Pneumonia

Designing robot-assisted neurorehabilitation strategies for people with both HIV and stroke.

There is increasing evidence that HIV is an independent risk factor for stroke, resulting in an emerging population of people living with both HIV and stroke all over the world. However, neurorehabilitation strategies for the HIV-stroke population are distinctly lacking, which poses an enormous global health challenge. In order to address this gap, a better understanding of the HIV-stroke populati...

Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production.

The production of envelope glycoproteins (Envs) for use as HIV vaccines is challenging. The yield of Envs expressed in stable Chinese Hamster Ovary (CHO) cell lines is typically 10-100 fold lower than other glycoproteins of pharmaceutical interest. Moreover, Envs produced in CHO cells are typically enriched for sialic acid containing glycans compared to virus associated Envs that possess mainly hi...

Deep Convolutional Neural Networks for Chest Diseases Detection.

Chest diseases are very serious health problems in the life of people. These diseases include chronic obstructive pulmonary disease, pneumonia, asthma...

Convolutional neural network scoring and minimization in the D3R 2017 community challenge.

We assess the ability of our convolutional neural network (CNN)-based scoring functions to perform several common tasks in the domain of drug discover...

Automated sub-cortical brain structure segmentation combining spatial and deep convolutional features.

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time as m...

Quantifying cell densities and biovolumes of phytoplankton communities and functional groups using scanning flow cytometry, machine learning and unsupervised clustering.

Scanning flow cytometry (SFCM) is characterized by the measurement of time-resolved pulses of fluorescence and scattering, enabling the high-throughpu...

Using machine learning to identify patterns of lifetime health problems in decedents with autism spectrum disorder.

Very little is known about the health problems experienced by individuals with autism spectrum disorder (ASD) throughout their life course. We retrosp...

Evolution of upper limb kinematics four years after subacute robot-assisted rehabilitation in stroke patients.

To assess functional status and robot-based kinematic measures four years after subacute robot-assisted rehabilitation in hemiparesis. Twenty-two pa...

Constructing Temporally Extended Actions through Incremental Community Detection.

Hierarchical reinforcement learning works on temporally extended actions or skills to facilitate learning. How to automatically form such abstraction ...

Large-scale assessment of benthic communities across multiple marine protected areas using an autonomous underwater vehicle.

Marine protected areas (MPAs) are designed to reduce threats to biodiversity and ecosystem functioning from anthropogenic activities. Assessment of MP...

Predictors of firearm violence in urban communities: A machine-learning approach.

Interpersonal firearm violence is a leading cause of death and injuries in the United States. Identifying community characteristics associated with fi...

Development and Validation of a Natural Language Processing Tool to Identify Patients Treated for Pneumonia across VA Emergency Departments.

BACKGROUND: Identifying pneumonia using diagnosis codes alone may be insufficient for research on clinical decision making. Natural language processin...

IMU-to-Segment Assignment and Orientation Alignment for the Lower Body Using Deep Learning.

Human body motion analysis based on wearable inertial measurement units (IMUs) receives a lot of attention from both the research community and the an...

Estimating the Causal Impact of Proximity to Gold and Copper Mines on Respiratory Diseases in Chilean Children: An Application of Targeted Maximum Likelihood Estimation.

In a town located in a desert area of Northern Chile, gold and copper open-pit mining is carried out involving explosive processes. These processes ar...

Randomized clinical trial of a single versus a double dose of 13-valent pneumococcal conjugate vaccine in adults 55 through 74 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine.

INTRODUCTION: In older adults, prior administration of 23-valent pneumococcal polysaccharide vaccine (PPSV23) blunts the opsonophagocytic antibody (OP...

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.

Knowledge of the full target space of bioactive substances, approved and investigational drugs as well as chemical probes, provides important insights...

Comparison, alignment, and synchronization of cell line information between CLO and EFO.

BACKGROUND: The Experimental Factor Ontology (EFO) is an application ontology driven by experimental variables including cell lines to organize and de...

[Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation].

Streptococcus agalactiae (GBS) cause severe infections in newborns under three months. Meningitis, pneumonia and sepsis are the main infectious diseas...

Clustering Categorical Data Using Community Detection Techniques.

With the advent of the -modes algorithm, the toolbox for clustering categorical data has an efficient tool that scales linearly in the number of data ...

Changes in bacterial and archaeal communities during the concentration of brine at the graduation towers in Ciechocinek spa (Poland).

This study evaluates the changes in bacterial and archaeal community structure during the gradual evaporation of water from the brine (extracted from ...