Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Statistical evaluation of fresh properties of self-compacting concrete incorporating construction and industrial waste: a sustainable approach.

This study investigates the fresh properties of self-compacting concrete (SCC) developed using recycled concrete aggregates (RCA) as coarse aggregate replacement and ground granulated blast-furnace slag (GGBS) as cement replacement. This study employs an integrated statistical framework to simultaneously analyze, interpret, and optimize multiple SCC fresh performance parameters. SCC mixes were pre...

Mar 23 2026 41866650

Digital pathology platforms with integrated AI algorithms: a structured landscape analysis and recommendations for clinical implementation.

Pathology is undergoing a fundamental change as slide-based diagnostics transition toward digital workflows. Advances in whole slide imaging, data management, and computational analysis have created the basis for integrating artificial intelligence (AI) into diagnostic routines. However, the growing number of commercial digital pathology platforms poses challenges for selecting clinically suitable...

Mar 23 2026 41870613
FTO-CHRM3 axis regulates multiple myeloma progression: a machine learning-based identification.

BACKGROUND: Fat Mass and Obesity-Associated (FTO) is linked to multiple myeloma (MM) progression, but its action mechanisms are poorly understood. MET...

Mar 23 2026 41870649
Exploring Deep Learning Models for Small Histopathology Datasets: Segmentation and Classification of Glomerular Crescent Lesions with Ablation, Interpretability, and Calibration Analyses.

Glomerular crescent lesions are critical indicators of severe kidney injury and are closely associated with disease progression. However, their automa...

Mar 23 2026 41870786
Integrated single-cell and spatial mapping coupled with machine learning unveils core stemness landscapes and regulatory drivers in triple-negative breast cancer.

OBJECTIVE: Triple-negative breast cancer (TNBC) exhibits pronounced intratumoral heterogeneity, and cancer stem cells (CSCs) are thought to play a piv...

Mar 23 2026 41870799
The Synovial Fingerprint of Ankle Fractures: A Central Role for WNT Pathway Activation in Posttraumatic Ankle Osteoarthritis.

BACKGROUND: Osteoarthritis (OA) of the ankle is a disabling and understudied disease, most commonly emerging posttraumatically after ankle fractures (...

Mar 23 2026 41871107
High-fidelity "top-down" DLP bioprinting of multi-material soft tissue constructs enabled by computer vision-based layer control.

Bioprinting continues to redefine the frontiers of regenerative medicine by enabling the fabrication of complex, three-dimensional tissue constructs t...

Mar 23 2026 41871470
Concussion pathophysiology: From biomechanical insult to clinical phenotype - or is injury truly the beginning?

Mild traumatic brain injury (mTBI) is associated with substantial morbidity worldwide. Emerging evidence demonstrates that both impact- and blast-rela...

Mar 22 2026 42264871
Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy.

BACKGROUND: Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic ...

Mar 22 2026 41866435
Fluorescence Spectroscopy for Real-Time Intraoperative Detection of Middle-Ear Cholesteatoma.

OBJECTIVE: To evaluate whether autofluorescence spectroscopy (AFS) can reliably distinguish cholesteatoma from surrounding middle-ear tissues, and to ...

Mar 22 2026 41865269
Computational delineation and cellular profiling of murine cortical cell layers using multiplex immunofluorescence imaging.

BACKGROUND: The adult mammalian cerebral cortex has a vertical laminar organization consisting of six neuronal layers, with each layer subserving a sp...

Mar 21 2026 41871770
ViFIT-assisted histopathology: From H&E style standardization to virtual fiber image transformation.

Deep learning-based virtual fiber staining provides a promising complement to routine H&E pathology. However, the reliance on predefined staining styl...

Mar 21 2026 41903259
Unveiling the prognostic and therapeutic landscape of the zinc transporter protein SLC39A family in colorectal cancer through multi-omics and machine learning approaches.

Colorectal cancer (CRC) remains a significant global health challenge due to its high prevalence and mortality rates. Zinc transporter proteins of the...

Mar 21 2026 41863577
Toxicologic Pathology Forum*: Virtual Staining of Nonclinical Study Slides-A Brief Review of the Current Status and Future Opportunities.

Virtual staining of unstained tissue for histologic assessment is the subject of burgeoning research and has been approached using various methodologi...

Mar 21 2026 41863851
From Passive Sampling to Precision Intervention: A Standardized Radiomics-Driven Workflow for Molecularly Adequate Lung Biopsy.

PURPOSE: To develop and temporally validate a predictive framework for molecular adequacy in computed tomography (CT)-guided transthoracic needle biop...

Mar 21 2026 41865181
Deep learning-based computer-aided diagnosis for parotid gland tumors on MRI.

OBJECTIVE: Accurate imaging-based differentiation of benign and malignant parotid tumors is essential for determining appropriate therapy. We investig...

Mar 21 2026 41865703
Prostatic artery embolization for benign prostatic hyperplasia: State of the art.

Over the past 25 years, prostatic artery embolization has emerged as a minimally invasive, organ-sparing alternative for managing benign prostatic hyp...

Mar 21 2026 41866253
DRDarkNet: a hybrid deep feature engineering model for accurate autopsy image classification.

In deaths due to injury, photographs of changes on deceased bodies are routinely taken during the forensic examination; the task of differentiating th...

Mar 20 2026 41857401
HOW GENETICS CHANGED OR WILL CHANGE THE THERAPY IN THYROID NODULES WITH INDETERMINATE CYTOLOGY.

The incidence of thyroid cancer has risen in recent decades, largely due to the widespread use of increasingly sensitive imaging techniques that have ...

Mar 20 2026 41866067
Statistical models to characterize colon tumor stiffness heterogeneity through representative atomic force microscopy maps.

The study of the impact of physical forces and on cells has emerged as a fertile field of investigation. Applications in oncology are especially trans...

Mar 20 2026 41862631
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