Peptic Ulcer Disease

Investigating the Genetic Links Between Immune Cell Profiles and Bladder Cancer: A Multidisciplinary Bioinformatics Approach.

: Bladder cancer (BC) is a common malignancy in the urinary system, with an increasing incidence rate. Immune cell infiltration within the tumor microenvironment (TME) plays a crucial role in BC progression and treatment response. However, the immune cell composition of the TME presents a significant challenge to the effectiveness of current therapeutic strategies. : We performed bidirectional Men...

Research status and progress of deep learning in automatic esophageal cancer detection.

Esophageal cancer (EC), a common malignant tumor of the digestive tract, requires early diagnosis and timely treatment to improve patient prognosis. Automated detection of EC using medical imaging has the potential to increase screening efficiency and diagnostic accuracy, thereby significantly improving long-term survival rates and the quality of life of patients. Recent advances in deep learning ...

A multi-objective evolutionary algorithm for detecting protein complexes in PPI networks using gene ontology.

Detecting protein complexes is crucial in computational biology for understanding cellular mechanisms and facilitating drug discovery. Evolutionary al...

VIGIL: Vision-Language Guided Multiple Instance Learning Framework for Ulcerative Colitis Histological Healing Prediction

Objective: Ulcerative colitis (UC), characterized by chronic inflammation with alternating remission-relapse cycles, requires precise histological h...

Predictors and associations of complications in ureteroscopy for stone disease using AI: outcomes from the FLEXOR registry.

We aimed to develop machine learning(ML) algorithms to evaluate complications of flexible ureteroscopy and laser lithotripsy(fURSL), providing a valid...

Controllable Image Colorization with Instance-aware Texts and Masks

Recently, the application of deep learning in image colorization has received widespread attention. The maturation of diffusion models has further a...

Transcriptomic Profiling of Hypoxia-Adaptive Responses in Tibetan Goat Fibroblasts.

The Tibetan goat () exhibits remarkable adaptations to high-altitude hypoxia, yet the molecular mechanisms remain unclear. This study integrates RNA-s...

Investigation of Bleeding Disorders: When and How Should We Test Platelet Functions?

Inherited platelet disorders (IPDs) are rare conditions with diverse underlying pathophysiology which should be suspected in patients presenting with ...

Unraveling the molecular mechanisms of paclitaxel in high-grade serous ovarian cancer through network pharmacology.

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of epithelial ovarian cancer, often diagnosed at advanced stages wi...

[Pulmonary vascular interventions: innovating through adaptation and advancing through differentiation].

Pulmonary vascular intervention technology, with its minimally invasive and precise advantages, has been a groundbreaking advancement in the treatment...

A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.

There is a lack of effective means for precise drug delivery of gastrointestinal diseases. Herein we report a novel magnetically controlled drug deliv...

Antimicrobial Susceptibility Profiles of Isolates from Clinical Cases of Ducks in Hungary Between 2022 and 2023.

: Antimicrobial resistance (AMR) poses a growing threat to veterinary medicine and food safety. This study examines antibiotic resistance patterns in...

Exploring the potential biomarkers and potential causality of Ménière disease based on bioinformatics and machine learning.

Meniere disease (MD) is a common inner ear disorder closely related to immune abnormalities, but research on the characteristic genes between MD and i...

Automated vision-based assistance tools in bronchoscopy: stenosis severity estimation

Purpose: Subglottic stenosis refers to the narrowing of the subglottis, the airway between the vocal cords and the trachea. Its severity is typicall...

MDE-Edit: Masked Dual-Editing for Multi-Object Image Editing via Diffusion Models

Multi-object editing aims to modify multiple objects or regions in complex scenes while preserving structural coherence. This task faces significant...

Molecular Association Assay Systems for Imaging Protein-Protein Interactions in Mammalian Cells.

Molecular imaging probes play a pivotal role in assaying molecular events in various physiological systems. In this study, we demonstrate a new genre ...

Be precise, be reproducible! The emerging role of artificial intelligence in inflammatory bowel disease endoscopy.

Artificial intelligence system improves the quality of digestive endoscopy: A prospective pretest and post-test single-center clinical trial.

BACKGROUND: With the assistance of ENDOANGEL, a study was conducted at Hainan General Hospital to evaluate the effect of artificial intelligence (AI) ...

Topology-driven negative sampling enhances generalizability in protein-protein interaction prediction.

MOTIVATION: Unraveling the human interactome to uncover disease-specific patterns and discover drug targets hinges on accurate protein-protein interac...

Adversarial Robustness Analysis of Vision-Language Models in Medical Image Segmentation

Adversarial attacks have been fairly explored for computer vision and vision-language models. However, the avenue of adversarial attack for the visi...