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Assessing medication-related burden and medication adherence among older patients from Central Nepal: A machine learning approach

We are pleased to submit our Original article entitled "Assessing medication-related burden and medication adherence among older patients from Central Nepal: A machine learning approach" for consideration in your esteemed journal. In this paper, we assessed medication burden using validated Living with medicines Questionnaire (LMQ-3) and medication adherence using Adherence to Medication refills (...

Drug Synergy Prediction via Residual Graph Isomorphism Networks and Attention Mechanisms

In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through synergistic effects. However, experimentally validating all possible drug combinations is prohibitively expensive, underscoring the critical need for efficient comput...

Apr 23 2026 2604.21473v1
Pairing Regularization for Mitigating Many-to-One Collapse in GANs

Mode collapse remains a fundamental challenge in training generative adversarial networks (GANs). While existing works have primarily focused on inter...

Apr 22 2026 2604.20130v1
Fast-then-Fine: A Two-Stage Framework with Multi-Granular Representation for Cross-Modal Retrieval in Remote Sensing

Remote sensing (RS) image-text retrieval plays a critical role in understanding massive RS imagery. However, the dense multi-object distribution and c...

Apr 22 2026 2604.20429v1
LEXIS: LatEnt ProXimal Interaction Signatures for 3D HOI from an Image

Reconstructing 3D Human-Object Interaction from an RGB image is essential for perceptive systems. Yet, this remains challenging as it requires capturi...

Apr 22 2026 2604.20800v1
GRAFT: Geometric Refinement and Fitting Transformer for Human Scene Reconstruction

Reconstructing physically plausible 3D human-scene interactions (HSI) from a single image currently presents a trade-off: optimization based methods o...

Apr 21 2026 2604.19624v1
CoInteract: Physically-Consistent Human-Object Interaction Video Synthesis via Spatially-Structured Co-Generation

Synthesizing human--object interaction (HOI) videos has broad practical value in e-commerce, digital advertising, and virtual marketing. However, curr...

Apr 21 2026 2604.19636v1
An Integrated Deep-Learning Framework for Peptide-Protein Interaction Prediction and Target-Conditioned Peptide Generation with ConGA-PePPI and TC-PepGen

Motivation: Peptide-protein interactions (PepPIs) are central to cellular regulation and peptide therapeutics, but experimental characterization remai...

Apr 20 2026 2604.18467v1
XEmbodied: A Foundation Model with Enhanced Geometric and Physical Cues for Large-Scale Embodied Environments

Vision-Language-Action (VLA) models drive next-generation autonomous systems, but training them requires scalable, high-quality annotations from compl...

Apr 20 2026 2604.18484v1
Enabling the prediction of phage receptor specificity from genome data

Predicting which receptor a phage binds to from genome sequence alone has remained an intractable challenge, principally because the experimental phen...

SCOPE: Integrating Organoid Screening and Clinical Variables Through Machine Learning for Cancer Trial Outcome Prediction

BackgroundPredicting whether a treatment will demonstrate meaningful clinical benefit before committing to a large-scale trial remains a major unmet n...

SSFT: A Lightweight Spectral-Spatial Fusion Transformer for Generic Hyperspectral Classification

Hyperspectral imaging enables fine-grained recognition of materials by capturing rich spectral signatures, but learning robust classifiers is challeng...

Apr 17 2026 2604.15828v1
Dental Panoramic Radiograph Analysis Using YOLO26 From Tooth Detection to Disease Diagnosis

Panoramic radiography is a fundamental diagnostic tool in dentistry, offering a comprehensive view of the entire dentition with minimal radiation expo...

Apr 17 2026 2604.16231v1
Aakhyan: An AI-Powered Vernacular Patient Communication Platform for Oncology in Resource-Limited Settings - System Architecture and Pilot Randomised Trial Protocol

Inadequate discharge communication is a well-documented contributor to medication non-adherence, missed follow-ups, and preventable readmissions acros...

Automated Detection of Dental Caries and Bone Loss on Periapical and Bitewing Radiographs using a YOLO Based Deep Learning Model

BackgroundDental caries and periodontal disease represent the most prevalent global oral health conditions, collectively affecting several billion peo...

A Study of Failure Modes in Two-Stage Human-Object Interaction Detection

Human-object interaction (HOI) detection aims to detect interactions between humans and objects in images. While recent advances have improved perform...

Apr 15 2026 2604.13448v1
AI Powered Image Analysis for Phishing Detection

Phishing websites now rely heavily on visual imitation-copied logos, similar layouts, and matching colours-to avoid detection by text- and URL-based s...

Apr 15 2026 2604.13555v1
Text-Attributed Knowledge Graph Enrichment with Large Language Models for Medical Concept Representation

In electronic health record (EHR) mining, learning high-quality representations of medical concepts (e.g., standardized diagnosis, medication, and pro...

Apr 14 2026 2604.13331v1
Bridging the Micro--Macro Gap: Frequency-Aware Semantic Alignment for Image Manipulation Localization

As generative image editing advances, image manipulation localization (IML) must handle both traditional manipulations with conspicuous forensic artif...

Apr 14 2026 2604.12341v1
Euler-inspired Decoupling Neural Operator for Efficient Pansharpening

Pansharpening aims to synthesize high-resolution multispectral (HR-MS) images by fusing the spatial textures of panchromatic (PAN) images with the spe...

Apr 14 2026 2604.12463v1
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