Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Integrative Approaches in Lung Cancer Diagnosis: Bridging Molecular Biomarkers and AI Driven Imaging.

Though critical, traditional diagnostic approaches such as X-ray, CT scans, bronchoscopy and tissue biopsy don't reliably detect lung cancer at early stages, paradigm shift has occurred recently with lung cancer diagnostics based on recent advances of molecular biology and computational technologies. Present review analyses incorporation of molecular biomarkers- EGFR, ALK, KRAS, BRAF, MET and PD-L...

Mar 14 2026 41830914

A multimodal feature disentanglement model for lymphadenopathy diagnosis based on BUS and CDFI ultrasound videos: a retrospective, prospective, multicenter study.

OBJECTIVES: This study developed and validated a deep learning model for diagnosing lymphadenopathy (LA) using B-mode ultrasound (BUS) and color Doppler flow imaging (CDFI) videos. MATERIALS AND METHODS: A retrospective and prospective study was conducted from January 2016 to August 2025, including 7371 patients (3824 male [51.9%], 3547 females [48.1%], median age, 52 years [9-94 years]) who under...

Mar 14 2026 41831029
MyoClass: A modular multimodal auto-classification system for myocardial tissue characterization.

Differentiating myocarditis from myocardial infarction (MI) using Cardiac Magnetic Resonance (CMR) imaging remains a significant clinical challenge du...

Mar 14 2026 41831142
A Smartphone-based Comprehensive Dataset of Annotated Oral Cavity Images for Enhanced Oral Disease Diagnosis.

This study introduces a SMARTphone-based, expert annotated dataset of Oral Mucosa images (SMART-OM), collected to facilitate the development of Artifi...

Mar 13 2026 41826371
A Machine learning pipeline to investigate tissue ingrowth in cerebral aneurysms using preclinical animal models.

Cerebral aneurysm is a life-threatening condition characterized by the formation of a saccular bulge in brain blood vessels, which can rupture and lea...

Mar 13 2026 41826635
An explainable radiomics model based on multiparametric magnetic resonance for differentiating benign and malignant orbital tumors.

OBJECTIVE: To develop and internally test a multiparametric radiomics combined model for differentiating benign and malignant orbital tumors. PATIENTS...

Mar 13 2026 41826882
Practical AI-based cell extraction and spatial statistics for large 3D bone marrow tissue images.

Although the molecular regulation of hematopoiesis is well characterized, the spatial organization of hematopoietic cells within bone marrow (BM) rema...

Mar 13 2026 41831446
Refining prognostication in non-muscle-invasive bladder cancer: From clinical models to artificial intelligence.

Over the past 2 decades, risk stratification in non-muscle-invasive bladder cancer (NMIBC) has evolved considerably, progressing from simple clinico-p...

Mar 13 2026 41832109
Improving visibility of small anatomical details on low and ultra-low dose computed tomography with artificial intelligence-based image reconstructions.

To assess how computed tomography (CT) image reconstruction techniques affect perceived diagnostic image quality at varying radiation dose levels in c...

Mar 13 2026 41821465
Overview of combined adjuvant strategies for tumor biomarker detection.

Cancer is one of the leading causes of death worldwide, and early tumor detection can significantly reduce mortality rates. Liquid biopsy is a minimal...

Mar 13 2026 41823325
Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks.

OBJECTIVE: Drug-resistant epilepsy (DRE) affects approximately one-third of patients with epilepsy. The molecular heterogeneity underlying DRE remains...

Mar 13 2026 41823335
The Performance of Artificial Intelligence in Classifying Molecular Markers in Adult-Type Gliomas Using Histopathological Images: Systematic Review.

BACKGROUND: Adult-type gliomas are among the most prevalent and lethal primary central nervous system tumors, where prompt and accurate diagnosis is e...

Mar 13 2026 41824546
Whole-Body Transformation in Obese Patients Undergoing Metabolic Surgery: Insights From Automated Multiorgan Segmentation.

PURPOSE: This study assesses whether automated segmentation allows evaluation of subtle changes in volume and intrinsic tissue characteristics in an o...

Mar 12 2026 41856817
Idiopathic pulmonary fibrosis from a multiscale mechanobiology perspective: Mechanisms and future therapeutic prospects.

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease that induces irreversible fibrosis and architectural remodeling. Traditional ...

Mar 12 2026 41940333
Illuminating the Invisible: Translational Molecular Imaging in Cardiovascular Medicine.

Cardiovascular disease remains the predominant cause of global morbidity and mortality, with recent epidemiological trends indicating a resurgence in ...

Mar 12 2026 41818327
J³SPM AI: An integrated open-source platform for AI-assisted image analysis and image-guided workflows in scanning probe microscopy.

Scanning probe microscopy (SPM), particularly atomic force microscopy (AFM), is essential for characterizing materials at the nanometer scale. However...

Mar 12 2026 41831346
Based on WGCNA and machine learning studies, SMURF2 drives NSCLC malignant transformation, ferroptosis, and macrophage polarization by ubiquitinating SPP1.

BACKGROUND: Non-small cell lung cancer (NSCLC) is a common type of lung cancer with poor prognosis and high mortality in advanced stages. Although sec...

Mar 12 2026 41831581
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens.

INTRODUCTION: Residual feed intake (RFI) is a key indicator of feed efficiency in poultry and is regulated by coordinated physiological processes acro...

Mar 12 2026 41831681
Artificial intelligence assisted multi-model pathological diagnosis of breast cancer based on multispectral autofluorescence images.

Virtual staining technology offers a promising solution to overcome the time-consuming and sample-consumption nature of conventional histochemical sta...

Mar 12 2026 41820369
Machine Learning Prediction of Vaginal Tissue Tears Using Finite Element Simulations Informed by Planar Biaxial Testing.

PURPOSE: Vaginal tissue tearing during childbirth is a prevalent injury with potential long-term consequences, yet the mechanical factors influencing ...

Mar 12 2026 41820774
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