newborn stag...

Dec 1 2019 31790318
Evolving the pulmonary nodules diagnosis from classical approaches to deep learning-aided decision support: three decades' development course and future prospect.

PURPOSE: Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis a...

Nov 30 2019 31786740
Histopathology-guided mass spectrometry differentiates benign nevi from malignant melanoma.

PURPOSE: Distinguishing benign nevi from malignant melanoma using current histopathological criteria may be very challenging and is one the most diffi...

Nov 27 2019 31697431
An interpretation algorithm for molecular diagnosis of bacterial vaginosis in a maternity hospital using machine learning: proof-of-concept study.

Allplex Bacterial vaginosis assay (Seegene, South Korea) is a molecular test for bacterial vaginosis (BV). A machine learning algorithm was devised on...

Nov 27 2019 31836253
Artificial Intelligence (AI) in Rare Diseases: Is the Future Brighter?

The amount of data collected and managed in (bio)medicine is ever-increasing. Thus, there is a need to rapidly and efficiently collect, analyze, and c...

Nov 27 2019 31783696
Isolation, Identification and Characteristics of From Diseased Crucian Carp ().

species often cause disease in farmed fish. In the present study, dominant bacteria were isolated from diseased crucian carp (). Based on this, a bac...

Nov 26 2019 32038507
A manifold learning regularization approach to enhance 3D CT image-based lung nodule classification.

PURPOSE: Diagnosis of lung cancer requires radiologists to review every lung nodule in CT images. Such a process can be very time-consuming, and the a...

Nov 25 2019 31768885
Robot-assisted flexible needle insertion using universal distributional deep reinforcement learning.

PURPOSE: Flexible needle insertion is an important minimally invasive surgery approach for biopsy and radio-frequency ablation. This approach can mini...

Nov 25 2019 31768886
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